Recent Results in Cancer Research. Vol. 11 PDF Download
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Author:
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Languages : en
Pages :
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Author:
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Category :
Languages : en
Pages :
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Author: Norman E. Breslow
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 352
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Author: Pierre Rentchnick
Publisher:
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Category : Cancer
Languages : en
Pages : 142
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Author: Ole Møller Jensen
Publisher: IARC
ISBN: 9283211952
Category : Medical
Languages : en
Pages : 295
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Book Description
Data obtained by population based cancer registries have a pivotal role in cancer control. Now also available in Spanish and French, this volume, which contains 15 authored chapters and four useful appendices, remains a standard reference for those planning to establish new cancer registries and those keen to adopt recognized methodologies. Information is given on the techniques required to collect, store, analyse and interpret data.
Author: Michail Ignatiadis
Publisher: Springer Science & Business Media
ISBN: 3642281605
Category : Medical
Languages : en
Pages : 245
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Book Description
This important book provides up-to-date information on a series of topical issues relating to the approach to minimal residual disease in breast cancer patients. It first explains how the study of minimal residual disease and circulating and disseminated tumor cells (CTCs/DTCs) can assist in the understanding of breast cancer metastasis. A series of chapters then discuss the various technologies available for the detection and characterization of CTCs and DTCs, pinpointing their merits and limitations. Detailed consideration is given to the relevance of CTCs and DTCs, and their detection, to clinical research and practice. The role of other blood-based biomarkers is also addressed, and the closing chapters debate the challenges facing drug and biomarker co-development and the use of CTCs for companion diagnostic development. This book will be of interest and assistance to all who are engaged in the modern management of breast cancer.
Author:
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Category : Cancer
Languages : en
Pages : 204
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Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1118
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Category : Cancer
Languages : en
Pages : 672
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Category : Age factors in disease
Languages : en
Pages : 232
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Author: H. Acker
Publisher: Springer Science & Business Media
ISBN: 3642823408
Category : Medical
Languages : en
Pages : 328
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Book Description
Malignant growth of cells is often characterized by disorganization of tissue structure, abnormal blood vessel development, and insuffi cient vascular supply. As a consequence, the cancer cells grow in a three-dimensional pattern in atypical microenvironments which include physical, chemical, and nutritional stresses. Necrosis often develops some distance away from the blood vessels. In association with an inherent instability in malignant cell populations, and also because of the changing micromilieu, significant cellular heteroge neity emerges with regard to various phenotypic characteristics. Both biological behavior and responses to therapeutic agents can be affected. A variety of in vitro and in vivo experimental models exist for research on properties of cancer cells during growth. The multicell spheroid model was developed as a system of intermediate complexity in which three dimensional growth of cells enhances cell-cell interactions and creates micro environments that simulate the conditions in intervascular microregions of tumors or microme tastatic foci. Spheroids may change their cellular characteristics with changing environments during growth. These can be studied under controlled conditions in vitro. Interest in details of experimental methods for this model system stimulated the organization of the First International Conference in Rochester, NY in 1980, the Proceedings of which were summarized in Cancer Research in 1981. Since then there has been a rapid increase in the use of this model system, and increased research on the significance of cell-cell and cell-microenvironment interactions in biology in general.
