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Author: R. Pochet
Publisher: Springer Science & Business Media
ISBN: 1468457543
Category : Science
Languages : en
Pages : 212
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Book Description
Proceedings of the First European Symposium held in Brussels, Belgium, April 20--22, 1989
Author: R. Pochet
Publisher: Springer Science & Business Media
ISBN: 1468457543
Category : Science
Languages : en
Pages : 212
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Book Description
Proceedings of the First European Symposium held in Brussels, Belgium, April 20--22, 1989
Author: Claus W. Heizmann
Publisher: Springer Science & Business Media
ISBN: 364276150X
Category : Science
Languages : en
Pages : 606
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Book Description
A wide variety of hormones, neurotransmitters and growth factors exert their cellular effects by reacting first with membrane receptors resulting in an increase of intracellular calcium and the cellular response. The calcium signal in the cell is mediated by the high-affinity calcium binding proteins (characterized by the EF-hand structural element), and by the calcium and phospholipid dependent proteins. Many of these have been discovered most recently. Their purification, distribution, protein and gene structures as well as their physiological roles are discussed. The book is of interest to biochemists and molecular biologists as well as to clinicians and the pharmaceutical industry who can apply the results in this field.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 524
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author: Claus W. Heizmann
Publisher: Springer Science & Business Media
ISBN: 3662216892
Category : Medical
Languages : en
Pages : 167
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Book Description
This book summarizes the recent advances in the knowledge of the structure and physiological functions of the calcium-binding proteins in the central nervous system, describes their cellular distribution and developmental appearance, and discusses their possible association with neurodegenerative disorders and their use as diagnostic tools. This is the first book describing the structure, localization, and functions of calcium-binding proteins in the central nervous system and their involvement in neurodegenerative disorders. It is of great value to neurobiologists, clinicians, pharmacologists, biochemists and molecular biologists.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 968
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Book Description
Author: Joseph R. Lacowicz
Publisher: Springer Science & Business Media
ISBN: 0306471027
Category : Science
Languages : en
Pages : 320
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Book Description
The intrinsic or natural fluorescence of proteins is perhaps the most complex area of biochemical fluorescence. Fortunately the fluorescent amino acids, phenylalanine, tyrosine and tryptophan are relatively rare in proteins. Tr- tophan is the dominant intrinsic fluorophore and is present at about one mole % in protein. As a result most proteins contain several tryptophan residues and even more tyrosine residues. The emission of each residue is affected by several excited state processes including spectral relaxation, proton loss for tyrosine, rotational motions and the presence of nearby quenching groups on the protein. Additionally, the tyrosine and tryptophan residues can interact with each other by resonance energy transfer (RET) decreasing the tyrosine emission. In this sense a protein is similar to a three-particle or mul- particle problem in quantum mechanics where the interaction between particles precludes an exact description of the system. In comparison, it has been easier to interpret the fluorescence data from labeled proteins because the fluorophore density and locations could be controlled so the probes did not interact with each other. From the origins of biochemical fluorescence in the 1950s with Prof- sor G. Weber until the mid-1980s, intrinsic protein fluorescence was more qualitative than quantitative. An early report in 1976 by A. Grindvald and I. Z. Steinberg described protein intensity decays to be multi-exponential. Attempts to resolve these decays into the contributions of individual tryp- phan residues were mostly unsuccessful due to the difficulties in resolving closely spaced lifetimes.
Author:
Publisher:
ISBN:
Category : Calcium
Languages : en
Pages : 978
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Book Description
Author: Hiroshi Kawasaki
Publisher:
ISBN:
Category : Calcium
Languages : en
Pages : 212
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Book Description
Author: Oriol Bachs
Publisher: Springer Science & Business Media
ISBN: 3662216868
Category : Science
Languages : en
Pages : 173
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Book Description
This book is about the role of calcium and calmodulin in the cell nucleus. Calcium, which is an important second messenger of signal transduction pathways, can also operate in the cell nucleus. Different calcium binding proteins, which are the targets of cellular calcium, have been identified in the nucleus of many different cell types. Prominent among these calcium binding proteins is calmodulin, which appears to be involved in the regulation of major nuclear functions such as gene expression and DNA replication.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 2036
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Book Description
