Principles and Practices of Biological Mass Spectrometry

Principles and Practices of Biological Mass Spectrometry PDF Author: Chhabil Dass
Publisher: John Wiley & Sons Incorporated
ISBN: 9780470546024
Category : Science
Languages : en
Pages : 500

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Book Description
This book provides professionals in the biological sciences with a solid basis in the fundamentals of contemporary mass spectrometry so that they can confidently choose and apply the best instrumentation and experimental approaches for their needs. The only single-volume guide of its kind, the book offers comprehensive coverage of various aspects of the latest instrumentation (including ionization methods, mass analyzers, detectors, tandem MS, and hyphenated techniques), techniques used in the analysis of important classes of biological materials such as peptides, proteins, lipids, carbohydrates, and oligonucleotides, and applications to real-world problems.

Principles and Practices of Biological Mass Spectrometry

Principles and Practices of Biological Mass Spectrometry PDF Author: Chhabil Dass
Publisher: John Wiley & Sons Incorporated
ISBN: 9780470546024
Category : Science
Languages : en
Pages : 500

Get Book Here

Book Description
This book provides professionals in the biological sciences with a solid basis in the fundamentals of contemporary mass spectrometry so that they can confidently choose and apply the best instrumentation and experimental approaches for their needs. The only single-volume guide of its kind, the book offers comprehensive coverage of various aspects of the latest instrumentation (including ionization methods, mass analyzers, detectors, tandem MS, and hyphenated techniques), techniques used in the analysis of important classes of biological materials such as peptides, proteins, lipids, carbohydrates, and oligonucleotides, and applications to real-world problems.

Principles and Practice of Biological Mass Spectro Metry

Principles and Practice of Biological Mass Spectro Metry PDF Author: Dass
Publisher:
ISBN: 9780471231899
Category :
Languages : en
Pages :

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Book Description


Principles and Practice of Biological Mass Spectrometry

Principles and Practice of Biological Mass Spectrometry PDF Author: Chhabil Dass
Publisher: Wiley-Interscience
ISBN: 9780471330530
Category : Science
Languages : en
Pages : 448

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Book Description
A practical introduction to contemporary instrumentation, techniques, and applications This book provides professionals in the biological sciences with a solid basis in the fundamentals of contemporary mass spectrometry so that they can confidently choose and apply the best instrumentation and experimental approaches for their needs. The only single-volume guide of its kind, Principles and Practice of Biological Mass Spectrometry offers comprehensive coverage of the latest instrumentation, techniques, and applications in the rapidly expanding field of biological mass spectrometry, making it an excellent working resource for experts and novices alike. Principles and Practice of Biological Mass Spectrometry begins with a detailed review of the fundamentals of and recent developments in biological mass spectrometry instrumentation. This is followed by practical, well-illustrated instances of important mass spectrometric techniques, including: * Tandem mass spectrometry * Collision-induced dissociation * Molecular mass determination * Coupling of mass spectrometry with separation techniques * Quantification The final portion of the book is devoted to an exploration of contemporary approaches to the characterization of the various classes of compounds relevant to the biological sciences. While the emphasis is on proteins and peptides, nucleic acid, carbohydrates, and lipids, pharmaceutical drugs and metabolites also receive extensive coverage. Throughout, coverage is generously supplemented with examples of applications across a wide range of commercial and academic venues. Principles and Practice of Biological Mass Spectrometry is an invaluable working resource for chemists, biochemists, biologists, molecular biologists, biomedical researchers, pharmacologists, immunologists, forensic scientists, environmental scientists, and all whose research involves the analysis of biological compounds.

Mass Spectrometry Imaging

Mass Spectrometry Imaging PDF Author: Stanislav S. Rubakhin
Publisher: Humana Press
ISBN: 9781607617457
Category : Science
Languages : en
Pages : 0

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Book Description
Mass spectrometry (MS) offers unmatched capabilities for the detection, characterization, and identification of a broad range of analytes. Mass spectrometry imaging (MSI) integrates MS data with information on the spatial distributions of the analytes, further enhancing the applicability of MS. In Mass Spectrometry Imaging: Principles and Protocols, expert practitioners from academia, industry, and the clinic contribute cutting-edge protocols describing the application of MSI to investigations of analyte localization in a variety of specimens, from microorganisms to plant and animal tissues. Divided into three sections, this volume presents the principles of MS, current and future trends of MSI, and qualitative and quantitative protocols to measure and identify endogenous metabolites and xenobiotics. An array of MSI approaches and technologies for characterizing peptide and protein distributions are described in detail. Written in the highly successful Methods in Molecular BiologyTM series format, protocol chapters include introductions to their respective topics, lists of the necessary materials and reagents, and step-by-step, readily reproducible laboratory procedures. Also included are notes providing tips to avoid experimental pitfalls and helpful suggestions for method troubleshooting. Comprehensive and up-to-date, Mass Spectrometry Imaging: Principles and Protocols is written for scientists, biological and chemical engineers, and clinicians who are interested in applying MSI in their work and those who would benefit from having detailed experimental guidelines available in a single, convenient source.

