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Author: Bert Fraser-Reid
Publisher: Springer Science & Business Media
ISBN: 3642209130
Category : Science
Languages : en
Pages : 309
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Book Description
Armed–Disarmed Effects in Carbohydrate Chemistry: History, Synthetic and Mechanistic Studies, by Bert Fraser-Reid and J. Cristóbal López * A Survey of Ley’s Reactivity Tuning in Oligosaccharide Synthesis, by Ana M. Gómez * “Active–Latent” Thioglycosyl Donors and Acceptors in Oligosaccharide Syntheses, by Tze Chieh Shiao and René Roy * Effect of Electron-Withdrawing Protecting Groups at Remote Positions of Donors on Glycosylation Stereochemistry, by Kwan Soo Kim and Dae-Hwan Suk * Influence of Protecting Groups on the Reactivity and Selectivity of Glycosylation: Chemistry of the 4,6-O-Benzylidene Protected Mannopyranosyl Donors and Related Species, by Sylvain Aubry, Kaname Sasaki, Indrajeet Sharma and David Crich * Superarmed and Superdisarmed Building Blocks in Expeditious Oligosaccharide Synthesis, by Hemali D. Premathilake and Alexei V. Demchenko * Programmable One-Pot Glycosylation, by Chung -Yi Wu and Chi -Huey Wong * Uronic Acids in Oligosaccharide and Glycoconjugate Synthesis, by Jeroen D. C. Codée, Alphert E. Christina, Marthe T. C. Walvoort, Herman S. Overkleeft and Gijsbert A. van der Marel
Author: Bert Fraser-Reid
Publisher: Springer Science & Business Media
ISBN: 3642209130
Category : Science
Languages : en
Pages : 309
Get Book Here
Book Description
Armed–Disarmed Effects in Carbohydrate Chemistry: History, Synthetic and Mechanistic Studies, by Bert Fraser-Reid and J. Cristóbal López * A Survey of Ley’s Reactivity Tuning in Oligosaccharide Synthesis, by Ana M. Gómez * “Active–Latent” Thioglycosyl Donors and Acceptors in Oligosaccharide Syntheses, by Tze Chieh Shiao and René Roy * Effect of Electron-Withdrawing Protecting Groups at Remote Positions of Donors on Glycosylation Stereochemistry, by Kwan Soo Kim and Dae-Hwan Suk * Influence of Protecting Groups on the Reactivity and Selectivity of Glycosylation: Chemistry of the 4,6-O-Benzylidene Protected Mannopyranosyl Donors and Related Species, by Sylvain Aubry, Kaname Sasaki, Indrajeet Sharma and David Crich * Superarmed and Superdisarmed Building Blocks in Expeditious Oligosaccharide Synthesis, by Hemali D. Premathilake and Alexei V. Demchenko * Programmable One-Pot Glycosylation, by Chung -Yi Wu and Chi -Huey Wong * Uronic Acids in Oligosaccharide and Glycoconjugate Synthesis, by Jeroen D. C. Codée, Alphert E. Christina, Marthe T. C. Walvoort, Herman S. Overkleeft and Gijsbert A. van der Marel
Author: Helen Osborn
Publisher: Academic Press
ISBN: 008052852X
Category : Science
Languages : en
Pages : 453
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Book Description
There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows the practising synthetic chemist to choose between all the alternatives and assess their real advantages and limitations. Each chapter in Carbohydrates details a particular theme associated with carbohydrate synthesis. A brief review of the subject area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. In order for the roles of carbohydrates to be thoroughly analysed and assessed, glycobiologists require access to defined target carbohydrates in useful quantities. Thus carbohydrates and glycoconjugates are now recognized as important targets for total synthesis programmes and it is essential to develop efficient regio- and stereoselective methods for the synthesis of carbohydrates. Whilst carbohydrates can sometimes be isolated from natural sources, synthetic strategies often offer the advantage of allowing access to larger quantities of material as well as entry to analogues of the natural carbohydrates. - The latest volume in the long standing Best Synthetic Methods series - Clear chapter by chapter breakdown of carbohydrate synthesis themes with examples of good practical methods for common carbohydrate syntheses
