Radiotherapy for Non-Malignant Disorders

Radiotherapy for Non-Malignant Disorders PDF Author: Michael Heinrich Seegenschmiedt
Publisher: Springer Science & Business Media
ISBN: 3540689435
Category : Medical
Languages : en
Pages : 729

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Book Description
This volume discusses the background and various clinical applications of radiation therapy in the treatment of non-malignant diseases. It documents the radiobiological and physical principles of treatment and the rationale underlying the use of radiotherapy for various disorders of the CNS, head and neck, eye, skin and soft tissues, bone and joints, and vascular system. In so doing, it draws attention to and elucidates the scope for application of radiotherapy beyond the treatment of malignancies. Both the risks and the benefits of such treatment are fully considered, the former ranging from minor clinical problems to life-threatening diseases.

Radiotherapy for Non-Malignant Disorders

Radiotherapy for Non-Malignant Disorders PDF Author: Michael Heinrich Seegenschmiedt
Publisher: Springer Science & Business Media
ISBN: 3540689435
Category : Medical
Languages : en
Pages : 729

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Book Description
This volume discusses the background and various clinical applications of radiation therapy in the treatment of non-malignant diseases. It documents the radiobiological and physical principles of treatment and the rationale underlying the use of radiotherapy for various disorders of the CNS, head and neck, eye, skin and soft tissues, bone and joints, and vascular system. In so doing, it draws attention to and elucidates the scope for application of radiotherapy beyond the treatment of malignancies. Both the risks and the benefits of such treatment are fully considered, the former ranging from minor clinical problems to life-threatening diseases.

Radiation Treatment and Radiation Reactions in Dermatology

Radiation Treatment and Radiation Reactions in Dermatology PDF Author: Renato G. Panizzon
Publisher: Springer
ISBN: 9783662448250
Category : Medical
Languages : en
Pages : 193

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Book Description
In this book, leading experts in the dermatological and oncological field describe the use of radiation therapy for the treatment of the full range of dermatological malignancies – including basal cell carcinoma, squamous cell carcinoma, cutaneous lymphomas, Kaposi's sarcoma, melanoma, and Merkel cell tumor – as well as those precancerous lesions and non-malignant dermatological disorders which are amenable to radiation therapy. In each case the specific indications for the use of radiotherapy and its application are clearly explained with the aid of numerous high-quality illustrations. In addition, the book provides a concise introduction to physical and radiobiological principles, selection of radiation factors, dose definitions, radiation reactions, and risk assessments. The new edition has been thoroughly revised and updated to reflect advances in practical knowledge and clinical practice. It will be an invaluable source of information on the management of skin tumors and related non-malignant disorders for both dermatologists, oncologists and radiation oncologists.

Evolving Role of PET in Assessing the Efficacy of Immunotherapy and Radiation Therapy in Malignant Disorders,An Issue of PET Clinics E-Book

Evolving Role of PET in Assessing the Efficacy of Immunotherapy and Radiation Therapy in Malignant Disorders,An Issue of PET Clinics E-Book PDF Author: Abass Alavi
Publisher: Elsevier Health Sciences
ISBN: 0323710735
Category : Medical
Languages : en
Pages : 145

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Book Description
This issue of PET Clinics focuses on Evolving Role of PET in Assessing the Efficacy of Immunotherapy and Radiation Therapy in Malignant Disorders, and is edited by Drs. Charles B. Simone II, Nicolas Aide, and Abass Alavi (the Consulting Editor of PET Clinics). Articles will include: The Value of PET Imaging to Guide Target Delineation for Radiation Oncology; PET Imaging to Determine Radiation Dose, Adapt Radiation Plans, and Predict Patterns of Failure and Overall Survival for Non-small Cell Lung Cancer; The Utility of PET/CT for Radiation Oncology Planning, Surveillance, and Prognosis Prediction for Gastrointestinal Tumors; Evolving Role of PET Based Novel Quantitative Techniques to Detect Radiation-induced Complications; Current and Future PET Based Quantitative techniques to Assess Response to Radiation Therapy; Diagnosis, Staging, Radiation Treatment Response Assessment, and Prognostication; FDG PET/CT for Assessing Tumour Response to Immunotherapy and Detecting Immune-related Side Effects: A Checklist for the PET Reader; PET Imaging with Therapeutic Antibody-based PD-1/PD-L1 Checkpoint Tracers; FDG PET/CT for Assessing Tumour Response to Immunotherapy in Lymphomas; FDG PET/CT for Assessing Tumour Response to Immunotherapy in Solid Tumours: Melanoma and Beyond; and more!

