Qualitative and Quantitative Analysis of Bioactive Natural Products 2018

Qualitative and Quantitative Analysis of Bioactive Natural Products 2018 PDF Author: Maria Carla Marcotullio
Publisher: MDPI
ISBN: 3038977888
Category : Science
Languages : en
Pages : 374

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Book Description
Throughout most of history, medicinal plants and their active metabolites have represented a valuable source of compounds used to prevent and to cure several diseases. Interest in natural compounds is still high as they represent a source of novel biologically/pharmacologically active compounds. Due to their high structural diversity and complexity, they are interesting structural scaffolds that can offer promising candidates for the study of new drugs, functional foods, and food additives. Plant extracts are a highly complex mixture of compounds and qualitative and quantitative analyses are necessary to ensure their quality. Furthermore, greener methods of extraction and analysis are needed today. This book is based on articles submitted for publication in the Special Issue entitled “Qualitative and Quantitative Analysis of Bioactive Natural Products” that collected original research and reviews on these topics.

Qualitative and Quantitative Analysis of Bioactive Natural Products 2018

Qualitative and Quantitative Analysis of Bioactive Natural Products 2018 PDF Author: Maria Carla Marcotullio
Publisher: MDPI
ISBN: 3038977888
Category : Science
Languages : en
Pages : 374

Get Book Here

Book Description
Throughout most of history, medicinal plants and their active metabolites have represented a valuable source of compounds used to prevent and to cure several diseases. Interest in natural compounds is still high as they represent a source of novel biologically/pharmacologically active compounds. Due to their high structural diversity and complexity, they are interesting structural scaffolds that can offer promising candidates for the study of new drugs, functional foods, and food additives. Plant extracts are a highly complex mixture of compounds and qualitative and quantitative analyses are necessary to ensure their quality. Furthermore, greener methods of extraction and analysis are needed today. This book is based on articles submitted for publication in the Special Issue entitled “Qualitative and Quantitative Analysis of Bioactive Natural Products” that collected original research and reviews on these topics.

Bioactive natural products-oriented synthetic and functional studies

Bioactive natural products-oriented synthetic and functional studies PDF Author: Shao-Hua Wang
Publisher: Frontiers Media SA
ISBN: 2832526853
Category : Science
Languages : en
Pages : 240

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Book Description


Advances in Chemical Analysis Procedures (Part I)

Advances in Chemical Analysis Procedures (Part I) PDF Author: Marcello Locatelli
Publisher: MDPI
ISBN: 3039365770
Category : Medical
Languages : en
Pages : 162

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Book Description
The availability (and the development) of innovative approaches to quantitative analyses and the data processing are often mandatory to deeply characterize a sample and to correctly highlight the analytical target. These objectives are carried out either by simply improving a single aspect of the analytical protocol or by developing a synergy of steps (from extraction to instrumental configuration to chemometric approaches) to obtain the maximum analytical information sought. Examples are innovative extraction protocols (also following the recent guidelines on green analytical chemistry) or new materials for the selective extraction of target compounds, multi-analytes screening methods, and "untargeted" approaches for food applications. In this text, the various articles are attributable to these elements, in particular, we start with a multi-analyte method for the determination of 10 different cannabinoids from Cannabis sativa L. by means of conventional techniques (Mandrioli and coworkers), to then see the application of techniques hyphenated "ultra-fast" by UPLC-MS for the authentication of food products (Xue and coworkers). The work of Song and coworkers on these applications in food products is also interesting, as it highlights how the collection process (and the timing of this passage) can affect the chemical profile and, consequently, the biological activity of Panax ginseng. Mocan and coworkers, applying an innovative extraction technique based on microwaves and applying well-known, robust, and easy-to-use instrumentation, have demonstrated how it is possible to discriminate between various species of Galium and how the chemical profiles obtained can support the biological activities observed. Similarly, but with the aim of developing new sample pretreatment procedures, Maggira and collaborators have developed graphene oxide-based materials for the selective extraction of sulfonamides in milk. Shen and coworkers apply a different type of approach, the "untargeted" one, for the geographical characterization of the Gentian Rigescens for which they combine chemometric techniques for the processing of raw chemical profile data. Wang and coworkers report a multiclass screening of drugs with high-resolution mass spectrometry through which they manage to obtain a high-scale, fast screening method for pesticides in fishery drugs based on ultrahigh-performance liquid chromatography tandem quadrupole-orbitrap high-resolution mass spectrometer.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry PDF Author: Atta-ur Rahman
Publisher: Elsevier
ISBN: 0323989241
Category : Science
Languages : en
Pages : 440

