International Review of Cytology

International Review of Cytology PDF Author: Kwang W. Jeon
Publisher: Academic Press
ISBN: 0123646456
Category : Medical
Languages : en
Pages : 333

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Book Description
International Review of Cytology presents current advances and comprehensive reviews in cell biology - both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address biosynthesis and alternate targeting of the lysosomal cysteine protesase cathepsin L; microtubule-associated proteins and their essential roles during mitosis; molecular and functional analysis of the dictyostelium centrosome; polytene chromosomes; and insect basic leucine zipper proteins and their role in cyclic AMP dependent regulation of gene expression.

International Review of Cytology

International Review of Cytology PDF Author: Kwang W. Jeon
Publisher: Academic Press
ISBN: 0123646456
Category : Medical
Languages : en
Pages : 333

Get Book Here

Book Description
International Review of Cytology presents current advances and comprehensive reviews in cell biology - both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address biosynthesis and alternate targeting of the lysosomal cysteine protesase cathepsin L; microtubule-associated proteins and their essential roles during mitosis; molecular and functional analysis of the dictyostelium centrosome; polytene chromosomes; and insect basic leucine zipper proteins and their role in cyclic AMP dependent regulation of gene expression.

An Introduction to Ecological Genomics

An Introduction to Ecological Genomics PDF Author: Nico M. van Straalen
Publisher: Oxford University Press
ISBN: 0199594686
Category : Science
Languages : en
Pages : 374

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Book Description
The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models.

PAS Proteins: Regulators and Sensors of Development and Physiology

PAS Proteins: Regulators and Sensors of Development and Physiology PDF Author: Stephen T. Crews
Publisher: Springer Science & Business Media
ISBN: 9781402075865
Category : Science
Languages : en
Pages : 292

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Book Description
PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status. Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders, and (6) mental health disorders such as social interactions and learning. PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.

Handbook of Epigenetics

Handbook of Epigenetics PDF Author: Trygve Tollefsbol
Publisher: Academic Press
ISBN: 012375710X
Category : Science
Languages : en
Pages : 639

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Book Description
Epigenetics is considered by many to be the "new genetics" because of the overwhelming evidence of the contribution of non-genetic factors such as nutrition, environment, and chemical exposure on gene expression. The effects of epigenetics are vast, including tissue/organ regeneration, X-chromosome inactivation, and stem cell differentiation and genomic imprinting and aging. Aberrations of epigenetics influence many diseases for which clinical intervention is already in place, and many novel epigenetic therapies for cancer, immune disorders, neurological and metabolic disorders, and imprinting diseases are on the horizon. This comprehensive collection of reviews written by leaders in the field of epigenetics provides a broad view of this important and evolving topic. From molecular mechanisms and epigenetic technology to discoveries in human disease and clinical epigenetics, the nature and applications of the science will be presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders. Contributions by leading international investigators involved in molecular research and clinical and therapeutic applications Integrates methods and biological topics with basic and clinical discoveries Includes coverage of new topics in epigenetics such as prions, regulation of long-term memory by epigenetics, metabolic aspects of epigenetics, and epigenetics of neuronal disorders

Introduction to Epigenetics

Introduction to Epigenetics PDF Author: Renato Paro
Publisher: Springer Nature
ISBN: 3030686701
Category : Science
Languages : en
Pages : 215

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Book Description
This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

Pattern Formation in Zebrafish

Pattern Formation in Zebrafish PDF Author: Lilianna Solnica-Krezel
Publisher: Springer Science & Business Media
ISBN: 3540460411
Category : Science
Languages : en
Pages : 452

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Book Description
Authored by leading experts in the field, this book provides the first comprehensive overview of the mechanisms of early patterning and morphogenesis in zebrafish. It summarizes the current knowledge and the key questions for the next decade of research.

Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1354

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Book Description


Human Genetic Diseases

Human Genetic Diseases PDF Author: Dijana Plaseska-Karanfilska
Publisher: BoD – Books on Demand
ISBN: 9533079363
Category : Medical
Languages : en
Pages : 302

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Book Description
The genetics science is less than 150 years old, but its accomplishments have been astonishing. Genetics has become an indispensable component of almost all research in modern biology and medicine. Human genetic variation is associated with many, if not all, human diseases and disabilities. Nowadays, studies investigating any biological process, from the molecular level to the population level, use the "genetic approach" to gain understanding of that process. This book contains many diverse chapters, dealing with human genetic diseases, methods to diagnose them, novel approaches to treat them and molecular approaches and concepts to understand them. Although this book does not give a comprehensive overview of human genetic diseases, I believe that the sixteen book chapters will be a valuable resource for researchers and students in different life and medical sciences.

Index Medicus

Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1666

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Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

RNA Exosome

RNA Exosome PDF Author: Torben Heick Jensen
Publisher: Springer Science & Business Media
ISBN: 1441978410
Category : Medical
Languages : en
Pages : 161

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Book Description
The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.