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Author: James Njuguna
Publisher: Woodhead Publishing
ISBN: 0128205105
Category : Technology & Engineering
Languages : en
Pages : 537
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Book Description
The first edition of Health and Environmental Safety of Nanomaterials: Polymer Nanocomposites and Other Materials Containing Nanoparticles was published in 2014, but since that time, new developments in the field of nanomaterials safety have emerged, both at release and exposure, along with the expanding applications of the nanomaterials side. Numerous studies have been dedicated to the issue of biophysical interactions of nanoparticles with the human body at the organ, cellular, and molecular levels. In this second edition, all the chapters have been brought fully up to date. There are also four brand new chapters on the biophysical interaction of nanoparticles with the human body; advanced modeling approaches to help elucidate the nanorisks; safety measures at work with nanoparticles; and the health and environmental risks of graphene. It provides key knowledge and information needs for all those who are working in the research and development sector and need to learn more about the safety of nanomaterials. - Focuses on the health and safety of polymer nanocomposites and other materials containing nanoparticles, as well as their medical and environmental implications - Discusses the fundamental nature of various biophysical interactions of nanoparticles with the human body - Looks at the physico-chemistry of nanoparticles and their uptake, translocation, transformation, transport, and biodistribution in mammalian and plant systems - Presents the structure–activity relationships and modeling of the interactions of nanoparticles with biological molecules, biochemical pathways, analysis of biomolecular signatures, and the development of biomarkers
Author: James Njuguna
Publisher: Woodhead Publishing
ISBN: 0128205105
Category : Technology & Engineering
Languages : en
Pages : 537
Get Book Here
Book Description
The first edition of Health and Environmental Safety of Nanomaterials: Polymer Nanocomposites and Other Materials Containing Nanoparticles was published in 2014, but since that time, new developments in the field of nanomaterials safety have emerged, both at release and exposure, along with the expanding applications of the nanomaterials side. Numerous studies have been dedicated to the issue of biophysical interactions of nanoparticles with the human body at the organ, cellular, and molecular levels. In this second edition, all the chapters have been brought fully up to date. There are also four brand new chapters on the biophysical interaction of nanoparticles with the human body; advanced modeling approaches to help elucidate the nanorisks; safety measures at work with nanoparticles; and the health and environmental risks of graphene. It provides key knowledge and information needs for all those who are working in the research and development sector and need to learn more about the safety of nanomaterials. - Focuses on the health and safety of polymer nanocomposites and other materials containing nanoparticles, as well as their medical and environmental implications - Discusses the fundamental nature of various biophysical interactions of nanoparticles with the human body - Looks at the physico-chemistry of nanoparticles and their uptake, translocation, transformation, transport, and biodistribution in mammalian and plant systems - Presents the structure–activity relationships and modeling of the interactions of nanoparticles with biological molecules, biochemical pathways, analysis of biomolecular signatures, and the development of biomarkers
Author: Ramazan Asmatulu
Publisher: Newnes
ISBN: 0444594582
Category : Technology & Engineering
Languages : en
Pages : 257
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Book Description
Nanotechnology is a new and emerging discipline that is multidisciplinary and interdisciplinary. The usage of nanosystems, nanomaterials, nano-devices, etc. permeates all aspects of society. Cancer targeting and curing nanosystems are being introduced into the biomedical and pharmaceutical industries; so are lightweight energy absorbing or blast-proof nanohybrid material in the aerospace, automotive and marine industries and high-efficiency energy harvesting nanomaterials, etc. Society has a vested interest in knowing how these new materials, devices and systems are changing the economy and similar landscapes. The book outlines the regulatory and environmental issues related to nanotechnology per industry, offers guidelines in assessing the risks and discusses the legal and socioeconomical issues involved. Case studies will be utilized to provide examples of the positive and negative impacts of nanotechnology. - Provides an overview and the basis for understanding the critical importance of the reactivity and efficacy of nanomaterials and the emerging role of nanotechnology in society - Explains the fundamentals, ethics, regulatory and environmental issues of nanosafety and how they shape the emerging nanotechnology industry and markets and includes extensive lists of glossary terms, terminologies and concepts needed for Material Data Safety Sheets - Discusses the relevance and specificity of nanosafety issues per industry and includes discussions on the "Homeland Security and Infrastructure Industries" of interest to society in general - Includes nanotechnology risk assessment and delineates and quantifies the risk assessment process for nanotechnology safety of paramount importance to most industries and systems - Outlines the legal and intellectual property ramifications of nanotechnology and its impact on productivity and society
Author:
Publisher: Academic Press
ISBN: 0128165189
Category : Technology & Engineering
Languages : en
Pages : 316
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Book Description
