Pharmaceutical Strategies to Prevent, Treat, and Recover: Advances and Challenges in Ischemic Stroke and Hemorrhagic Stroke PDF Download
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Author: Yuwen Li
Publisher: Frontiers Media SA
ISBN: 2832545432
Category : Science
Languages : en
Pages : 218
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Book Description
Stroke is one of the leading causes of death and disability worldwide. Among them, ischemic stroke is attributed to an abrupt blockage of blood flow to brain, while hemorrhagic stroke is caused by bleeding into brain. The principal aim of stroke therapy is to decrease mortality and reduce persistent neurologic injury and long-term disability. It also targets to prevent complications and recurrence after stroke as well as minimize the brain function loss caused by the cerebral damage. Fortunately, many strokes could be prevented through healthy lifestyle changes and controlling stroke risk factors, such as cigarette or tobacco smoking, high blood pressure, diabetes, and heart disease. Carotid endarterectomy and stenting of the cervical and intracranial vessels may help reduce recurrent stroke in some cases. Advanced treatments and rehabilitation are helping many stroke patients return to society and their families.
Author: Yuwen Li
Publisher: Frontiers Media SA
ISBN: 2832545432
Category : Science
Languages : en
Pages : 218
Get Book Here
Book Description
Stroke is one of the leading causes of death and disability worldwide. Among them, ischemic stroke is attributed to an abrupt blockage of blood flow to brain, while hemorrhagic stroke is caused by bleeding into brain. The principal aim of stroke therapy is to decrease mortality and reduce persistent neurologic injury and long-term disability. It also targets to prevent complications and recurrence after stroke as well as minimize the brain function loss caused by the cerebral damage. Fortunately, many strokes could be prevented through healthy lifestyle changes and controlling stroke risk factors, such as cigarette or tobacco smoking, high blood pressure, diabetes, and heart disease. Carotid endarterectomy and stenting of the cervical and intracranial vessels may help reduce recurrent stroke in some cases. Advanced treatments and rehabilitation are helping many stroke patients return to society and their families.
Author: Bruce Ovbiagele
Publisher: Springer
ISBN: 3319177508
Category : Medical
Languages : en
Pages : 321
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Book Description
This complete resource captures state-of-the-art strategies and the accelerated pace of discovery that is revolutionizing what is known about ischemic stroke and its treatment. Therapeutics for acute management, secondary prevention, recovery, rehabilitation, asymptomatic cerebral ischemia, and implementation of stroke systems of care are all discussed in this comprehensive yet practical guide. Chapters are authored by leading academicians with extensive clinical practice experience from all over the world and feature the scientific evidence behind prevailing therapeutic strategies for managing ischemic cerebrovascular disease. The specialist or general practitioner will gain critical knowledge in stroke management, current clinical challenges and promising new therapies under investigation.
Author: Syed Shadab Raza
Publisher: Springer Nature
ISBN: 9811685622
Category : Medical
Languages : en
Pages : 360
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Book Description
This book illustrates the importance and significance of regenerative medicine in stroke recovery. It discusses stem-cell-based treatment strategies and offers mechanistic insights into their role in neurological recovery. It also examines the challenges and advances in using adult stem cells for enhanced therapeutic efficacy. Further, it presents the strategies as well as the strengths and weaknesses of various delivery methods to administer stem cells in ischemic stroke. It examines the role of non-coding RNA in our understanding the stroke pathogenesis, their regulatory role in ischemic stroke and potential as biomarkers and therapeutic targets. Lastly, it explores exosomes in the treatment of stroke, and the underlying mechanism of their action as therapeutic vectors for stroke. Given its scope, it is an excellent resource for neurologists, neuroscientists and researchers involved in regenerative therapy for stroke.
Author: Scott Eric Kasner
Publisher: Butterworth-Heinemann
ISBN: 9780750674645
Category : Brain
Languages : en
Pages : 446
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Book Description
This volume covers prevention and treatment options for both primary and secondary ischemic stroke; offers practical, scientific guidance on all aspects of patient care, including critical care management and rehabilitation; provides author recommendations where clinical answers are not yet clear; and discusses topics such as diagnostic evaluation of TIA and ischemic stroke, large vessel atherosclerosis, small vessel occlusive disease, ususual and cryptogenic etiologies of stroke, and emerging therapies.
Author: Justin A. Zivin
Publisher: Oxford University Press
ISBN: 0195393929
Category : Health & Fitness
Languages : en
Pages : 206
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Book Description
TPA for Stroke: The Story of a Controversial Drug explains the drug's beginnings within pharmaceutical giant Genentech, and its eventual marginalization due to a convergence of unfortunate political, fiscal, and medical circumstances.
