Protein Toxins in Modeling Biochemistry PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Protein Toxins in Modeling Biochemistry PDF full book. Access full book title Protein Toxins in Modeling Biochemistry by Raj Kumar. Download full books in PDF and EPUB format.
Author: Raj Kumar
Publisher: Springer
ISBN: 331943540X
Category : Science
Languages : en
Pages : 163
Get Book Here
Book Description
This succinct volume addresses the production of inactive, potentially toxic proteins in the absence of correct protein folding and the resultant neurodegenerative diseases. Other topics include intrinsic disorder in protein structure and function and the effects of molten globules on protein toxicity. This concise and yet thorough text also discusses using toxin structure as a model for studying structural and functional aspects of protein chemistry. Protein Toxins in Modeling Biochemistry, a SpringerBrief, is essential reading for advanced researchers, scientists and advanced graduate students interested in protein chemistry and related areas of biochemistry and molecular science.
Author: Raj Kumar
Publisher: Springer
ISBN: 331943540X
Category : Science
Languages : en
Pages : 163
Get Book Here
Book Description
This succinct volume addresses the production of inactive, potentially toxic proteins in the absence of correct protein folding and the resultant neurodegenerative diseases. Other topics include intrinsic disorder in protein structure and function and the effects of molten globules on protein toxicity. This concise and yet thorough text also discusses using toxin structure as a model for studying structural and functional aspects of protein chemistry. Protein Toxins in Modeling Biochemistry, a SpringerBrief, is essential reading for advanced researchers, scientists and advanced graduate students interested in protein chemistry and related areas of biochemistry and molecular science.
Author: K. Aktories
Publisher: Springer Science & Business Media
ISBN: 3662059711
Category : Medical
Languages : en
Pages : 713
Get Book Here
Book Description
In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes (pore formation) or stimulating cell receptors (superantigens). This is the most current reference work on these important bacterial protein toxins, which are presented from the point of view of different disciplines such as pharmacology, microbiology, cell biology and protein chemistry.
Author: Joseph E. Alouf
Publisher: Elsevier
ISBN: 0080456987
Category : Science
Languages : en
Pages : 1072
Get Book Here
Book Description
This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. - Edited by two of the most highly regarded experts in the field from the Institut Pasteur, France - 14 brand new chapters dedicated to coverage of historical and general aspects of toxinology - Includes the major toxins of both basic and clinical interest are described in depth - Details applied aspects of toxins such as therapy, vaccinology, and toolkits in cell biology - Evolutionary and functional aspects of bacterial toxins evaluated and summarized - Toxin applications in cell biology presented - Therapy (cancer therapy, dystonias) discussed - Vaccines (native and genetically engineered vaccines) featured - Toxins discussed as biological weapons, comprising chapters on anthrax, diphtheria, ricin etc.
Author: Joel Moss
Publisher: CRC Press
ISBN: 1482273209
Category : Medical
Languages : en
Pages : 656
Get Book Here
Book Description
This volume describes the structure and function of bacterial toxins and presents a comprehensive review of virulence factors, providing recent information concerning cell physiology and biochemistry, as well as new toxin tools for experimental studies and clinical therapy. A wide variety of toxic proteins, including the toxins that cause diptheria
Author: Bal Ram Singh
Publisher: Cambridge University Press
ISBN: 1108486401
Category : Medical
Languages : en
Pages : 378
Get Book Here
Book Description
The book will be useful for undergraduate students as a supplementary/reference text in the field of molecular biotechnology.
Author: Paul H. Naccache
Publisher: CRC Press
ISBN: 9780849345722
Category : Medical
Languages : en
Pages : 170
Get Book Here
Book Description
Calcium Signaling provides a review of the salient points of knowledge relating G proteins to calcium mobilization in a variety of cells including blood cells, (e.g. platelets, neutrophils, lymphocytes) liver, pancreas, cardiac tissue, pituitary cells, olfactory cilia, photoreceptors and the major elements of the transmembrane transduction processes is an important addition to the libraries of biological chemists, cell biologists, physiologists, pharmacologists and biophysicists among others.
Author: Ralph A. Bradshaw
Publisher: Academic Press
ISBN: 0080920918
Category : Science
Languages : en
Pages : 3188
Get Book Here
Book Description
Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. - Contains over 350 chapters of comprehensive coverage on cell signaling - Includes discussion on topics from ligand/receptor interactions to organ/organism responses - Provides user-friendly, well-illustrated, reputable content by experts in the field
Author: David Evered
Publisher: John Wiley & Sons
ISBN: 0470718633
Category : Medical
Languages : en
Pages : 192
Get Book Here
Book Description
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Author: Khalid Mahmood Zia
Publisher: Elsevier
ISBN: 0128168900
Category : Technology & Engineering
Languages : en
Pages : 602
Get Book Here
Book Description
Bionanocomposites: Green Synthesis and Applications provides an in-depth study on the synthesis of a variety of bionanocomposites from different types of raw materials. In addition, the book offers an overview on the synthesis and applications of environmentally friendly bionanocomposites, with an emphasis on bionanocomposites of natural products. Final sections focus on various characterization techniques, their production, and the future prospects of sustainable bionanocomposites. - Outlines the major characterization methods and processing techniques for bionanocomposites - Explores how bionanocomopsites are being used to design new projects in medicine and environmental engineering - Discusses how the properties of a variety of bionanocomposite classes make them suitable for particular industrial applications
Author: Klaus Aktories
Publisher: Springer Science & Business Media
ISBN: 3642769667
Category : Medical
Languages : en
Pages : 154
Get Book Here
Book Description
ADP-ribosylating toxins have been the focus of intensive research for more than 30 years. Researchers from diverse fields of science have taken an interest in these bacterial toxins; they are studied, for example, by microbiologists, biochemists, cell biologists, and pharmacologists. There are two principal reasons for the broad and still growing interest in ADP ribosylating toxins. First, insights into the structure and functions of the toxins might be the key to prevention and treatment of diseases caused by the toxin-producing infectious micro organisms. Second, the ADP-ribosylating toxins provide potent and often unique pharmacological tools for the study of the physiological functions of their target proteins. The latter is especially the case with cholera and pertussis toxins, which both modify the IX-subunits of heterotrimeric G-proteins involved in signal transduction pathways. These toxins have proved invaluable in extending our basic understanding of the regulation of hormone-controlled signal transduction. This volume provides a review and an update of recent studies on the basic properties of bacterial ADP-ribosylating tbxins and/or exoenzymes. Our current knowledge of the cel lular entry mechanisms of ADP-ribosylating toxins is reviewed by MADSHUS and STENMARK. WILSON and COLLIER then deal with recent insights into the enzyme mechanism and active site structure of diphtheria toxin and Pseudomonas aeruginosa exotoxin A, which modify elongation factor 2. Toxins which ADP-ribosylate heterotrimeric G-proteins involved in trans membrane signal transduction are the subject of the next two chapters.