Author: Tommaso Bellini
Publisher: Springer Science & Business Media
ISBN: 3642275907
Category : Science
Languages : en
Pages : 419
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Book Description
Fluorinated Liquid Crystals: Design of Soft Nanostructures and Increased Complexity of Self-Assembly by Perfluorinated Segments, by Carsten Tschierske Liquid Crystalline Crown Ethers, by Martin Kaller and Sabine Laschat Star-Shaped Mesogens – Hekates: The Most Basic Star Structure with Three Branches, by Matthias Lehmann DNA-Based Soft Phases, by Tommaso Bellini, Roberto Cerbino and Giuliano Zanchetta Polar and Apolar Columnar Phases Made of Bent-Core Mesogens, by N. Vaupotič, D. Pociecha and E. Gorecka Spontaneous Achiral Symmetry Breaking in Liquid Crystalline Phases, by H. Takezoe Nanoparticles in Liquid Crystals and Liquid Crystalline Nanoparticles, by Oana Stamatoiu, Javad Mirzaei, Xiang Feng and Torsten Hegmann Stimuli-Responsive Photoluminescent Liquid Crystals, by Shogo Yamane, Kana Tanabe, Yoshimitsu Sagara and Takashi Kato
Author: Xuefeng Jiang
Publisher: Springer Nature
ISBN: 3030255980
Category : Science
Languages : en
Pages : 477
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Book Description
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Author: Laura Cipolla
Publisher: World Scientific
ISBN: 1783267216
Category : Science
Languages : en
Pages : 535
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Book Description
The structural complexity and the synthetic challenges facing glycans have historically hampered efforts to study their multifaceted roles and the application of carbohydrates in drug development. However, in very recent years, new synthetic techniques flanked by the growing knowledge about carbohydrate involvement in physiological and pathological states has spurred renewed interest in the chemistry, biology and therapeutic potentialities of carbohydrates. This book offers an overview of key aspects of carbohydrate biology and chemistry that are fundamental for the design of novel therapeutics. The four-part structure of this book introduces these essential components to life, starting from their structure and biological roles and covering analytical methods and synthesis which pave the way for the development of a wide range of therapeutic applications.Leading experts from around the world are brought together to offer their recent research with the ultimate aim of enlightening the reader on the complex yet exciting field of carbohydrate chemistry. Academic and industrial researchers in structural biology, drug discovery and carbohydrate chemistry will find this book an essential guide to the latest research and future potential of medicinal chemistry.
Author: Igor Alabugin
Publisher: American Chemical Society
ISBN: 0841299633
Category : Science
Languages : en
Pages : 283
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Book Description
Although carbon is considered the central element of organic chemistry, the broader chemical world has one more star player—oxygen. Billions of years of evolution have filled your room with oxygen as countless cyanobacteria and plants work on changing our planet. Oxygen is everywhere—from geology to biology, from the Earth's crust to the ozone layer. This digital primer aims to analyze chemical reactivity through the prism of oxygen chemistry. The key to understanding this chemistry is the lone pairs of oxygen (i.e., the underutilized "idle" electrons that do not directly contribute to the Lewis structure of molecules). By highlighting the many roles of oxygen, we will illustrate how chemistry rises above the limitations of Lewis structures and how electrons stay neither idle nor "lone" even if they are in "lone pairs" when an oxygen atom is near a reaction center. This digital primer will introduce important types of chemical bonding that transcend undergraduate textbooks but that are likely to drive the development of new chemical reactions in the future.
