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Author: Mitchell D. Cohen
Publisher: Springer Science & Business Media
ISBN: 1461545358
Category : Medical
Languages : en
Pages : 492
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Book Description
Pulmonary Immunotoxicology is a comprehensive exploration of the effects of various inhaled materials upon the immune system of the respiratory tract. It will be useful to investigators in the field of pulmonary toxicology and immunotoxicology, and to those involved in administration and regulation of matters related to inhaled materials. It can also serve as a textbook for a course in pulmonary immunotoxicology at graduate or advanced undergraduate level. Pulmonary Immunotoxicology comprises four sections. The first provides basic background concepts essential for understanding pulmonary immunotoxicology, including discussions of the normal structure and function of the respiratory system, its basic immunology, and the manner by which inhaled particles and gases are removed from the air and deposited upon respiratory tract surfaces. The second section provides an overview of the major types of pathological consequences which can arise from immunomodulation within the respiratory tract, including hypersensitivity and asthma, inflammation and fibrosis, as well as immunosuppression and autoimmunity. The third section, which comprises the largest portion of the book, deals specifically with major classes of airborne agents that are known to alter the immune function of the respiratory tract. These are arranged into major classes: organic agents, metals, gases, particles, biologics, and complex mixtures. The fourth and final section of the book explores the area of risk assessment, including discussions of the basic concepts of risk assessment as they apply specifically to immunotoxicologic effects upon the lungs, and the use of biomarkers as indices of potential pulmonary immunotoxic responses to inhaled materials.
Author: Mitchell D. Cohen
Publisher: Springer Science & Business Media
ISBN: 1461545358
Category : Medical
Languages : en
Pages : 492
Get Book Here
Book Description
Pulmonary Immunotoxicology is a comprehensive exploration of the effects of various inhaled materials upon the immune system of the respiratory tract. It will be useful to investigators in the field of pulmonary toxicology and immunotoxicology, and to those involved in administration and regulation of matters related to inhaled materials. It can also serve as a textbook for a course in pulmonary immunotoxicology at graduate or advanced undergraduate level. Pulmonary Immunotoxicology comprises four sections. The first provides basic background concepts essential for understanding pulmonary immunotoxicology, including discussions of the normal structure and function of the respiratory system, its basic immunology, and the manner by which inhaled particles and gases are removed from the air and deposited upon respiratory tract surfaces. The second section provides an overview of the major types of pathological consequences which can arise from immunomodulation within the respiratory tract, including hypersensitivity and asthma, inflammation and fibrosis, as well as immunosuppression and autoimmunity. The third section, which comprises the largest portion of the book, deals specifically with major classes of airborne agents that are known to alter the immune function of the respiratory tract. These are arranged into major classes: organic agents, metals, gases, particles, biologics, and complex mixtures. The fourth and final section of the book explores the area of risk assessment, including discussions of the basic concepts of risk assessment as they apply specifically to immunotoxicologic effects upon the lungs, and the use of biomarkers as indices of potential pulmonary immunotoxic responses to inhaled materials.
Author: David S Newcombe
Publisher: CRC Press
ISBN: 9781439805411
Category : Medical
Languages : en
Pages : 470
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Book Description
This text is a comprehensive source of information on the toxic effects of environmental, industrial, and pharmacological agents on the human immune system. Focusing entirely on human immunotoxicology, without relying on animal models, the book explains the basic principles of immunotoxicology defines the mechanisms by which immunotoxins act, describes the clinical expression of immunotoxic disorders in the lung, skin, and other target organs, offers practical guidelines for early detection and control of host defense dysfunctions, and explores strategies for assessing the short- and long-term health effects of new and old chemicals and biologicals. The book includes extensive discussions on the role of low-dose, chronic immunosuppression in cancer, as well as on specific environmental and occupational immunotoxins and immunotoxic drugs used in hematology, anesthesiology, oncology and transplantation surgery.
