The Science of Cancer

The Science of Cancer PDF Author: Scientific American Editors
Publisher: Scientific American
ISBN: 1466859075
Category : Medical
Languages : en
Pages : 225

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Book Description
The past few years have seen tremendous strides in our understanding of cancer, including new hypotheses about its genetic origins and new treatment alternatives using the body’s own immune response. In this eBook, The Science of Cancer, we examine what we know and what we’re finding out about this scourge of humankind. We delve into the molecular basis and complex causes of cancer, the arguments for and against screenings, new and targeted therapies, and minimizing risk. In “How Cancer Arises,” Robert Weinberg presents what has been the central dogma of cancer genetics, which says that a handful of essential mutations in specific genes lead to tumor growth; however, recent discoveries are challenging this theory, as we see in “Untangling the Roots of Cancer” and “Stem Cells: The Real Culprits in Cancer?” Early detection of cancer is important for treatment, but not all screening tests are created equal. In “The Great Prostate Cancer Debate,” Mark Garnick lays out the controversy over the value of the prostate-specific antigen test for prostate cancer and the rationale against screening. With our increasing knowledge of cancer’s causes, exciting targeted therapies are on the rise, including homing in on stem cells, making use of viruses, and manipulating the immune system as we see in “A New Ally against Cancer,” which focuses on treatment with therapeutic vaccines. Does this mean a cure is around the corner? Perhaps not, according to Scientific American Editor Dina Fine Maron in “Can We Truly ‘Cure’ Cancer?” But with remission rates rising for certain types of cancers and with new discoveries opening up further avenues of research, there is reason for optimism.

The Science of Cancer

The Science of Cancer PDF Author: Scientific American Editors
Publisher: Scientific American
ISBN: 1466859075
Category : Medical
Languages : en
Pages : 225

Get Book

Book Description
The past few years have seen tremendous strides in our understanding of cancer, including new hypotheses about its genetic origins and new treatment alternatives using the body’s own immune response. In this eBook, The Science of Cancer, we examine what we know and what we’re finding out about this scourge of humankind. We delve into the molecular basis and complex causes of cancer, the arguments for and against screenings, new and targeted therapies, and minimizing risk. In “How Cancer Arises,” Robert Weinberg presents what has been the central dogma of cancer genetics, which says that a handful of essential mutations in specific genes lead to tumor growth; however, recent discoveries are challenging this theory, as we see in “Untangling the Roots of Cancer” and “Stem Cells: The Real Culprits in Cancer?” Early detection of cancer is important for treatment, but not all screening tests are created equal. In “The Great Prostate Cancer Debate,” Mark Garnick lays out the controversy over the value of the prostate-specific antigen test for prostate cancer and the rationale against screening. With our increasing knowledge of cancer’s causes, exciting targeted therapies are on the rise, including homing in on stem cells, making use of viruses, and manipulating the immune system as we see in “A New Ally against Cancer,” which focuses on treatment with therapeutic vaccines. Does this mean a cure is around the corner? Perhaps not, according to Scientific American Editor Dina Fine Maron in “Can We Truly ‘Cure’ Cancer?” But with remission rates rising for certain types of cancers and with new discoveries opening up further avenues of research, there is reason for optimism.

Scientific American Molecular Oncology

Scientific American Molecular Oncology PDF Author: J. Michael Bishop
Publisher: Mosby Incorporated
ISBN: 9780894540233
Category : Medical
Languages : en
Pages : 255

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Book Description
This exciting new book approaches cancer diagnosis and therapy from the molecular level. It emphasizes the ability to isolate genes through the use of recombinant DNA. Full-color!

Scientific American Introduction to Molecular Medicine

Scientific American Introduction to Molecular Medicine PDF Author: Scientific American, inc
Publisher: Scientific American Medicine
ISBN: 9780894540158
Category : Medical
Languages : en
Pages : 348

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Book Description


Genes and the Biology of Cancer

Genes and the Biology of Cancer PDF Author: Harold Varmus
Publisher: Times Books
ISBN: 9780716750376
Category : Medical
Languages : en
Pages : 214

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Book Description
Discusses advances in cancer research and shows how research into the causes of cancer have led to a greater understanding of the normal biological functioning of cells

Scientific American

Scientific American PDF Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 572

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Book Description


Introduction to Molecular Medicine

Introduction to Molecular Medicine PDF Author: Dennis W. Ross
Publisher: Springer Science & Business Media
ISBN: 9780387953724
Category : Medical
Languages : en
Pages : 180

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Book Description
Presents the discoveries, basic scientific concepts, and sense of excitement that surround the revolution in molecular medicine. The scientific basis of molecular medicine is presented simply and directly, but at a level of technical detail sufficient for the reader to appreciate the power of recombinant DNA technology. The volume is clinically oriented throughout. Annotation copyrighted by Book News, Inc., Portland, OR

Molecular Oncology

Molecular Oncology PDF Author: Frank Joseph Rauscher (III)
Publisher: Cambridge University Press
ISBN: 0521876621
Category : Medical
Languages : en
Pages : 985

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Book Description
Reviews the origins of molecular oncology, including technologies for cancer analysis, key pathways in human malignancies, and available pharmacologic therapies.

The Basic Science of Oncology

The Basic Science of Oncology PDF Author: Ian Tannock
Publisher: McGraw Hill Professional
ISBN: 9780071387743
Category : Medical
Languages : en
Pages : 596

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Book Description
This concise text examines cancer causation and biology as well as the biology underlying cancer treatment. Thoroughly updated and reorganized with five new chapters, the Fourth Edition emphasizes new development in molecular biology, hormone therapy, and the pharmacology of anti-cancer drugs. Features updated coverage of the basic science of radiotherapy and experimental radiation in addition to expansive coverage of new drugs developments.

A Contagious Cause

A Contagious Cause PDF Author: Robin Wolfe Scheffler
Publisher: University of Chicago Press
ISBN: 022662837X
Category : Medical
Languages : en
Pages : 391

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Book Description
Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. ​ A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.

Evolution of Translational Omics

Evolution of Translational Omics PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309224187
Category : Science
Languages : en
Pages : 354

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Book Description
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.