The Radiotherapy of Malignant Disease

The Radiotherapy of Malignant Disease PDF Author: R.C.S. Pointon
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 504

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Book Description
Radiotherapy as practiced at the renowned Christie Hospital and Holt Radium Institute is brought up to date in this new, second edition of The Radiotherapy of Malignant Disease. The contributions are all written by current or former members of the hospital staff. The opening chapters provide the necessary background information: basic physics and radiobiology, principles of chemotherapy, and mould room practice. The main part of the book represents the very essence of the Manchester school of thought. It is designed to show in detail how to treat, by X-rays and radium, malignant tumors in various anatomical sites. The book thus gives practical guidance on clinical techniques necessary in all disciplines involved in the management of malignant disease. From the reviews of the first edition: " ...It should be in the library of every radiotherapy department, and in the hands of every trainee..." #British Medical Journal#1 "...This book should be an important and interesting reference book on the shelves of any medical library or radiotherapist's office." #American Journal of Roentgenology#2 "...There can...be few established radiotherapists, described by the editors as the epitome of the oncologist, who did not read the earlier versions of the Manchester textbook and may still use it for reference. This latest edition is costly but it should continue to be read by all trainees aspiring to the DMRT and FRCR, wherever they may be in training and whatever the philosophy of their teachers." #Journal of the Royal Society of Medicine#3

Radiation Therapy of Benign Diseases

Radiation Therapy of Benign Diseases PDF Author: Stanley E. Order
Publisher: Springer Science & Business Media
ISBN: 3642971601
Category : Medical
Languages : en
Pages : 365

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Book Description
The radiation therapist's primary concern is the treatment of patients with malignant dis ease. However, there are definite indications for radiation treatment for benign diseases that do not respond to conventional methods of treatment. It may be the treatment of choice in the unusual instance of a life-threatening benign disease that cannot be surgi cally or medically managed. The present volume by Order and Donaldson represents a major statement on the uti lization of radiation techniques in the management of benign disease. The initial report of the Committee on Radiation Treatment of Benign Disease from the Bureau of Radiological Health recommended that consideration be given to the quality of radiation, the total dose, overall time, underlying organs at risk and shielding factors before the institution of radiation therapy. Infants and children should be treated with ionizing radiation only in very exceptional cases and after careful evaluation of the potential risk compared with the expected benefit. Direct irradiation of the skin areas overlying organs that are particularly prone to late effects such as the thyroid, eye, go nads, bone marrow, and breast should be avoided. Meticulous radiation protection tech niques should be used in all instances and the depth of penetration of the x-ray beam should be chosen in accordance with depth of the pathologic process'.

The European Blood and Marrow Transplantation Textbook for Nurses

The European Blood and Marrow Transplantation Textbook for Nurses PDF Author: Michelle Kenyon
Publisher: Springer
ISBN: 3319500260
Category : Medical
Languages : en
Pages : 311

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Book Description
This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Stereotactic Body Radiation Therapy

Stereotactic Body Radiation Therapy PDF Author: Simon S. Lo
Publisher: Springer Science & Business Media
ISBN: 364225604X
Category : Medical
Languages : en
Pages : 433

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Book Description
Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Radiation and the Immune System: Current Knowledge and Future Perspectives

Radiation and the Immune System: Current Knowledge and Future Perspectives PDF Author: Katalin Lumniczky
Publisher: Frontiers Media SA
ISBN: 2889454746
Category :
Languages : en
Pages : 283

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Book Description
For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.

Modern Dermatologic Radiation Therapy

Modern Dermatologic Radiation Therapy PDF Author: Herbert Goldschmidt
Publisher: Springer Science & Business Media
ISBN: 1461390419
Category : Medical
Languages : en
Pages : 166

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Book Description
Radiation therapy of cutaneous cancers and other dermatologic disorders is not covered adequately in many current textbooks of dermatology and radiation oncology. This book is intended to fill that gap. Both text and illustrations are oriented toward the practical aspects of radiation therapy. The beginner will find a concise introduction to physical and biological principles, selec tion of radiation factors, dose definitions, indications for treatment, and radiation seque lae. The experienced dermatologist and radiation oncologist will find a detailed discussion of specific indications for various radiation techniques in different body regions. A special effort was made to add pertinent references to the world literature for those who wish to pursue particular topics still further. We have tried to include all major American and European publications of the last 20 years in our bibliography of more than 500 refer ences, and we also have attempted to review the most important scientific papers on prin ciples and practice of ionizing radiation therapy in a constructive way. We are grateful to Professor Gorson, Dr. Breneman, and Professor Lindel6f, who generously contributed chapters in their areas of expertise despite their many other com mitments.

Health Risks from Exposure to Low Levels of Ionizing Radiation

Health Risks from Exposure to Low Levels of Ionizing Radiation PDF Author: Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher: National Academies Press
ISBN: 0309133343
Category : Science
Languages : en
Pages : 422

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Book Description
This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.