Photosensitisers in Biomedicine PDF Download
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Author: Mark Wainwright
Publisher: John Wiley & Sons
ISBN: 0470744944
Category : Science
Languages : en
Pages : 296
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Book Description
Photosensitisers in Biomedicine offers clear and comprehensive coverage of the many different photosensitiser types, including information on their many applications that now extend beyond anticancer therapy. These applications now include photoantimicrobial treatments not only in microbial disease, but also in the microbial resistance to conventional drugs, which is circumvented by photomicrobial action. The application of photoantimicrobials in biological fluids is also of considerable importance in the current era of HIV and is discussed in the book. This text offers the most up-to-date coverage of photodynamic therapy including information on how photosensitisers have evolved within the field of cancer therapy and more recently antimicrobial research. There are few books on the market that take the approach of this text, as many are either conference based or focus on the chemistry of photosensitisers. Photosensitisers in Biomedicine is clearly defined into three distinct parts beginning with a clear introduction to the various types of photosensitisers. The book then moves on to discuss the chemistry of photosensitisers and closes with their numerous applications, for example, photodynamic therapy, photodiagnosis, photodynamic antimicrobial chemotherapy (PACT) and other non-oncological applications such as optical, arterial plaques and stents.
Author: Mark Wainwright
Publisher: John Wiley & Sons
ISBN: 0470744944
Category : Science
Languages : en
Pages : 296
Get Book Here
Book Description
Photosensitisers in Biomedicine offers clear and comprehensive coverage of the many different photosensitiser types, including information on their many applications that now extend beyond anticancer therapy. These applications now include photoantimicrobial treatments not only in microbial disease, but also in the microbial resistance to conventional drugs, which is circumvented by photomicrobial action. The application of photoantimicrobials in biological fluids is also of considerable importance in the current era of HIV and is discussed in the book. This text offers the most up-to-date coverage of photodynamic therapy including information on how photosensitisers have evolved within the field of cancer therapy and more recently antimicrobial research. There are few books on the market that take the approach of this text, as many are either conference based or focus on the chemistry of photosensitisers. Photosensitisers in Biomedicine is clearly defined into three distinct parts beginning with a clear introduction to the various types of photosensitisers. The book then moves on to discuss the chemistry of photosensitisers and closes with their numerous applications, for example, photodynamic therapy, photodiagnosis, photodynamic antimicrobial chemotherapy (PACT) and other non-oncological applications such as optical, arterial plaques and stents.
Author: Raymond Bonnett
Publisher: CRC Press
ISBN: 9789056992484
Category : Science
Languages : en
Pages : 332
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Book Description
Photodynamic therapy (PDT) is a ground breaking medical technique which uses lasers to activate light-sensitive chemicals to treat cancer and other diseases without resorting to surgery. For the first time, Chemical Aspects of Photodynamic Therapy introduces in an accessible way the physics, chemistry and biology behind the technique. This highly authoritative account of the account of the rapidly developing field of PDT explores its chemical basis, while presenting information in its historical context. Haematoporphyrin derivative is considered in detail, together with the new 'second generation' photosensitisers , such as chlorins, bacteriochlorins and phthalocyanines. Photosensitisers which are currently in clinical trials are compared and reference is made to new light sources, biological and clinical findings, and prospects for future developments. This book is essential reading for new students and researchers alike studying PDT. It is recommended particularly for photochemists, as well as photobiologists and clinicians. About the author Raymond Bonnett was born in London in 1931. After a spell in the air force, he graduated from Imperial College, going on to Cambridge to research under Alexander Todd and A.W. Johnson and then to Harvard to work with R.B. Woodward. He is now Scotia Research Professor of Chemistry at Queen Mary and Wesfield College, University of London, UK. He has been active in research on photosensitisers for 25 years and has published over 200 papers on the chemistry of porphyrins and related compounds.
Author: Tebello Nyokong
Publisher: Springer Science & Business Media
ISBN: 9048138701
Category : Science
Languages : en
Pages : 672
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Book Description
This book addresses the synthesis of photosensitizers, the main emphasis being on the new methods of synthesis such as microwave, sonochemistry and the use of ionic liquids. It also addresses the photochemistry and photophysics of the photosensitizers alone and in combination with nanoparticles, the use of the photosensitizers in environmental control, safety and medicine. It discusses the common structures of the photosensitizers which are beneficial to these applications.
Author: Galina Zalesskaya
Publisher: Cambridge Scholars Publishing
ISBN: 1527559904
Category : Social Science
Languages : en
Pages : 247
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Book Description
This book explores the molecular mechanism of low-intensity optical radiation action on patients undergoing phototherapy, the use of which has been expanding in recent years. The effect of phototherapy on blood oxygenation, as well as on metabolic processes, is studied here using optical radiation of various wavelengths. The book evaluates changes of blood coagulation, lipid exchange and glucose content, and considers the laws of blood photomodification and the main stages of organism photoactivation. Special attention is also given to the susceptibility of individual patients to blood irradiation and the methods for its control.