Principles and Practice of Bioanalysis

Principles and Practice of Bioanalysis PDF Author: Richard F. Venn
Publisher: CRC Press
ISBN: 9780748408429
Category : Medical
Languages : en
Pages : 392

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Book Description
Principles and Practice of Bioanalysis provides a guide to the methods available and the techniques currently used in this field. It provides up to the minute information and guidance on the methods and strategy used in developing and running ultra-trace analyses for drugs, metabolites and other substances. The authors writes in an informal and didactic style, offering a logical path through the problems of small molecule (bio)analysis and enables readers to choose appropriate methods of analysis for their needs. Principles and Practice of Bioanalysis provides an overview of analytical methods for analytical scientists within the pharmaceutical industry, research and development, the agrochemical industry, and scientists in the health service, biology and biochemistry. It also gives postgraduate students a useful reference for their research methods.

Mass Spectrometry Imaging

Mass Spectrometry Imaging PDF Author: Stanislav S. Rubakhin
Publisher: Humana Press
ISBN: 9781617796968
Category : Science
Languages : en
Pages : 490

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Book Description
Mass spectrometry (MS) offers unmatched capabilities for the detection, characterization, and identification of a broad range of analytes. Mass spectrometry imaging (MSI) integrates MS data with information on the spatial distributions of the analytes, further enhancing the applicability of MS. In Mass Spectrometry Imaging: Principles and Protocols, expert practitioners from academia, industry, and the clinic contribute cutting-edge protocols describing the application of MSI to investigations of analyte localization in a variety of specimens, from microorganisms to plant and animal tissues. Divided into three sections, this volume presents the principles of MS, current and future trends of MSI, and qualitative and quantitative protocols to measure and identify endogenous metabolites and xenobiotics. An array of MSI approaches and technologies for characterizing peptide and protein distributions are described in detail. Written in the highly successful Methods in Molecular BiologyTM series format, protocol chapters include introductions to their respective topics, lists of the necessary materials and reagents, and step-by-step, readily reproducible laboratory procedures. Also included are notes providing tips to avoid experimental pitfalls and helpful suggestions for method troubleshooting. Comprehensive and up-to-date, Mass Spectrometry Imaging: Principles and Protocols is written for scientists, biological and chemical engineers, and clinicians who are interested in applying MSI in their work and those who would benefit from having detailed experimental guidelines available in a single, convenient source.

Sample Preparation in Biological Mass Spectrometry

Sample Preparation in Biological Mass Spectrometry PDF Author: Alexander R. Ivanov
Publisher: Springer Science & Business Media
ISBN: 9400708289
Category : Science
Languages : en
Pages : 1081

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Book Description
The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.

Principles and Applications of Clinical Mass Spectrometry

Principles and Applications of Clinical Mass Spectrometry PDF Author: Nader Rifai
Publisher: Elsevier
ISBN: 0128160640
Category : Science
Languages : en
Pages : 218

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Book Description
Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field

Mass Spectrometry

Mass Spectrometry PDF Author: Jürgen H Gross
Publisher: Springer Science & Business Media
ISBN: 3540407391
Category : Science
Languages : en
Pages : 534

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Book Description
Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Principles of Proteomics

Principles of Proteomics PDF Author: Richard Twyman
Publisher: Garland Science
ISBN: 131775302X
Category : Medical
Languages : en
Pages : 281

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Book Description
Principles of Proteomics, Second Edition, provides a concise and user-friendly introduction to the diverse technologies used for the large-scale analysis of proteins, as well as their applications, and their impact in areas such as drug discovery, agriculture, and the fight against disease. Proteomics is a fast-advancing field in which researchers seek to capture all the proteins in the cell and characterize them in ever more detail. Principles of Proteomics has been fully updated to reflect the most recent developments in the field without losing its focus on the underlying principles. With worked examples, case studies profiling both established and emerging technologies, and further reading lists for each chapter, Principles of Proteomics is an ideal introduction for students, researchers and those working in the industry.