Author: Matthew M. LaVail
Publisher: Springer Science & Business Media
ISBN: 1461406315
Category : Medical
Languages : en
Pages : 867
Get Book Here
Book Description
This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.
Author: Marco A. Zarbin
Publisher: Springer
ISBN: 3030052222
Category : Science
Languages : en
Pages : 286
Get Book Here
Book Description
This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.
Author: Jay Chhablani
Publisher: Academic Press
ISBN: 0128092238
Category : Science
Languages : en
Pages : 474
Get Book Here
Book Description
Choroidal Disorders provides an overview on various chorioretinal disorders with a special emphasis on choroidal imaging. As our understanding of the choroid has significantly improved with the development of advanced optical coherence tomography (OCT) and its role in posterior segment diseases is gaining new significance, this book focuses on the related improvements, diagnostic capabilities, management and prognosis of various chorioretinal disorders. It covers conventional techniques, such as ultrasonography and indocyanine green angiography as well as the most advanced techniques, including enhanced depth imaging OCT, swept source OCT, and OCT angiography. - Concise overview of various chorioretinal disorders, with special emphasis on choroidal imaging - Written for practitioners and researchers in sensory systems (vision), ophthalmologists, and retina specialists - Covers the most advanced imaging techniques in choroidal disorders, such as enhanced depth imaging OCT, swept source OCT, and OCT angiography
Author: Glenn Prazere Lobo
Publisher: Frontiers Media SA
ISBN: 2889667022
Category : Science
Languages : en
Pages : 162
Get Book Here
Book Description
Author: Helga Kolb
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Author: Keith M. Zinn
Publisher: Springer Science & Business Media
ISBN: 1461237203
Category : Medical
Languages : en
Pages : 164
Get Book Here
Book Description
A comprehensive understanding of diseases of the peripheral retina is essential to the general ophthalmologist as well as to the vitreoretinal surgeon. Expertise in in direct ophthalmoscopy, scleral depression, and contact lens biomicroscopy serves as a basis for observing the peripheral retina. These observations are then re corded on fundus drawing paper and the Tolentino vitreo-retinal chart. This or derly sequence of skills allows the ophthalmic surgeon to objectively diagnose and evaluate specific peripheral retinal disorders and plan for their therapeutic management. The Clinical Atlas of Peripheral Retinal Disorders is a compilation of fundus paint ings by David A. Tilden based on our observations of a large number of patients over the past 15 years. The atlas is organized along functional and anatomical lines. After a brief introduction to the clinical anatomy of the peripheral retina, the appearance of the fundus as a function of skin color and aging is presented. Many of the diseases of the peripheral retina can be divided into trophic (nutritional), tractional, and a combination of trophic plus tractional etiologies. This classifica tion system, although somewhat simplistic, appears adequate for our present level of understanding of the pathogenetic mechanisms of these disorders. Un doubtedly, once the molecular biology of these conditions is elucidated through future research, the classification will be revised. In addition, there are other con ditions that affect the peripheral retina that do not fit the proposed classification system and are covered under separate headings, i. e.
Author: Matthew M. LaVail
Publisher: Springer Science & Business Media
ISBN: 1461500672
Category : Medical
Languages : en
Pages : 458
Get Book Here
Book Description
The topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration. Special focus is highlighted in the areas of Mechanisms of Photoreceptor Degeneration and Cell Death (extremely important because very little is known how or why photoreceptors die in these diseases, despite an abundance of genetic information), Age-Related Macular Degeneration (with several novel approaches to its analysis), Usher Syndrome (the most severe form of retinitis pigmentosa, which includes an early or congenital loss of hearing along with blindness), and Gene Therapy. In addition, the section on Basic Science Related to Retinal Degeneration is particularly strong with several laboratories reporting on new discoveries in the area of outer segment phagocytosis, a key component of photoreceptor-retinal pigment epithelial cell interactions in normal and degenerating retinas.
Author: Maurice Ptito
Publisher: Mdpi AG
ISBN: 9783036526539
Category : Science
Languages : en
Pages : 498
Get Book Here
Book Description
Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.
Author: Elias I. Traboulsi
Publisher: OUP USA
ISBN: 0195326148
Category : Medical
Languages : en
Pages : 940
Get Book Here
Book Description
This book takes a clinical approach to the patient with a genetic disease that affects the eye. The chapters on particular types of diseases follow the same organizational format, covering history, pathogenesis and etiology, epidemiology, classification, clinical manifestations and diagnosis, and treatment. The recent progress achieved in the molecular genetics of eye disease is fully reflected throughout the book. It is written by leading experts in the field and provides clinical, molecular genetic and management information on common and rare diseases. The chapters are heavily illustrated and provide a good Atlas for the practicing ophthalmologist or geneticist.
Author: Charles P. Wilkinson
Publisher: Elsevier Health Sciences
ISBN: 0323401988
Category : Medical
Languages : en
Pages : 2893
Get Book Here
Book Description
The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology.