Author: Markus Albrecht
Publisher: Springer Science & Business Media
ISBN: 3642280595
Category : Science
Languages : en
Pages : 183
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Book Description
Molecular Cages and Capsules with Functionalized Inner Surfaces, by Stefan Kubik. Drug Delivery by Water-Soluble Organ metallic Cages, by Bruno Therrien. Reversibly Expanded Encapsulation Complexes, by Dariush Ajami und Julius Rebek. Container Molecules Based on Imine Type Ligands, by A. Carina Schulze und Iris M. Oppel. Molecular Capsules Derived from Resorcin[4]arenes by Metal-Coordination, by Tobias Schröder, Satya Narayan Sahu und Jochen Mattay. Coronates, Spherical Containers, Bowl-Shaped Surfaces, Porous 1D-, 2D-, 3D-Metallo-Coordination Polymers, and Metallodendrimers, by Rolf W. Saalfrank und Andreas Scheurer.
Author: Sebastien Vidal
Publisher: John Wiley & Sons
ISBN: 3527340106
Category : Science
Languages : en
Pages : 522
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Book Description
A unique overview of the most important protecting group strategies in carbohydrate chemistry Protecting Groups: Strategies and Applications in Carbohydrate Chemistry provides a detailed account of key strategies and methodologies for the protection of carbohydrates. Divided into two parts, the first focuses on groups that are used best to protect a specific position on a carbohydrate. In the second part, specific carbohydrate residues or compounds are discussed in the context of a specific protecting group strategy used to reach the desired regioisomer. This important book: -Features chapters on protecting groups at the primary and secondary positions of carbohydrates -Describes protecting group strategies towards sialic acid derivatives, glycofuranoses, sulfated glycosaminoglycans, and cyclodextrins -Provides information on automated glycan assembly -Includes a chapter on the industrial scale synthesis of heparin analogs Written by a team of leaders in the field, Protecting Groups: Strategies and Applications in Carbohydrate Chemistry is an indispensable guide for academics and industrial researchers interested in carbohydrate and natural product synthesis, pharmaceutical chemistry, and biochemistry.
Author: Clay S. Bennett
Publisher: John Wiley & Sons
ISBN: 3527339876
Category : Science
Languages : en
Pages : 403
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Book Description
A comprehensive summary of novel approaches to the stereoselective construction of glycosidic linkages, covering modern glycosylation methods and their use and application in natural product synthesis and drug discovery. Clearly divided into five sections, the first describes recent advances in classical methodologies in carbohydrate chemistry, while the second goes on to deal with newer chemistries developed to control selectivity in glycosylation reactions. Section three is devoted to selective glycosylation reactions that rely on the use of catalytic promoters. Section four describes modern approaches for controlling regioselectivity in carbohydrate synthesis. The final section focuses on new developments in the construction of "unusual" sugars and is rounded off by a presentation of modern procedures for the construction of glycosylated natural products. By providing the latest advances in glycosylation as well as information on mechanistic aspects of the reaction, this is an invaluable reference for both specialists and beginners in this booming interdisciplinary field that includes carbohydrate chemistry, organic synthesis, catalysis, and biochemistry.
Author: Bert Fraser-Reid
Publisher: Springer Science & Business Media
ISBN: 3642227813
Category : Science
Languages : en
Pages : 224
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Book Description
More than just coincidence connects a Tate & Lyle lawsuit and artificial sweetener to Jamaican-born Chemist Bert Fraser-Reid. From his first experience of Chemistry through his diabetic father, to his determination and drive as a Chemistry student in Canada, Fraser-Reid weaves a remarkable tale integrating science, law and autobiographical anecdotes. This book arises from the lawsuit brought by Tate & Lyle against companies accused of infringing its patents for sucralose, the sweet ingredient in the artificial sweetener SPLENDA which is made by chlorinating sugar. From a 1958 undergraduate intern witnessing the pioneering experiments on sugar chlorination, to being the 1991 recipient of the world’s premiere prize for carbohydrate chemistry, Fraser-Reid was groomed for his role as expert witness in the mentioned lawsuit. Nevertheless, it seems more than his career links Fraser-Reid to the case.
