Cellular and Molecular Biology PDF Download
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Author:
Publisher:
ISBN:
Category : Cytochemistry
Languages : en
Pages : 416
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Book Description
Author:
Publisher:
ISBN:
Category : Cytochemistry
Languages : en
Pages : 416
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Book Description
Author: M. J. Doenhoff
Publisher: Cambridge University Press
ISBN: 9780521645829
Category : Science
Languages : en
Pages : 192
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Book Description
The papers in this volume draw attention to both new and recent information on the mechanisms employed by infectious pathogens to underpin their survival in the immunocompetent host and to facilitate their transmission between hosts.
Author: G. Mathe
Publisher: Springer Science & Business Media
ISBN: 3642810179
Category : Medical
Languages : en
Pages : 420
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Book Description
I would like to thank all my co-workers who have collaborated with me, from 1963 until now, in biological and clinical research in the field of cancer active immunotherapy, of its immuno prevention and immunorestoration. They will often be quoted in this book. I am particularly grateful to those who have helped me to write it by reviewing some chapters: D. BELPOMME, J. F. DOR~, IRENE FLORENTIN, A. GOUTNER, I. J. Hm, R. HUCHET and MARIE-CHRISTINE SIMMLER. I also thank NICOLE VRIZ, MARIE-CLAUDE SCHNEIDER, FENELLARIsELEY and M. JUVET for their willing and efficient co-operation in the preperation of the manuscript. I am finally grateful to all authors of books or articles who authorized me to reproduce their figures or tables. Paris, April 1976 G. MAT~ Contents Chapter 1. Introduction and Definitions 1 Chapter 2. Biological Basis: Tumour Associated Antigens, the Immune Machinery and Its Behaviour Concerning Cancer Cells 5 2. 1. Tumour-Associated Antigens 5 2. 2. The Immune Machinery 19 2. 2. 1. Humoral Mediated Immunity and Cell Mediated Immunity 19 2. 2. 2. T- and B-Lymphocyte and Monocyte Differen tiation 22 2. 2. 3. T-Lymphocyte Functions 25 2. 2. 4. B-Lymphocyte Functions 30 2. 2. 5. Macrophage Functions 31 2. 2. 6. K-Cell Function 32 2. 3. The Immune Machinery and Cancer Cells 33 2. 3. 1. Mechanisms Involved in Tumour Cell Rejec tion 33 2. 3. 1. 1. In vivo Evidence for Tumour Immunity 33 2. 3. 1. 2.
Author:
Publisher:
ISBN:
Category : Arthritis
Languages : en
Pages : 446
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Book Description
Author: Yiming Meng
Publisher: Frontiers Media SA
ISBN: 283254813X
Category : Science
Languages : en
Pages : 118
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Book Description
Lung cancer is the second most common type of cancer and is the leading cause of cancer death globally. In 2018, almost 2.1 million new cases were diagnosed, accounting for ~12% of the cancer burden worldwide. The malignant stage of lung tumor is known as lung adenocarcinoma, which is most common and is diagnosed in both smokers and non-smokers.There are two main types of lung cancer, non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Genomic studies have indicated that more than 80% of lung malignancies are classified as NSCLC, of which adenocarcinoma is a predominant subtype. Although significant progress has been made in treating tumor with targetable driver mutations, like EGFR mutations, most tumor do not have such mutations and the prognosis remains poor for metastasis stage patients. Platinum doublet chemotherapy has been the mainstay first-line treatment of patients who are diagnosed with metastatic lung adenocarcinoma without a targetable mutation.In recent years, immunotherapy has emerged as a treatment option that has shown strong response in a subset of patients. The immune agents block crucial checkpoints and regulate the immune response, but the tumor cells evade the patient’s immune systems. By blocking these receptor–ligand interactions, a particular subset of T cells is activated to recognize and respond to tumor cells. While such responses to immunotherapy are promising, they have only been effective in ~20% of patients.
Author: Yunfei Xu
Publisher: Frontiers Media SA
ISBN: 2832540376
Category : Medical
Languages : en
Pages : 355
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Book Description
Hepatic-biliary-pancreatic cancers, mainly including hepatocellular carcinoma, cholangiocarcinoma, gallbladder cancer, are highly aggressive malignancies with few treatment options and poor prognoses. Effects of the traditional systemic treatments such as chemotherapy and radiotherapy, are quite limited to hepatic-biliary-pancreatic cancers. For the patients who suffer from hepatic-biliary-pancreatic cancer and lose the opportunity of radical surgery, few targeted drugs are available. Even for the drugs in clinical trial, potential drug targets and prognostic biomarkers for hepatic-biliary-pancreatic cancer are less studied compared to other common cancers such as lung cancer. Prognostic biomarker study is the initiation to explore new drug targets and revelation of the underlying mechanisms of tumor progression.
Author: Nima Rezaei
Publisher: Springer
ISBN: 3662464101
Category : Medical
Languages : en
Pages : 522
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Book Description
Cancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. This volume focuses on the immunopathology and immunotherapy of organ cancers in detail. It clearly explains their immunology and describes novel immunotherapy for specific cancers, including pediatric solid tumors, hematologic malignancies, gastrointestinal tumors, skin cancers, bone and connective tissue tumors, central nervous system tumors, lung cancers, genitourinary tract tumors and breast cancers. In so doing, it builds on the previous two volumes in Cancer Immunology, placing basic knowledge on tumor immunology and immunotherapy into a clinical perspective with the aim of educating clinicians on advances in cancer immunology and the most recent approaches in the immunotherapy of various tumors. This translational, clinically oriented book will be of special value to clinical immunologists, hematologists and oncologists.
Author: W.P. Peters
Publisher: Elsevier
ISBN: 008052642X
Category : Medical
Languages : en
Pages : 265
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Book Description
Breast cancer research has never been in such an exciting and hopeful phase as today. From a clinical perspective, the discovery of genetic markers of risk in a proportion of familial breast cancer cases has opened up new vistas for understanding and ultimately preventing this disease. On the other hand, aggressive - even daring - therapies are being proven to be effective against advanced breast cancer. For the breast cancer experimentalist, this is also a time of great advance. Although animal and cell culture breast cancer models have proven to be of great use, there are now increasing opportunities to test the concepts developed in these models in actual clinical samples and cases. It is gratifying to see how well these concepts "translate" into the clinical setting. A very active area of research that is linking the laboratory to the clinic is the dissection of the biology and elucidation of the significance of proliferate breast disease and the identification of true, "high risk" or "preneoplastic" legions within the previously ill-defined spectrum of fibrocystic or benign breast disease. One anticipates that discoveries made here will also lead to earlier detection, intervention and prevention of life-threatening cancer.Even, however, as we look with optimism to the eventual eradication of breast cancer, we are once again forced to face the reality that we have not yet achieved our goal. Thus, we are saddened by the much too premature death of Dr. Helene Smith from breast cancer. Helena's work was at the forefront of efforts to understand the biology of human breast cancer at the molecular level. Her insight, open-mindedness, and refusal to sacrifice relevance for convenience will continue to set the standard for all breast cancer researchers. This volume is dedicated to her memory.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1552
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Book Description
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Author: Chao Liu
Publisher: Frontiers Media SA
ISBN: 2832549942
Category : Medical
Languages : en
Pages : 203
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Book Description
Precision medicine is an emerging practice by which clinicians aim to deliver a personalized treatment program to affected patients based on information gained from their individual clinical and biological profiles. In the context of precise cancer immunotherapy, multi-omics, high-throughput sequencing, big data, and other approaches serve to screen new predictive factors for immunotherapy response and prognosis in cancer patients.