Author: National Research Council
Publisher: National Academies Press
ISBN: 9780309039901
Category : Science
Languages : en
Pages : 204
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Book Description
Biologic markersâ€"indicators of biological exposure or changeâ€"offer the promise of early detection of disease caused by environmental exposure. Researchers have used these markers to discover indications of pulmonary damage from low-level ozone, a finding with serious implications for health professionals and environmental regulators. Biologic Markers in Pulmonary Toxicology is a comprehensive study of this use of biologic markers. Focusing on the respiratory tract as an entryway for airborne pollutants, this volume reviews new ways of measuring markers, the need for markers to indicate dose or exposure levels, noninvasive respiratory function tests for use with healthy humans to detect sensitivity to inhaled pollutants, approaches to evaluating markers down to the cellular and biochemical levels, and more.
Author: Ralph J. Smialowicz
Publisher: CRC Press
ISBN:
Category : Business & Economics
Languages : en
Pages : 518
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Book Description
Immunotoxicology has emerged as a vital and expanding discipline over the past several years. Although the field of human immunotoxicology is arguably still in its infancy, a number of animal model systems have been well established and validated. Experimental Immunotoxicology provides an update on the recent advances in the field as it relates to animals and provokes discussion on approaches to the evaluation of human immunotoxicology. It is an important reference source for professionals in immunology and toxicology. The book begins with an overview of the mammalian immune system and covers the important role played by animal host susceptibility models. It also gives an update on immunotoxicolgy in sub-human primates. Vulnerability of bone marrow and the consequences of damage to immune function as well as chemical-induced immunosuppression as a consequence of exposure to chemicals are covered. Most of the chapters are organized to include a description of the profile of immunotoxicity, mechanisms of immunotoxicity, species comparisons and research needs.
Author: Mitchell D. Cohen
Publisher: Springer Science & Business Media
ISBN: 9780792378433
Category : Medical
Languages : en
Pages : 492
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Book Description
A reference for investigators in pulmonary toxicology and immunotoxicology and for people involved in administrating and regulating matters related to inhale materials, and serviceable as a textbook for a graduate or advanced undergraduate course in pulmonary immunotoxicology. US researchers from academic and industrial laboratories provide information concerning the effects of various inhaled materials on the immune system of the respiratory tract. They cover basic background concepts including the normal structure and function of the respiratory system and its basic immunology, the major types of pathological consequences that can arise from immunomodulation within the respiratory tract, the specific major classes of airborne agents that are known to alter immune function, and risk assessment. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Jack H. Dean
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 540
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Book Description
Author: Gary R. Burleson
Publisher:
ISBN: 9780471561972
Category : Immune system
Languages : en
Pages : 504
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Book Description
Author:
Publisher:
ISBN:
Category : Beryllium
Languages : en
Pages : 298
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Book Description
Author: Charlene A. McQueen
Publisher: Pergamon
ISBN: 9780080423012
Category : Science
Languages : en
Pages : 564
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Book Description
Comprehensive Toxicology - the first comprehensive reference work in toxicology, is an in-depth, state-of-the-art review of toxicology of unrivalled quality. It is designed to encompass investigation from a molecular level to the intact organism. Presented in a 13-volume printed form.
Author: Peterson's Guides Staff
Publisher: Peterson Nelnet Company
ISBN: 9780768924060
Category : Education
Languages : en
Pages : 1642
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Book Description
The six volumes of Peterson's Annual Guides to Graduate Study, the only annually updated reference work of its kind, provide wide-ranging information on the graduate and professional programs offered by accredited colleges and universities in the United States and U.S. territories and those in Canada, Mexico, Europe, and Africa that are accredited by U.S. accrediting bodies. Books 2 through 6 are divided into sections that contain one or more directories devoted to individual programs in a particular field. Book 3 contains more than 4,000 programs of study in 53 disciplines of the biological sciences.