Safety and Regulatory Issues of Nanoencapsulated Food Ingredients, a volume in the Nanoencapsulation in the Food Industry series, discusses the safety and toxicity potential of food-relevant and edible nanostructures, along with legislation issued by different countries and organizations governing their safety. The book's chapters cover safety issues of nanocapsules in food matrices, their possible toxicity effects, and in vitro and in vivo assays which are explored to underline their impact. Authored by a team of global experts in the fields of nano and microencapsulation of food, nutraceutical and pharmaceutical ingredients, this title is of great value to those engaged in fields surrounding nanoencapsulation. - Explores how to analyze the safety of nanoencapsulated bioactive ingredients - Discusses the regulations governing the safety of nanoencapsulated ingredients in different countries - Investigates what agencies and which governmental organizations are responsible for the safety of nanoencapsulated ingredients
Author: Shyamasree Ghosh
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110578360
Category : Science
Languages : en
Pages : 394
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Book Description
This monograph summarizes the current knowledge on potential health hazards induced by nanomaterials from different sources and sort such as food, drugs and silver nanoparticles. Methods to assess toxicity as well as known effects on the genome, neuronal and respiratory system are discussed. Besides the impact on human and animal life the books also addresses aquatic toxicity.
Author: Thomas J. Webster
Publisher: Springer Science & Business Media
ISBN: 0387786082
Category : Technology & Engineering
Languages : en
Pages : 245
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Book Description
In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first (if not the first) detailed views of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309253314
Category : Science
Languages : en
Pages : 230
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Book Description
The nanotechnology sector, which generated about $225 billion in product sales in 2009, is predicted to expand rapidly over the next decade with the development of new technologies that have new capabilities. The increasing production and use of engineered nanomaterials (ENMs) may lead to greater exposures of workers, consumers, and the environment, and the unique scale-specific and novel properties of the materials raise questions about their potential effects on human health and the environment. Over the last decade, government agencies, academic institutions, industry, and others have conducted many assessments of the environmental, health, and safety (EHS) aspects of nanotechnology. The results of those efforts have helped to direct research on the EHS aspects of ENMs. However, despite the progress in assessing research needs and despite the research that has been funded and conducted, developers, regulators, and consumers of nanotechnology-enabled products remain uncertain about the types and quantities of nanomaterials in commerce or in development, their possible applications, and their associated risks. A Research Strategy for Environmental, Health, and Safety Aspects of Engineered Nanomaterials presents a strategic approach for developing the science and research infrastructure needed to address uncertainties regarding the potential EHS risks of ENMs. The report summarizes the current state of the science and high-priority data gaps on the potential EHS risks posed by ENMs and describes the fundamental tools and approaches needed to pursue an EHS risk research strategy. The report also presents a proposed research agenda, short-term and long-term research priorities, and estimates of needed resources and concludes by focusing on implementation of the research strategy and evaluation of its progress, elements that the committee considered integral to its charge.
Author: Mahendra Rai
Publisher: John Wiley & Sons
ISBN: 1119769884
Category : Science
Languages : en
Pages : 452
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Book Description
NANOTECHNOLOGY IN MEDICINE Discover thorough insights into the toxicology of nanomaterials used in medicine In Nanotechnology in Medicine: Toxicity and Safety, an expert team of nanotechnologists delivers a robust and up-to-date review of current and future applications of nanotechnology in medicine with a special focus on neurodegenerative diseases, cancer, diagnostics, nano-nutraceuticals, dermatology, and gene therapy. The editors offer resources that address nanomaterial safety, which tends to be the greatest hurdle to obtaining the benefits of nanomedicine in healthcare. The book is a one-stop resource for recent and comprehensive information on the toxico logical and safety aspects of nanotechnology used in human health and medicine. It provides readers with cutting-edge techniques for delivering therapeutic agents into targeted cellular compartments, cells, tissues, and organs by using nanoparticulate carriers. The book also offers methodological considerations for toxicity, safety, and risk assessment. Nanotechnology in Medicine: Toxicity and Safety also provides readers with: A thorough introduction to the nanotoxicological aspects of nanomedicine, including translational nanomedicine and nanomedicine personalization Comprehensive introductions to nanoparticle toxicity and safety, including selenium nanoparticles and metallic nanoparticles Practical discussions of nanotoxicology and drug delivery, including gene delivery using nanocarriers and the use of nanomaterials for ocular delivery applications In-depth examinations of nanotechnology ethics and the regulatory framework of nanotechnology and medicine Perfect for researchers, post-doctoral candidates, and specialists in the fields of nanotechnology, nanomaterials, and nanocarriers, Nanotechnology in Medicine: Toxicity and Safety will also prove to be an indispensable part of the libraries of nanoengineering, nanomedicine, and biopharmaceutical professionals and nanobiotechnologists.
