Quantification of Somatic Synapse Formation in the Supraoptic Nucleus of Adult Rats Following Chronic Dehydration PDF Download
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Author: Barbara Kay Modney
Publisher:
ISBN:
Category : Dehydration (Physiology)
Languages : en
Pages : 158
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Book Description
Author: Barbara Kay Modney
Publisher:
ISBN:
Category : Dehydration (Physiology)
Languages : en
Pages : 158
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Book Description
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 1170
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Book Description
Author: Hubert Vaudry
Publisher: Springer Science & Business Media
ISBN: 9781402073069
Category : Medical
Languages : en
Pages : 432
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Book Description
Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.
Author: Jian-Sheng Lin
Publisher: Frontiers Media SA
ISBN: 2889194345
Category : Brain
Languages : en
Pages : 100
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Book Description
Brain aminergic pathways are organized in parallel and interacting systems, which support a range of functions, from homoeostatic regulations to cognitive, and motivational processes. Despite overlapping functional influences, dopamine, serotonin, noradrenaline and histamine systems provide different contributions to these processes. The histaminergic system, long ignored as a major regulator of the sleep-wake cycle, has now been fully acknowledged also as a major coordinator of attention, learning and memory, decision making. Although histaminergic neurons project widely to the whole brain, they are functionally heterogeneous, a feature which may provide the substrate for differential regulation, in a region-specific manner, of other neurotransmitter systems. Neurochemical preclinical studies have clearly shown that histamine interacts and modulates the release of neurotransmitters that are recognized as major modulators of cognitive processing and motivated behaviours. As a consequence, the histamine system has been proposed as a therapeutic target to treat sleep-wake disorders and cognitive dysfunctions that accompany neurodegenerative and neuroinflammatory pathologies. Last decades have witnessed an unexpected explosion of interest in brain histamine system, as new receptors have been discovered and selective ligands synthesised. Nevertheless, the complete picture of the histamine systems fine-tuning and its orchestration with other pathways remains rather elusive. This Research Topic is intended to offer an inter-disciplinary forum that will improve our current understanding of the role of brain histamine and provide the fundamentals necessary to drive innovation in clinical practice and to improve the management and treatment of neurological disorders.
Author: Chikako Tanaka
Publisher: Springer Science & Business Media
ISBN: 9783764352844
Category : Medical
Languages : en
Pages : 354
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Book Description
Highlighting the current developments and future directions in GABA research, the ambitious aim of this topical volume is to cover GABA from the molecular mechanisms of its transmission to new targets for pharmaceutical research. Distinguished scientists at the forefront of GABA research were invited to contribute reviews on glutamate decarboxylase and autoimmunity, molecular structure and functional regulation of GABA transporters, transmitter release and GABA receptor regulation, GABA receptor subtypes and functional regulation, and GABA receptor ligands and their therapeutic application. Describing the latest advances in what has become a rapidly-evolving field, this volume will prove immensely valuable to neuroscientists, pharmacologists, biochemists, and physiologists working in the field of GABA research.
Author: Guillaume Lebon
Publisher: Springer
ISBN: 3030245918
Category : Science
Languages : en
Pages : 299
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Book Description
This book introduces readers to the latest advances in G protein-coupled receptor (GPCR) biology. It reviews our current understanding of the structural basis of ligand binding and allosteric mechanisms, following a decade of technological breakthroughs. Several examples of structure-based drug discovery are presented, together with the future challenges involved in designing better drugs that target GPCRs. In turn, the book illustrates the important concept of GPCR biased signaling in physiological contexts, and presents fluorescent- and light-based methodologies frequently used to measure GPCR signaling or to trace their dynamics in cells upon ligand activation. Taken together, the chapters provide an essential overview and toolkit for new scientific investigators who plan to develop GPCR projects. All chapters were written by experts in their respective fields, and share valuable insights and powerful methodologies for the GPCR field.
Author: Paul D. Sturkie
Publisher: Springer Science & Business Media
ISBN: 1461248620
Category : Science
Languages : en
Pages : 528
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Book Description
Since the publication of earlier editions, there has been The new edition has a number of new contributors, a considerable increase in research activity ina number who have written on the nervous system, sense organs, of areas, with each succeeding edition including new muscle, endocrines, reproduction, digestion and immu chapters and an expansion of knowledge in older chap nophysiology. Contributors from previous editions ters. have expanded their offerings considerably. The fourth edition contains two new chapters, on The authors are indebted to various investigators, muscle and immunophysiology, the latter an area journals and books for the many illustrations used. Indi where research on Aves has contributed significantly vidual acknowledgement is made in the legends and to our general knowledge of the subject. references. Preface to the 'Third Edition Since the publication of the first and second editions, pathways of birds and mammals. New contributors in there has been a considerable increase of research activ clude M. R. Fedde and T. B. Bolton, who have com ity in avian physiology in a number of areas, including pletely revised and expanded the chapters on respira endocrinology and reproduction, heart and circulation, tion and the nervous system, respectively, and J. G. respiration, temperature regulation, and to a lesser ex Rogers, Jr. , W. J. Mueller, H. Opel, and D. e. Meyer, who have made contributions to Chapters 2,16, 17, tent in some other areas. There appeared in 1972-1974 a four volume treatise and 19, respectively.
Author: Daniel Pedro Cardinali
Publisher: Springer
ISBN: 3319575716
Category : Medical
Languages : en
Pages : 393
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Book Description
A traditional view of the Autonomic Nervous System (ANS) considers only its peripheral part: the sympathetic and parasympathetic systems. However, this view misses to consider the most important ANS function: the maintenance of homeostasis. This term is used today to define not only the strategies that allow the body proper response to changes in the environment (reactive homeostasis), but also temporal mechanisms that allow the body to predict the most likely timing of environmental stimuli (predictive homeostasis based on biological rhythms). This book discusses the ANS from both an enlarged and a timed perspective. First, it presents how the organization of the ANS is hierarchical into different levels. Following that, the book discusses how the ANS changes functionally in the three-body configurations (wakefulness, slow sleep, rapid eye movement sleep) found in a 24-hour cycle. Finally, the most important clinical implications of this enlarged and timed vision of ANS will be discussed. Autonomic Nervous System – Basic and Clinical Aspects is a comprehensive text intended for medical students and health professionals who are interested in a deeper approach to this important part of the nervous system. It provides a detailed and complete understanding of the neuroscience behind the ANS, allowing a proper clinical applicability of this knowledge.
Author: Qi Wu
Publisher: Springer
ISBN: 9811312869
Category : Medical
Languages : en
Pages : 240
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Book Description
This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.
Author: Kinji Yagi
Publisher: John Wiley & Sons
ISBN:
Category : Medical
Languages : en
Pages : 422
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Book Description
