The Infectious Etiology of Chronic Diseases

The Infectious Etiology of Chronic Diseases PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309165911
Category : Medical
Languages : en
Pages : 234

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Book Description
In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children. The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine's Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.

The Infectious Etiology of Chronic Diseases

The Infectious Etiology of Chronic Diseases PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309165911
Category : Medical
Languages : en
Pages : 234

Get Book Here

Book Description
In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children. The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine's Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.

Case Studies in Pediatric Infectious Diseases

Case Studies in Pediatric Infectious Diseases PDF Author: Frank E. Berkowitz
Publisher: Cambridge University Press
ISBN: 1139465414
Category : Medical
Languages : en
Pages : 1

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Book Description
This book features 121 case studies intended to provide an approach to the diagnosis and treatment of pediatric infectious diseases. Brief clinical scenarios are followed by discussions and supplemented with tables and photographs. The author considers infections caused by a wide spectrum of viral, bacterial, fungal, and parasitic infectious agents, as well as those affecting specific anatomic sites. The author addresses both common infections and those presenting a greater challenge in diagnosis. Discussions focus on principles of management, as opposed to details, and place emphasis on determining risk factors and on clinical evaluation, not on performing non-discriminating laboratory tests. The introductory chapter addresses general principles for the diagnosis and management of infectious diseases. The appendix contains extensive tables and lists pertaining to infectious agents and their epidemiology. The book is illustrated with high-quality color photographs and radiographs. Its readability provides an engaging way to study pediatric infectious diseases.

Vascular Responses to Pathogens

Vascular Responses to Pathogens PDF Author: Felicity N.E. Gavins
Publisher: Academic Press
ISBN: 0128013257
Category : Medical
Languages : en
Pages : 254

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Book Description
Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. - Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature - Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field - Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature - Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs

Transient Ischemic Attack and Stroke

Transient Ischemic Attack and Stroke PDF Author: Sarah T. Pendlebury
Publisher: Cambridge University Press
ISBN: 0521735122
Category : Medical
Languages : en
Pages : 407

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Book Description
Accessible handbook covering the investigation, diagnosis and management of transient ischemic attacks and minor strokes.

Human Herpesviruses

Human Herpesviruses PDF Author: Ann Arvin
Publisher: Cambridge University Press
ISBN: 1139461648
Category : Medical
Languages : en
Pages : 1325

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Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Chronic Infection, Chlamydia and Coronary Heart Disease

Chronic Infection, Chlamydia and Coronary Heart Disease PDF Author: S. Gupta
Publisher: Springer Science & Business Media
ISBN: 0585375984
Category : Medical
Languages : en
Pages : 160

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Book Description
Coronary heart disease (CHD) remains a major cause of human mortality and morbidity worldwide. Classical risk factors for atherosclerosis fail to account fully for the wide variations in CHD prevalence and/or severity between differing populations. The search for hitherto unrecognised risk factors has recently focused on the potential role of chronic inflammation and common infections. Chronic Infection, Chlamydia and Coronary Heart Disease is the first book to review the wealth of evidence linking various infective agents with CHD, focusing particularly on the proposed pathogenetic role of the main candidate microorganism, Chlamydia pneumoniae. Written by two leading investigators in the field, the book provides a concise, clearly written and up-to-date account of the diverse lines of evidence - seroepidemiological, pathological, animal and in vitro data and clinical antibiotic trials. The possibility of an infective basis to atherosclerosis and CHD has already attracted much scientific interest. Chronic Infection, Chlamydia and Coronary Heart Disease highlights the key published works on the topic, and concludes with information on existing, ongoing, and future lines of enquiry.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease PDF Author: Robert Fitridge
Publisher: University of Adelaide Press
ISBN: 1922064009
Category : Medical
Languages : en
Pages : 589

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Book Description
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Inflammation and Atherosclerosis

Inflammation and Atherosclerosis PDF Author: Georg Wick
Publisher: Springer Science & Business Media
ISBN: 370910338X
Category : Medical
Languages : en
Pages : 628

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Book Description
It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.

Pathology of the Lungs E-Book

Pathology of the Lungs E-Book PDF Author: Bryan Corrin
Publisher: Elsevier Health Sciences
ISBN: 0702046221
Category : Medical
Languages : en
Pages : 785

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Book Description
With an emphasis on practical diagnostic problem solving, Pathology of the Lungs, 3rd Edition provides the pulmonary pathologist and the general surgical pathologist with an accessible, comprehensive guide to the recognition and interpretation of common and rare neoplastic and non-neoplastic lung conditions. The text is written by two authors and covers all topics in a consistent manner without the redundancies or lapses that are common in multi-authored texts. The text is lavishly illustrated with the highest quality illustrations which accurately depict the histologic, immunohistochemical and cytologic findings under consideration and it is supplemented throughout with practical tips and advice from two internationally respected experts. The user-friendly design and format allows rapid access to essential information and the incorporation throughout of relevant clinical and radiographic information makes it a complete diagnostic resource inside the reporting room. Approximately 1,000 high quality full color illustrations.Provides the user with a complete visual guide to each specimen and assists in the recognition and diagnosis of any slide looked at under the microscope. Comprehensive coverage of both common and rare lung diseases and disorders. One stop consultation resource for the reporting room or study, no need to go further to get questions answered. Clinical background and ancillary radiographs incorporated throughout.Provides the user with all of the necessary diagnostic tools to make a complete and accurate pathologic report. Practical advice and tips from two of the world’s recognized experts. Provides the trainee and general surgical pathologist with time saving diagnostic clues when dealing with difficult specimens. Consistent and uniform approach incorporated for each disease and disorder (Etiology, pathogenesis, clinical features, pathologic features, differential diagnosis) User-friendly format enables quick and easy navigation to the key information required. Extensive use of summary tables, charts and graphs throughout the text. Helps simplify and clarify complex concepts and facilitates “at a glance comparisons between entities. Extensive reference list highlights landmark articles as well as including most up-to-date citations. Directs the trainee and practitioner to the most recent and authoritative sources for further reading and investigation

Infections in Pregnancy

Infections in Pregnancy PDF Author: Adel Elkady
Publisher: Cambridge University Press
ISBN: 1108716636
Category : Medical
Languages : en
Pages : 215

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Book Description
Provides effective diagnosis and management of infectious diseases in pregnant women in a single comprehensive available resource for busy clinicians.