Author: Angela Heiser
Publisher: Springer
ISBN: 9780387494142
Category : Science
Languages : en
Pages : 116
Book Description
Jugular vein and carotid artery cannulations are among the most widely used surgeries in research labs around the world. This book features two cannulation procedures detailed in a format of materials, instruction, and pictorial for each step. In addition, it also details procedures for anesthesia, pre- and post- operatives, anatomy, bleeding techniques using catheters implanted, and rat biodata compiled from numerous sources.
Rat Jugular Vein and Carotid Artery Catheterization for Acute Survival Studies
Author: Angela Heiser
Publisher: Springer
ISBN: 9780387494142
Category : Science
Languages : en
Pages : 116
Book Description
Jugular vein and carotid artery cannulations are among the most widely used surgeries in research labs around the world. This book features two cannulation procedures detailed in a format of materials, instruction, and pictorial for each step. In addition, it also details procedures for anesthesia, pre- and post- operatives, anatomy, bleeding techniques using catheters implanted, and rat biodata compiled from numerous sources.
Publisher: Springer
ISBN: 9780387494142
Category : Science
Languages : en
Pages : 116
Book Description
Jugular vein and carotid artery cannulations are among the most widely used surgeries in research labs around the world. This book features two cannulation procedures detailed in a format of materials, instruction, and pictorial for each step. In addition, it also details procedures for anesthesia, pre- and post- operatives, anatomy, bleeding techniques using catheters implanted, and rat biodata compiled from numerous sources.
Rat Jugular Vein and Carotid Artery Catheterization for Acute Survival Studies
Author: Angela Heiser
Publisher: Springer Science & Business Media
ISBN: 0387494162
Category : Science
Languages : en
Pages : 123
Book Description
Jugular vein and carotid artery cannulations are among the most widely used surgeries in research labs around the world. This book features two cannulation procedures detailed in a format of materials, instruction, and pictorial for each step. In addition, it also details procedures for anesthesia, pre- and post- operatives, anatomy, bleeding techniques using catheters implanted, and rat biodata compiled from numerous sources.
Publisher: Springer Science & Business Media
ISBN: 0387494162
Category : Science
Languages : en
Pages : 123
Book Description
Jugular vein and carotid artery cannulations are among the most widely used surgeries in research labs around the world. This book features two cannulation procedures detailed in a format of materials, instruction, and pictorial for each step. In addition, it also details procedures for anesthesia, pre- and post- operatives, anatomy, bleeding techniques using catheters implanted, and rat biodata compiled from numerous sources.
The Care and Feeding of an IACUC
Author: Whitney Kayla Petrie
Publisher: CRC Press
ISBN: 1040072518
Category : Medical
Languages : en
Pages : 286
Book Description
Maintaining its user-friendly approach, this new edition of a bestseller summarizes information necessary for the effective and efficient operation of an IACUC. The book covers training programs and discusses professional certifications for IACUC administrative and animal care staff. It provides pointers to principal investigators, discusses interactions between IACUCs and other compliance panels, and addresses occupational health and safety programs and the role they play in the overall animal care and use program. It also delves deeply into bioethics to explore how IACUCs can ensure that each proposal to use animals in research includes an ethical review.
Publisher: CRC Press
ISBN: 1040072518
Category : Medical
Languages : en
Pages : 286
Book Description
Maintaining its user-friendly approach, this new edition of a bestseller summarizes information necessary for the effective and efficient operation of an IACUC. The book covers training programs and discusses professional certifications for IACUC administrative and animal care staff. It provides pointers to principal investigators, discusses interactions between IACUCs and other compliance panels, and addresses occupational health and safety programs and the role they play in the overall animal care and use program. It also delves deeply into bioethics to explore how IACUCs can ensure that each proposal to use animals in research includes an ethical review.
Translational Neuroscience
Author: Mark H. Tuszynski
Publisher: Springer
ISBN: 148997654X
Category : Medical
Languages : en
Pages : 584
Book Description
Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging yet detailed sample of many of these efforts, together with the methods for pursuing clinical translation and assessing clinical outcomes. Among the topics covered are Alzheimer’s disease, Parkinson’s disease, stroke, multiple sclerosis, epilepsy, motor neuron disease, pain, inborn errors of metabolism, brain tumors, spinal cord injury, neuroprosthetics, rehabilitation and clinical trial design/consideration. Translational Neuroscience is aimed at basic neuroscientists, translational neuroscientists and clinicians who seek to gain a perspective on the nature and promise of translational therapies in the current era. Both students and established professionals will benefit from the content.
Publisher: Springer
ISBN: 148997654X
Category : Medical
Languages : en
Pages : 584
Book Description
Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging yet detailed sample of many of these efforts, together with the methods for pursuing clinical translation and assessing clinical outcomes. Among the topics covered are Alzheimer’s disease, Parkinson’s disease, stroke, multiple sclerosis, epilepsy, motor neuron disease, pain, inborn errors of metabolism, brain tumors, spinal cord injury, neuroprosthetics, rehabilitation and clinical trial design/consideration. Translational Neuroscience is aimed at basic neuroscientists, translational neuroscientists and clinicians who seek to gain a perspective on the nature and promise of translational therapies in the current era. Both students and established professionals will benefit from the content.