Author: David A. Phoenix
Publisher: John Wiley & Sons
ISBN: 3527676155
Category : Medical
Languages : en
Pages : 522
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Book Description
By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, researchers from Europe, the U.S. and Asia cover a broad spectrum of current and potential antimicrobial medications and treatments. The result is a comprehensive survey ranging from small-molecule antibiotics to antimicrobial peptides and their engineered mimetics, from enzymes to nucleic acid therapeutics, from metallic nanoparticles to photo- and sonosensitizers and to phage therapy. In each case, the therapeutic approaches are compared in terms of their mechanisms, likelihood to induce resistance, and their efficiency in a global healthcare context. Unrivaled knowledge for professionals in fundamental research, pharmaceutical development and clinical practice.
Author: Sheba R. David
Publisher: Cambridge Scholars Publishing
ISBN: 1527588556
Category : Medical
Languages : en
Pages : 350
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Book Description
Healthcare has long been on a quest for a ‘magic bullet’ to cure the dreaded disease cancer. As this book shows, nanoparticles perfectly fit the bill with their promising characteristics. Meticulously engineered nanostructures, with a useful drug or molecule, target a specific cancer in unique ways. However, as with many targeted systems, the effectiveness of the system needs to be weighed against the adverse effects. The toxicity of nanoparticles has been a worldwide concern, and evidence-based medicine analyses nanostructures for proof of safety and their efficacy in killing cancer cells. This book gives a fresh perspective on a wealth of diverse nanotechnological advances for various cancers.
Author: Abraham J Domb
Publisher: Royal Society of Chemistry
ISBN: 1788018540
Category : Technology & Engineering
Languages : en
Pages : 546
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Book Description
With the need to combat emerging infectious diseases, research around antimicrobial biomaterials and their applications is booming. This book provides the field with a much-needed fundamental overview of the science, addressing the chemistry of a broad range of biomaterial types, and their applications in the biomedical industry. Materials covered include polymers, from those with inherent antimicrobial activity to those that release antimicrobial agents, antimicrobial ceramics and inorganic compounds, such as metal based antimicrobial additives, and the developing field of biomimetic materials, are discussed. Surfaces, coatings and adhesives are covered, whilst the applications of these antimicrobial materials in biomedical applications, from catheters to orthopaedics, dentistry to ophthalmology, are explored. Edited by international leaders and with contributions from the best in the field, this book is the go-to resource for graduates and researchers in biomaterials science, biomedical engineering, chemical engineering, and materials and polymer chemistry.
Author:
Publisher: Elsevier
ISBN: 0323991726
Category : Science
Languages : en
Pages : 544
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Book Description
Biomedical Applications of Inorganic Photochemistry, Volume 80 in the Advances in Inorganic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Photochemical bio-signaling with Ruthenium complexes, Adventures in the photo-uncaging of small molecule bioregulators, Challenges in medicinal inorganic chemistry and best practices to ensure rigor and reproducibility, Strategic Design of Photo-functional Transition Metal Complexes for Targeted Bioimaging and Therapy, Photoactive Manganese carbonyl Complexes with fac-{Mn(CO)3} Moiety: Design, Application, and Potential as Prodrugs in CO Therapy, Mitochondrial Targeting Metal Complexes, and more. Other chapters cover Photoactive Organometallic Compounds with Antimicrobial Properties, Photoactivated platinum anticancer complexes, New ruthenium phthalocyanines liposomal-encapsulated in modulation of nitric oxide and singlet oxygen release: Selectivity cytotoxicity effect on cancerous cell lines, Inorganic Nanoparticles Engineered for Light-Triggered Unconventional Therapies, Mechanistic insight into phot-activation of small inorganic molecules from the biomedical application perspectives, Ruthenium Complexes for Photoactivated Dual Activity: Drug Delivery and Singlet Oxygen Generation, and Leveraging the Photophysical Properties of Rhenium(I) Tricarbonyl Complexes for Biomedical Applications. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Advances in Inorganic Chemistry serials - Updated release includes the latest information on Biomedical Applications of Inorganic Photochemistry
Author: A. N. Chakrabarty
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 408
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Book Description
Contributed papers presented at an international conference held in 1990.
Author: Bettina Basrani
Publisher: Springer
ISBN: 3319164562
Category : Medical
Languages : en
Pages : 325
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Book Description
This book reviews the available information on bacterial disinfection in endodontics, with emphasis on the chemical treatment of root canals based on current understanding of the process of irrigation. It describes recent advances in knowledge of the chemistry associated with irrigants and delivery systems, which is of vital importance given that chemical intervention is now considered one of the most important measures in eliminating planktonic microbes and biofilms from the infected tooth. Recommendations are made regarding concentrations, exposure times and optimal sequences. Possible complications related to the use of the different solutions are highlighted, with guidance on response. In addition, clinical protocols are suggested on the basis of both clinical experience and the results of past and ongoing research. Throughout, a practical, clinically oriented approach is adopted that will assist the practitioner in ensuring successful endodontic treatment.
