Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs

Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs PDF Author: Enno Freye
Publisher: Springer Science & Business Media
ISBN: 9048124484
Category : Medical
Languages : en
Pages : 286

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Book Description
Finally - a book that covers all aspects of the illicit use of cocaine, amphetamines, ecstasy and/or designer drugs such as GHB, written by two experts in their field. The use of these drugs remains a continuous threat in health and medical care delivery, and this book will be an essential asset to the physician who may have to face the evaluation of patients whose use of these drugs compromises an effective treatment plan for other health issues. The book has been conceived to fill the void in existing physician reference materials, and provides a comprehensive review of the theoretical knowledge and scope of pharmacotherapy in individuals who are hooked on a psychoactive substance. While detailed scientific information is obtainable in other major articles, the book's straightforward format and style, along with its illustrations, will make for easy reading as emphasis is put on information specifically related to drugs that occur most abused in today’s society. The information provided is based on clinical practice rather than pure experimental data, which will give the physician more effective tools useful in their daily practice. Many mechanisms of action of abuse are described in detail and references are provided to direct the reader to further sources for additional information. As a special feature, the book incorporates uncluttered tables and charts, which result in immediate clarification of the mode of action on the central nervous system and the reason for misuse, thus avoiding usual long and fatiguing text in common reference books. The book aims to give the reader a clear and concise plan on what to do when being faced with an overdose situation. A well-organized Table of Contents rapidly leads the reader from general pharmacological issues to the specific overdose syndrome and its management. Additionally, significant emphasis is placed on the practical do's and don’ts for physicians, with special reference to the predictive signs of aberrant drug-related behavior and the identification of the drug diverter by using urine drug screening.

Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs

Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs PDF Author: Enno Freye
Publisher: Springer Science & Business Media
ISBN: 9048124484
Category : Medical
Languages : en
Pages : 286

Get Book Here

Book Description
Finally - a book that covers all aspects of the illicit use of cocaine, amphetamines, ecstasy and/or designer drugs such as GHB, written by two experts in their field. The use of these drugs remains a continuous threat in health and medical care delivery, and this book will be an essential asset to the physician who may have to face the evaluation of patients whose use of these drugs compromises an effective treatment plan for other health issues. The book has been conceived to fill the void in existing physician reference materials, and provides a comprehensive review of the theoretical knowledge and scope of pharmacotherapy in individuals who are hooked on a psychoactive substance. While detailed scientific information is obtainable in other major articles, the book's straightforward format and style, along with its illustrations, will make for easy reading as emphasis is put on information specifically related to drugs that occur most abused in today’s society. The information provided is based on clinical practice rather than pure experimental data, which will give the physician more effective tools useful in their daily practice. Many mechanisms of action of abuse are described in detail and references are provided to direct the reader to further sources for additional information. As a special feature, the book incorporates uncluttered tables and charts, which result in immediate clarification of the mode of action on the central nervous system and the reason for misuse, thus avoiding usual long and fatiguing text in common reference books. The book aims to give the reader a clear and concise plan on what to do when being faced with an overdose situation. A well-organized Table of Contents rapidly leads the reader from general pharmacological issues to the specific overdose syndrome and its management. Additionally, significant emphasis is placed on the practical do's and don’ts for physicians, with special reference to the predictive signs of aberrant drug-related behavior and the identification of the drug diverter by using urine drug screening.

Critical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing PDF Author: Amitava Dasgupta
Publisher: Academic Press
ISBN: 0128156082
Category : Science
Languages : en
Pages : 544

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Book Description
Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. - Serves as a ready resource of information for alcohol and drug testing - Ideal resource for making decisions related to the monitoring and interpretation of results - Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Synthetic Cathinones

Synthetic Cathinones PDF Author: Jolanta B. Zawilska
Publisher: Springer
ISBN: 3319787071
Category : Medical
Languages : en
Pages : 215

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Book Description
Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.

Addictions

Addictions PDF Author: Barbara S. McCrady
Publisher: Oxford University Press
ISBN: 0199753660
Category : Medical
Languages : en
Pages : 966

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Book Description
Addictions: A Comprehensive Guidebook, Second Edition, features a roster of senior scientists covering the latest findings in the study of alcohol and other drug use, abuse, and dependence.

Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA

Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA PDF Author: Stephen J. Peroutka
Publisher: Springer Science & Business Media
ISBN: 9780792303053
Category : Medical
Languages : en
Pages : 270

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Book Description
The variety of viewpoints expressed in this book illustrate the many contro versies surrounding MDMA [1]. On the one hand, the proponents ofMDMA use believe this agent offers a unique psychoactive effect that may have important clinical applications, especially in the field of psychotherapy. On the other hand, the scientific data concerning the neurotoxic effects of the drug are unequivocal. The most striking feature of the human information of MDMA is the paucity of data that has been generated on the drug since it was patented in 1914. As pointed out by Beck (Chapter 6) and others, a clear need exists for better epidemiological and clinical data on MDMA. In the absence of such data, arguments both for and against the cotinued use ofMDMA with humans will be difficult to support. Unfortunately, the currently available data must be used to develop rational policies for potential human users of MDMA. At the present time, there are no data indicating that recreational doses of MDMA permanently damage the human brain. Nonetheless, based on a review of the contents of this book as well as on informal discussions with approximately 200 recreational users of MDMA, the following personal observations suggest that MDMA is radically different from other recreational drugs.