Oral Bioavailability
Author: Xiaoling Li
Publisher: John Wiley & Sons
ISBN: 1118067584
Category : Medical
Languages : en
Pages : 875
Book Description
Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help chemists, biologists, life science researchers, pharmaceutical scientists, pharmacologists, clinicians, and graduate and students become familiar with the fundamentals and practices of the science of oral bioavailability. The difference in rate and extent between a drug taken orally and the actual amount of a drug reaching the circulatory system, oral bioavailability is an essential parameter for determining the efficacy and adverse effects of new and developing medications, as well as finding an optimal dosing regimen. This book provides a much-needed one-stop resource to help readers better understand and appreciate the many facets and complex problems of oral bioavailability, including the basic barriers to oral bioavailability, the methods used to determine relevant parameters, and the challenges of drug delivery. In addition, this comprehensive book discusses biological and physicochemical methods for improving bioavailability, integrates physicochemistry with physiology and molecular biology, and includes several state-of-the-art technologies and approaches Caco-2 cell culture model, MDCK, and other related cell culture models which are used to study the science of oral bioavailability.
Publisher: John Wiley & Sons
ISBN: 1118067584
Category : Medical
Languages : en
Pages : 875
Book Description
Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help chemists, biologists, life science researchers, pharmaceutical scientists, pharmacologists, clinicians, and graduate and students become familiar with the fundamentals and practices of the science of oral bioavailability. The difference in rate and extent between a drug taken orally and the actual amount of a drug reaching the circulatory system, oral bioavailability is an essential parameter for determining the efficacy and adverse effects of new and developing medications, as well as finding an optimal dosing regimen. This book provides a much-needed one-stop resource to help readers better understand and appreciate the many facets and complex problems of oral bioavailability, including the basic barriers to oral bioavailability, the methods used to determine relevant parameters, and the challenges of drug delivery. In addition, this comprehensive book discusses biological and physicochemical methods for improving bioavailability, integrates physicochemistry with physiology and molecular biology, and includes several state-of-the-art technologies and approaches Caco-2 cell culture model, MDCK, and other related cell culture models which are used to study the science of oral bioavailability.
Oral Bioavailability and Drug Delivery
Author: Ming Hu
Publisher: John Wiley & Sons
ISBN: 1119660688
Category : Medical
Languages : en
Pages : 932
Book Description
ORAL BIOAVAILABILITY AND DRUG DELIVERY Improve the performance and viability of newly-developed and approved drugs with this crucial guide Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development. Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research. Oral Bioavailability and Drug Delivery readers will also find: Discussion questions in many chapters to facilitate comprehension Detailed discussion of topics including dissolution, absorption, metabolism, and more Real-world examples of methods in actions throughout Oral Bioavailability and Drug Delivery is ideal for pharmaceutical and biotechnology scientists working in drug discovery and development; researchers in chemistry, biology, pharmacology, immunology, neuroscience, and other related fields; and graduate courses in drug development and delivery.
Publisher: John Wiley & Sons
ISBN: 1119660688
Category : Medical
Languages : en
Pages : 932
Book Description
ORAL BIOAVAILABILITY AND DRUG DELIVERY Improve the performance and viability of newly-developed and approved drugs with this crucial guide Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development. Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research. Oral Bioavailability and Drug Delivery readers will also find: Discussion questions in many chapters to facilitate comprehension Detailed discussion of topics including dissolution, absorption, metabolism, and more Real-world examples of methods in actions throughout Oral Bioavailability and Drug Delivery is ideal for pharmaceutical and biotechnology scientists working in drug discovery and development; researchers in chemistry, biology, pharmacology, immunology, neuroscience, and other related fields; and graduate courses in drug development and delivery.
The use of large animal models to improve pre-clinical translational research
Author: Mark Gray
Publisher: Frontiers Media SA
ISBN: 2832519326
Category : Medical
Languages : en
Pages : 161
Book Description
Publisher: Frontiers Media SA
ISBN: 2832519326
Category : Medical
Languages : en
Pages : 161
Book Description
Hypoxia and Cardiorespiratory Control
Author: Yasumasa Okada
Publisher: Frontiers Media SA
ISBN: 2889743136
Category : Science
Languages : en
Pages : 170
Book Description
Publisher: Frontiers Media SA
ISBN: 2889743136
Category : Science
Languages : en
Pages : 170
Book Description
Drug Discovery and Evaluation: Pharmacological Assays
Author: Hans Vogel
Publisher: Springer Science & Business Media
ISBN: 3540714200
Category : Medical
Languages : en
Pages : 2118
Book Description
The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.
Publisher: Springer Science & Business Media
ISBN: 3540714200
Category : Medical
Languages : en
Pages : 2118
Book Description
The new edition of this successful reference offers both cutting-edge and classic pharmacological methods. Thoroughly revised and expanded to two volumes, it offers an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Every chapter has been updated, and numerous assays have been added. Each of the more than 1,000 assays comprises a detailed protocol outlining purpose and rationale, and a critical assessment of the results and their pharmacological and clinical relevance.
Cumulated Index Medicus
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1292
Book Description
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1292
Book Description