Author: R. Gilberto González
Publisher: Springer Science & Business Media
ISBN: 3642127517
Category : Medical
Languages : en
Pages : 299
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Book Description
This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
Author: David Spence
Publisher: McGraw Hill Professional
ISBN: 0071766766
Category : Medical
Languages : en
Pages : 321
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Book Description
***IF YOU WANT TO UPDATE THE INFORMATION ON YOUR TITLE SHEET, THEN YOU MUST UPDATE COPY IN THE "PRODUCT INFORMATION COPY" FIELD. COPY IN THE "TIPSHEET COPY" FIELD DOES NOT APPEAR ON TITLE SHEETS.*** This book arms any physician with the evidence and tools they need to help patients who have had or at risk of having a stroke in preventing stroke. Market / Audience PRIMARY: Neurologists (18,000 in US) Cardiologists (30,000 in US) SECONDARY: Internists (200,00) About the Book Stroke is the third leading cause of death in the US (with cardiac disease and cancer being number one and two). Annually, 795,000 people in the US suffer a new or recurrent stroke. Approximately 140,000 people die from stroke each year, a figure that has been declining because of what we have learned about daily aspirin, smoking cessation, diet, and surgical procedures to prevent new or recurrent strokes. The 6 million patients alive today who've survived stroke are at the highest risk, yet anyone of a certain age or who has had a "mini-storke," is at higher risk. While more is known than ever about how to prevent stroke, there is still great variability in how stroke prevention is implemented regionally. Challenges in getting patients to comply with stroke prevention measures are also a concern. This book provides an evidence-based approach and practical tools to help any physician help their patients avoid a new or a recurrant stroke. Key Selling Features Makes stroke prevention easy to teach, and easy to comply with. About the Authors David Spence, MD Trained in Neurology with Dr. Barnett before going on to complete training in Internal Medicine, and then a fellowship in Clinical Pharmacology at San Francisco. Has focused on stroke prevention throughout his career. Professor of Neurology and Clinical Pharmacology at the Robarts Research Institute, London, Canada. Ran a hypertension clinic for 20 years; for the past 15 years has run a busy stroke prevention clinic. Pioneered ultrasound measurement of carotid plaque for patient management, genetic research and evaluation of new therapies. Published in 2006 a book for the public; How to prevent your stroke. Wife and first son are family physicians; has done a lot of continuing medical education to family physicians around the world. Selected by the World Congress of Neurology in 2009 to teach the course on stroke prevention. Henry JM Barnett, MD A giant in stroke prevention: first to show that Aspirin reduced the risk of stroke; led the study that showed that carotid endarterectomy reduced the risk of stroke in patients with symptomatic carotid stenosis, and the study that showed that extra-cranial to intracranial bypass was not effective. Founding chair of the department of Clinical Neurological Sciences at the University of Western Ontario, in which Neurology and Neurosurgery joined to form a department separate from Medicine and Surgery. This model, which he pioneered with his neurosurgical colleague Charlie Drake, has been copied successfully the world over. Former editor of the journal Stroke, and internationally recognized as the father of stroke prevention.
Author: Paul A. Lapchak
Publisher: Springer
ISBN: 9783319666785
Category : Medical
Languages : en
Pages : 541
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Book Description
This book discusses recent advances in the field of translational stroke research. The editors have designed the book to provide new insight into the importance of regeneration and repair mechanisms for stroke victims. The editors have brought together a talented group of international stroke researchers and clinicians to contribute to this volume, which is written for students, researchers and physicians in biotechnology, neurosciences, neurology, neuroradiology and neurosurgery. Throughout the world, stroke is still a leading cause of mortality and morbidity; there are 152,000 strokes in the United Kingdom, 62,000 in Canada, and approximately 15 million people worldwide. Large communities of stroke survivors are eagerly awaiting scientific advances in translational stroke research related to regeneration and recovery of function that would offer new therapeutics for rehabilitation and regeneration utilizing novel stem cell and molecular-based approaches. This volume will allow the reader to undersnd the future of stroke treatment from its inception in the laboratory through to clinical trial design. The reader will learn about the recent advances made in these areas related to basic and applied stroke research and their translational potential. Dr. Paul A. Lapchak is Professor of Neurology and Director of Translational Research in the Departments of Neurology & Neurosurgery at Cedars-Sinai Medical Center in Los Angeles CA, USA. Dr. Lapchak is an internationally recognized expert conducting translational drug development research for ischemic and hemorrhagic stroke. Dr. John H. Zhang is Professor of Anesthesiology, Neurosurgery, Neurology, and Physiology, and Director, Center for Neuroscience Research at Loma Linda University School of Medicine, Loma Linda, CA, USA. Dr. Zhang is an internationally recognized expert working on drug development for hemorrhagic stroke.
Author: Kennedy Albert
Publisher: Independently Published
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Medically termed as a cerebrovascular accident (CVA), a stroke is a sudden and possibly fatal disorder caused by a cutoff in blood flow to an area of the brain. Brain injury and other neurological problems may arise from this disruption in blood flow. Two major categories of strokes exist: - Ischemic strokes account for about 85% of all strokes and are therefore the most common form. The brain's blood supply is cut off when a clot or plaque builds up in an artery. Because of this, healthy brain tissue around the afflicted area is deprived of oxygen and dies. - When a blood artery in the brain bursts, it bleeds (hemorrhages) into the brain tissue around it, causing a stroke. Two subtypes of hemorrhagic stroke have been identified. - When a blood vessel in the brain bursts, blood collects in the brain tissue, a condition known as intracerebral hemorrhage. - Bleeding into the subarachnoid space, between the brain and the arachnoid membrane, is called a subarachnoid hemorrhage. Stroke symptoms include sudden confusion, trouble speaking or understanding speech, sudden trouble seeing in one or both eyes, sudden severe headache, difficulty walking, dizziness, loss of balance, or lack of coordination, and numbness or weakness in the face, arm, or leg, especially on one side of the body. When someone is suspected of suffering a stroke, getting them medical assistance quickly is vital to reducing brain damage and increasing their chances of recovery. Ischemic strokes can be treated with anti-clotting drugs, while hemorrhagic strokes may require surgical repair of blood vessel damage followed by rehabilitation to assist the patient restore lost abilities. Stroke prevention techniques include controlling known risk factors including hypertension, diabetes, and smoking, and living a generally healthy life with frequent exercise, a good diet, and moderate alcohol consumption. Getting checkups on a regular basis and treating any underlying health issues right away will greatly lower the likelihood of having a stroke.
Author: Dorairaj Prabhakaran
Publisher: World Bank Publications
ISBN: 1464805202
Category : Medical
Languages : en
Pages : 948
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Book Description
Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.
