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Author: Youqing Shen
Publisher: Royal Society of Chemistry
ISBN: 184973738X
Category : Technology & Engineering
Languages : en
Pages : 331
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Book Description
Interest in the application of nanotechnology to medicine has surged in recent years and could transform the way we diagnose, treat and prevent diseases such as cancer. However, the clinical success of nanomedicine is limited because of problems with toxicity and therapeutic efficacy. To overcome this it is essential to produce new nanosystems with specific functions, which can be achieved by designing new polymers with particular properties that can be used for nanomedicine. Functional Polymers for Nanomedicine provides a complete overview of the different strategies for designing polymers for nanomedicine applications. The first part of the book looks at the current problems and direction in nanomedicine including a review of current design and targeting of nanocarriers. The second part explores the design of polymers with different functions including hyperbranched polymers, polymersomes, polysaccharides, polymeric micelles and zwitterionic polymers and their applications in gene therapy and drug delivery. This timely book is edited by a leading scientist in nanomedicine and provides a suitable introduction and reference source for advanced undergraduates, postgraduates and academic and industrial researchers in polymer science, nanotechnology and pharmacy interested in materials for medical applications.
Author: Shigeru Kunugi
Publisher: Springer Science & Business Media
ISBN: 3642278558
Category : Technology & Engineering
Languages : en
Pages : 290
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Book Description
Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery, by Ernst Wagner Biodegradable Nanoparticles as Vaccine Adjuvants and Delivery Systems: Regulation of Immune Responses by Nanoparticle-Based Vaccine, by Takami Akagi, Masanori Baba and Mitsuru Akashi Biodegradable Polymeric Assemblies for Biomedical Materials, by Yuichi Ohya, Akihiro Takahashi and Koji Nagahama PEGylation Technology in Nanomedicine, by Yutaka Ikeda and Yukio Nagasaki Cytocompatible Hydrogel Composed of Phospholipid Polymers for Regulation of Cell Functions, by Kazuhiko Ishihara, Yan Xu and Tomohiro Konno Design of Biointerfaces for Regenerative Medicine, by Yusuke Arima, Koichi Kato, Yuji Teramura and Hiroo Iwata Advances in Tissue Engineering Approaches to Treatment of Intervertebral Disc Degeneration: Cells and Polymeric Scaffolds for Nucleus Pulposus Regeneration, by Jeremy J. Mercuri and Dan T. Simionescu Functionalized Biocompatible Nanoparticles for Site-Specific Imaging and Therapeutics, by Ranu K. Dutta, Prashant K. Sharma, Hisatoshi Kobayashi and Avinash C. Pandey
Author: Nerea Casado
Publisher: Royal Society of Chemistry
ISBN: 1788018710
Category : Science
Languages : en
Pages : 575
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Book Description
Redox Polymers for Energy and Nanomedicine highlights trends in the chemistry, characterization and application of polymers with redox properties.
Author: Sangamesh G. Kum bar
Publisher: Newnes
ISBN: 0123972906
Category : Technology & Engineering
Languages : en
Pages : 421
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Book Description
Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. - Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials - Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. - 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future
Author: Vishnu Kirthi Arivarasan
Publisher: Springer Nature
ISBN: 3030610217
Category : Science
Languages : en
Pages : 274
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Book Description
Nanomedicine is the field of science that deals with organic applications of medicine at the nano-scale level. It primarily addresses finding, anticipating, and treating sickness, as well as using nanotechnology to assist in controlling human frameworks at the cellular level. The nature of nanotechnology allows it to address numerous medical issues in humans. This book offers comprehensive information to better comprehend and apply multifunctional nanoparticles in nanomedicine, and thus open avenues in the field. Medicating at the nanolevel is an exceptional therapeutic avenue, as it avoids symptoms associated with conventional medicines. This book investigates recent insights into structuring novel drug delivery frameworks. It concentrates on the physical characteristics of drug delivery transporters, and the preliminary procedures involved in their use. The book offers in-depth detail that benefits academics and researchers alike, containing broad research from experts in the field, and serves as a guide for students and researchers in the field of nanomedicine, drug delivery, and nanotechnology.
Author: Christine Vauthier
Publisher: Springer
ISBN: 3319414216
Category : Medical
Languages : en
Pages : 649
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Book Description
This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.
Author: Vladimir Torchilin
Publisher: CRC Press
ISBN: 1000067076
Category : Technology & Engineering
Languages : en
Pages : 319
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Book Description
In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of polymeric nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. Beginning with the combinatorial approach for polymer design, it discusses star-shaped amphiphilic polymers, self-assembling polymer–drug conjugates, amphiphilic dendrimers, dendrimer nanohybrids, sustainable green polymeric nanoconstructs, chitosan-based nanogels, and multifunctional hybrid nanogels. The book provides all available information about these materials and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully.
Author: Prashant Kesharwani
Publisher: Academic Press
ISBN: 0128173319
Category : Medical
Languages : en
Pages : 434
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Book Description
Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. - Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy - Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer - Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles
Author: Ravin Narain
Publisher: Woodhead Publishing
ISBN: 0081005210
Category : Science
Languages : en
Pages : 303
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Book Description
Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. - Explores current challenges in the research of genetic diseases - Discusses polymers for gene therapy and their function in designing advanced materials - Provides examples of organic and inorganic nanomaterials for gene therapy - Includes labeling, targeting, and assays - Looks at characterization, physico-(bio)chemical properties, and applications
Author: Saurabh Bhatia
Publisher: Springer
ISBN: 3319411292
Category : Technology & Engineering
Languages : en
Pages : 235
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Book Description
This book describes 200 bio-polymers, including the most recent and advanced nanotechnology applications. The applications of various bio-medical and other future potential uses are covered and examined in depth. Systematic discussion of current leading natural polymers is also included.
Author: Vladimir Torchilin
Publisher: Pan Stanford Publishing
ISBN: 9814267589
Category : Medical
Languages : en
Pages : 865
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Book Description
The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.