Alcohol, Drugs, Genes and the Clinical Laboratory

Alcohol, Drugs, Genes and the Clinical Laboratory PDF Author: Amitava Dasgupta
Publisher: Academic Press
ISBN: 012809334X
Category : Medical
Languages : en
Pages : 238

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Book Description
Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials. - Features accessible language for healthcare and safety professionals who are not experts in laboratory procedures - Provides examples from clinical and everyday situations - Explains how to interpret laboratory results and the latest genetic factors regarding drug and alcohol abuse

Neuropathology of Drug Addictions and Substance Misuse Volume 2

Neuropathology of Drug Addictions and Substance Misuse Volume 2 PDF Author: Victor R Preedy
Publisher: Academic Press
ISBN: 0128003758
Category : Medical
Languages : en
Pages : 1184

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Book Description
Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances. - Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions - Fills an existing gap in the literature by serving as a "one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse - Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references - Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body

The American Psychiatric Publishing Textbook of Substance Abuse Treatment

The American Psychiatric Publishing Textbook of Substance Abuse Treatment PDF Author: Marc Galanter
Publisher: American Psychiatric Pub
ISBN: 1585625183
Category : Medical
Languages : en
Pages : 982

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Book Description
No other text available today offers what The American Psychiatric Publishing Textbook of Substance Abuse Treatment can: completely updated treatment information on a broad range of substance use disorders that is consistent with the new DSM-5 classification and thus reflective of how psychiatry is practiced today. Designed for researchers and mental health professionals ranging from trainee to licensed practitioner, the book is also appropriate for a diverse array of rehabilitation settings, from inpatient to community-based treatment. Full coverage is provided on 12-step programs, as well, including the latest outcomes research. Much of the material is new to this edition: A chapter has been added on science in the treatment of substance abuse, in which the authors discuss the history of scientific intervention in substance abuse and explore what happens to the brain when addicting drugs are consumed, review animal models and imaging techniques, and discuss current progress in the science of addiction. Chapters have been added on screening and brief intervention, reflecting the development of brief screening tools and research on the efficacy of interventions, and the role of "recovery" in chronic care disease management -- specifically what the treatment models for alcohol dependence and for diabetes can effectively borrow from each other. A new chapter focuses on the treatment of alcohol intoxication and withdrawal -- the first steps in treatment of alcohol use disorder. Two chapters on marijuana -- one on the neurobiology and one addressing treatment have been added. Given the accelerating trend toward decriminalization and legalization of this substance, clinicians will find this information of increasing importance. The section on substance use issues among gay men and lesbians has been expanded to include bisexual and transgender people in recognition of increased diversity among the population. Well-structured, with topics that follow logically and many practical, treatment-oriented features, such as quick reference tables and lists of recommended readings, The American Psychiatric Publishing Textbook of Substance Abuse Treatment is a classic that will enhance the education and practice of clinicians.

Novel Psychoactive Substances

Novel Psychoactive Substances PDF Author: Paul I. Dargan
Publisher: Academic Press
ISBN: 0128190302
Category : Medical
Languages : en
Pages : 556

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Book Description
Novel Psychoactive Substances: Classification, Pharmacology and Toxicology, Second Edition provides readers with a comprehensive examination on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." The book covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance and a discussion of their associated acute and chronic harm and toxicity. This second edition addresses drugs new to the scene, with completely updated and revised chapters. Written by international experts in the field, this multi-authored book is an essential reference for scientists, clinicians, academics, and regulatory and law enforcement professionals. - Includes chapters written by international experts in the field - Presents a comprehensive overview on the classification, detection, availability and supply of novel psychoactive substances, in addition to the pharmacology and toxicology associated with the substance - Offers a single source for all interested parties working in this area, including scientists, academics, clinicians, law enforcement and regulatory agencies - Provides a full treatment of novel psychoactive substances that have recently emerged onto the recreational drug scene, including amphetamines and the synthetic cannabinoid receptors in 'spice' and 'K2'

Cocaine and Other Stimulants

Cocaine and Other Stimulants PDF Author: Everett Ellinwood
Publisher: Springer
ISBN: 9781468430899
Category : Medical
Languages : en
Pages : 0

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Book Description
This volume contains a collection of articles that were presented at a conference on contemporary issues in stimulant research held at Duke University Medical Center, November 10-12, 1975.