Author: Heather A. E. Benson
Publisher: John Wiley & Sons
ISBN: 1119769604
Category : Medical
Languages : en
Pages : 580
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Book Description
A comprehensive guide to the current research, major challenges, and future prospects of controlled drug delivery systems Controlled drug delivery has the potential to significantly improve therapeutic outcomes, increase clinical benefits, and enhance the safety of drugs in a wide range of diseases and health conditions. Fundamentals of Drug Delivery provides comprehensive and up-to-date coverage of the essential principles and processes of modern controlled drug delivery systems. Featuring contributions by respected researchers, clinicians, and pharmaceutical industry professionals, this edited volume reviews the latest research in the field and addresses the many issues central to the development of effective, controlled drug delivery. Divided in three parts, the book begins by introducing the concept of drug delivery and discussing both challenges and opportunities within the rapidly evolving field. The second section presents an in-depth critique of the common administration routes for controlled drug delivery, including delivery through skin, the lungs, and via ocular, nasal, and otic routes. The concluding section summarizes the current state of the field and examines specific issues in drug delivery and advanced delivery technologies, such as the use of nanotechnology in dermal drug delivery and advanced drug delivery systems for biologics. This authoritative resource: Covers each main stage of the drug development process, including selecting pharmaceutical candidates and evaluating their physicochemical characteristics Describes the role and application of mathematical modelling and the influence of drug transporters in pharmacokinetics and drug disposition Details the physiology and barriers to drug delivery for each administration route Presents a historical perspective and a look into the possible future of advanced drug delivery systems Explores nanotechnology and cell-mediated drug delivery, including applications for targeted delivery and toxicological and safety issues Includes comprehensive references and links to the primary literature Edited by a team of of internationally-recognized experts, Fundamentals of Drug Delivery is essential reading for researchers, industrial scientists, and advanced students in all areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.
Author: Chaudhery Mustansar Hussain
Publisher: John Wiley & Sons
ISBN: 1119592968
Category : Technology & Engineering
Languages : en
Pages : 597
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Book Description
This Handbook focuses on the recent advancements in Safety, Risk, Ethical Society and Legal Implications (ESLI) as well as its commercialization of nanotechnology, such as manufacturing. Nano is moving out of its relaxation phase of scientific route, and as new products go to market, organizations all over the world, as well as the general public, are discussing the environmental and health issues associated with nanotechnology. Nongovernmental science organizations have long since reacted; however, now the social sciences have begun to study the cultural portent of nanotechnology. Societal concerns and their newly constructed concepts, show nanoscience interconnected with the economy, ecology, health, and governance. This handbook addresses these new challenges and is divided into 7 sections: Nanomaterials and the Environment; Life Cycle Environmental Implications of Nanomanufacturing; Bioavailability and Toxicity of Manufactured Nanoparticles in Terrestrial Environments; Occupational Health Hazards of Nanoparticles; Ethical Issues in Nanotechnology; Commercialization of Nanotechnology; Legalization of Nanotechnology.
Author: Dominick E. Fazarro
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110386216
Category : Technology & Engineering
Languages : en
Pages : 228
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Book Description
Nanotechnology safety is the practice of handling engineered nanomaterials in production and manufacturing. Good practice consists of understanding and interpreting Material Safety Data Sheets, behaving safely when working with yet unknown nanomaterials, understanding health effects, and proactively creating safety measures against potential hazards. This book introduces nanotechnology risk management to readers from academia and industry.