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Book Description
Studies in Natural Products Chemistry, Volume 70 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, this book presents exciting opportunities in the field of new drug development to the pharmaceutical industry. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores

The discovery of bioactive natural products: The isolation and structural elucidation, genome mining, OSMAC strategy, and biotransformation

The discovery of bioactive natural products: The isolation and structural elucidation, genome mining, OSMAC strategy, and biotransformation PDF Author: Ling Liu
Publisher: Frontiers Media SA
ISBN: 2832532756
Category : Science
Languages : en
Pages : 161

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Book Description


Recent Advances in Natural Products Analysis

Recent Advances in Natural Products Analysis PDF Author: Seyed Mohammad Nabavi
Publisher: Elsevier
ISBN: 0128164557
Category : Science
Languages : en
Pages : 878

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Book Description
Recent Advances in Natural Products Analysis is a thorough guide to the latest analytical methods used for identifying and studying bioactive phytochemicals and other natural products. Chemical compounds, such as flavonoids, alkaloids, carotenoids and saponins are examined, highlighting the many techniques for studying their properties. Each chapter is devoted to a compound category, beginning with the underlying chemical properties of the main components followed by techniques of extraction, purification and fractionation, and then techniques of identification and quantification. Biological activities, possible interactions, levels found in plants, the effects of processing, and current and potential industrial applications are also included.

Bioactive Natural Products for Pharmaceutical Applications

Bioactive Natural Products for Pharmaceutical Applications PDF Author: Dilipkumar Pal
Publisher: Springer Nature
ISBN: 3030540278
Category : Technology & Engineering
Languages : en
Pages : 872

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Book Description
This book covers the recent innovations relating to various bioactive natural products (such as alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, volatile oils, fixed oils, fats and waxes, proteins and peptides, vitamins, marine products, camptothecin, piperines, carvacrol, gedunin, GABA, ginsenosides) and their applications in the pharmaceutical fields related to academic, research and industry.

Natural Products as Source of Molecules with Therapeutic Potential

Natural Products as Source of Molecules with Therapeutic Potential PDF Author: Valdir Cechinel Filho
Publisher: Springer
ISBN: 3030005453
Category : Science
Languages : en
Pages : 531

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Book Description
This book addresses the highly relevant and complex subject of research on drugs from natural products, discussing the current hot topics in the field. It also provides a detailed overview of the strategies used to research and develop these drugs. Respected experts explore issues involved in the production chain and when looking for new medicinal agents, including aspects such as therapeutic potential, functional foods, ethnopharmacology, metabolomics, virtual screening and regulatory scenarios. Further, the book describes strategic methods of isolation and characterization of active principles, biological assays, biotechnology of plants, synthesis, clinical trials and the use of tools to identity active principles.

Understanding and optimising the nutraceutical properties of fruit and vegetables

Understanding and optimising the nutraceutical properties of fruit and vegetables PDF Author: Professor Victor R. Preedy
Publisher: Burleigh Dodds Science Publishing
ISBN: 1786768526
Category : Science
Languages : en
Pages : 347

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Book Description
Provides a comprehensive overview of the wealth of research on analysing, understanding and optimising the nutraceutical properties of fruit and vegetables, focussing primarily on phytochemicals/phytochemical compounds Reviews the current research on mechanisms of action and the potential role of key phytochemical compounds, such as antioxidants and flavonoids, in preventing the onset of chronic diseases Explores current advances in understanding and improving the nutraceutical properties of key horticultural crops, including apples, cranberries, broccoli and other brassicas

Natural Products Analysis

Natural Products Analysis PDF Author: Vladimir Havlicek
Publisher: John Wiley & Sons
ISBN: 1118466616
Category : Science
Languages : en
Pages : 634

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Book Description
This book highlights analytical chemistry instrumentation and practices applied to the analysis of natural products and their complex mixtures, describing techniques for isolating and characterizing natural products. • Applies analytical techniques to natural products research – an area of critical importance to drug discovery • Offers a one-stop shop for most analytical methods: x-ray diffraction, NMR analysis, mass spectrometry, and chemical genetics • Includes coverage of natural products basics and highlights antibacterial research, particularly important as efforts to combat drug resistance gain prominence • Covers instrumental techniques with enough detail for both current practitioners and beginning researchers