Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants PDF Download
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Author: Yvonne Will
Publisher: John Wiley & Sons
ISBN: 1119329736
Category : Science
Languages : en
Pages : 813
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Book Description
Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. • Covers both basic science and applied technology / methods • Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects • Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development • Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
Author: Yvonne Will
Publisher: John Wiley & Sons
ISBN: 1119329736
Category : Science
Languages : en
Pages : 813
Get Book Here
Book Description
Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. • Covers both basic science and applied technology / methods • Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects • Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development • Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
Author:
Publisher:
ISBN:
Category : Psychopharmacology
Languages : en
Pages : 1144
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Book Description
Author:
Publisher:
ISBN:
Category : Alcoholism
Languages : en
Pages : 480
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Book Description
Author: Alessandra Stasi
Publisher: Frontiers Media SA
ISBN: 2832519857
Category : Medical
Languages : en
Pages : 153
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Book Description
Author: Kjell Heuser
Publisher: Frontiers Media SA
ISBN: 2889713164
Category : Medical
Languages : en
Pages : 226
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Book Description
Author: Mark A. Suckow
Publisher: Academic Press
ISBN: 0128143398
Category : Science
Languages : en
Pages : 1182
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Book Description
The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research. - New chapters on the care of surgical and fragile models and on the use of rats in research areas such as alcoholism, regenerative medicine, spinal cord injury, traumatic brain injury, and others are included. - All chapters were written by scientific and veterinary experts. - This book condenses information from many sources on topics related to the care and use of rats in research. - It is the premier source of information on the laboratory rat.
Author: Robert H. Weichbrod
Publisher: CRC Press
ISBN: 1498748457
Category : Medical
Languages : en
Pages : 917
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Book Description
AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).
Author: Roger Walsh
Publisher: Springer Science & Business Media
ISBN: 1468430815
Category : Medical
Languages : en
Pages : 383
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Book Description
At the 1975 Winter Conference on Brain Research a series of workshops were held to discuss the role of the sensory environment in the etiology and therapy of brain dysfunction. The participants represented a broad range of disciplines ranging from basic neuro science through human development psychology. They were linked by a common belief that the role of the sensory environment in brain dysfunction had received insufficient attention. Each had made contributions to this question in their own respective disciplines and it was hoped that this meeting would provide an opportunity for cross fertilization and synthesis. From these workshops this book evolved. Its production would have been impossible without the help of many people. Anna Taylor's flexibility allowed the holding of a larger than normal workshop, while the authors bore up well under editorial pressure to meet deadlines. Linda Coleman and Phyllis Straw provided excellent support from Plenum while Therese Linden gave editorial assistance. Valarie Munden, Rosemary Schmele, and Estelle Hoffman did an excellent job of typing. RNW was supported by a Fellowship from the Foundations' Fund for Research in Psychiatry. As always, our families provided continuous support and encouragement. To all these people and more we say thank you. Roger N. Walsh M.D., B.Med.Sc., Dip.Psychol., Ph.D. William T. Greenough, Ph.D.
Author: Alan Leek
Publisher:
ISBN: 9780369375346
Category :
Languages : en
Pages : 0
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Book Description
Author: David B. Teplow
Publisher: Academic Press
ISBN: 0123858836
Category : Medical
Languages : en
Pages : 499
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Book Description
Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson's, Alzheimer's and Huntington's disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases. This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases. Contributions from leading authorities Informs and updates on all the latest developments in the field
