Author: John Bakeless
Publisher: Courier Corporation
ISBN: 9780486292335
Category : History
Languages : en
Pages : 548
Book Description
Authoritative biography of two great explorers. Danger, hardships, Indian customs and lore, much more. 29 illus. 7 maps.
Lewis and Clark
Author: John Bakeless
Publisher: Courier Corporation
ISBN: 9780486292335
Category : History
Languages : en
Pages : 548
Book Description
Authoritative biography of two great explorers. Danger, hardships, Indian customs and lore, much more. 29 illus. 7 maps.
Publisher: Courier Corporation
ISBN: 9780486292335
Category : History
Languages : en
Pages : 548
Book Description
Authoritative biography of two great explorers. Danger, hardships, Indian customs and lore, much more. 29 illus. 7 maps.
If This Is the Age We End Discovery
Author: Rosebud Ben-Oni
Publisher: Alice James Books
ISBN: 1948579499
Category : Poetry
Languages : en
Pages : 88
Book Description
A fascinating blend of poetry and science, Ben-Oni’s poems are precisely crafted, like a surgeon sewing a complicated stitch. The speaker of the collection falls ill, and takes comfort in exploring the idea of “Efes” which is “zero” in Modern Hebrew, using that nullification to be a means of transformation.
Publisher: Alice James Books
ISBN: 1948579499
Category : Poetry
Languages : en
Pages : 88
Book Description
A fascinating blend of poetry and science, Ben-Oni’s poems are precisely crafted, like a surgeon sewing a complicated stitch. The speaker of the collection falls ill, and takes comfort in exploring the idea of “Efes” which is “zero” in Modern Hebrew, using that nullification to be a means of transformation.
Drug Discovery in Cancer Epigenetics
Author: Gerda Egger
Publisher: Academic Press
ISBN: 0128024925
Category : Science
Languages : en
Pages : 499
Book Description
Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin reader proteins. The first few drugs are already FDA approved and have made their way into clinical settings. This book provides a comprehensive summary of the epigenetic drugs currently available and aims to increase awareness in this area to foster more rapid translation of epigenetic drugs into the clinic. - Highlights the potential of epigenetic alterations in cancer for drug development - Covers the tools and methods for epigenetic drug discovery, preclinical and clinical testing, and clinical implications of epigenetic therapy - Provides important information regarding putative epigenetic targets, epigenetic technologies, networks and consortia for epigenetic drug discovery and routes for translation
Publisher: Academic Press
ISBN: 0128024925
Category : Science
Languages : en
Pages : 499
Book Description
Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin reader proteins. The first few drugs are already FDA approved and have made their way into clinical settings. This book provides a comprehensive summary of the epigenetic drugs currently available and aims to increase awareness in this area to foster more rapid translation of epigenetic drugs into the clinic. - Highlights the potential of epigenetic alterations in cancer for drug development - Covers the tools and methods for epigenetic drug discovery, preclinical and clinical testing, and clinical implications of epigenetic therapy - Provides important information regarding putative epigenetic targets, epigenetic technologies, networks and consortia for epigenetic drug discovery and routes for translation
The Fourth Paradigm
Author: Anthony J. G. Hey
Publisher:
ISBN:
Category : Computers
Languages : en
Pages : 292
Book Description
Foreword. A transformed scientific method. Earth and environment. Health and wellbeing. Scientific infrastructure. Scholarly communication.
Publisher:
ISBN:
Category : Computers
Languages : en
Pages : 292
Book Description
Foreword. A transformed scientific method. Earth and environment. Health and wellbeing. Scientific infrastructure. Scholarly communication.
A Treatise on the Law of Partnership
Author: Nathaniel Lindley Baron Lindley
Publisher: London : Sweet and Maxwell
ISBN:
Category : Partnership
Languages : en
Pages : 1240
Book Description
Publisher: London : Sweet and Maxwell
ISBN:
Category : Partnership
Languages : en
Pages : 1240
Book Description
Oncology Informatics
Author: Bradford W. Hesse
Publisher: Academic Press
ISBN: 0128022000
Category : Computers
Languages : en
Pages : 449
Book Description
Oncology Informatics: Using Health Information Technology to Improve Processes and Outcomes in Cancer Care encapsulates National Cancer Institute-collected evidence into a format that is optimally useful for hospital planners, physicians, researcher, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools. This book is a formational guide for turning clinical systems into engines of discovery as well as a translational guide for moving evidence into practice. It meets recommendations from the National Academies of Science to "reorient the research portfolio" toward providing greater "cognitive support for physicians, patients, and their caregivers" to "improve patient outcomes." Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission, which can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of "Smart and Connected Health." Oncology Informatics is also a policy guide in an era of extensive reform in healthcare settings, including new incentives for healthcare providers to demonstrate "meaningful use" of these technologies to improve system safety, engage patients, ensure continuity of care, enable population health, and protect privacy. Oncology Informatics acknowledges this extraordinary turn of events and offers practical guidance for meeting meaningful use requirements in the service of improved cancer care. Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable. Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice
Publisher: Academic Press
ISBN: 0128022000
Category : Computers
Languages : en
Pages : 449
Book Description
Oncology Informatics: Using Health Information Technology to Improve Processes and Outcomes in Cancer Care encapsulates National Cancer Institute-collected evidence into a format that is optimally useful for hospital planners, physicians, researcher, and informaticians alike as they collectively strive to accelerate progress against cancer using informatics tools. This book is a formational guide for turning clinical systems into engines of discovery as well as a translational guide for moving evidence into practice. It meets recommendations from the National Academies of Science to "reorient the research portfolio" toward providing greater "cognitive support for physicians, patients, and their caregivers" to "improve patient outcomes." Data from systems studies have suggested that oncology and primary care systems are prone to errors of omission, which can lead to fatal consequences downstream. By infusing the best science across disciplines, this book creates new environments of "Smart and Connected Health." Oncology Informatics is also a policy guide in an era of extensive reform in healthcare settings, including new incentives for healthcare providers to demonstrate "meaningful use" of these technologies to improve system safety, engage patients, ensure continuity of care, enable population health, and protect privacy. Oncology Informatics acknowledges this extraordinary turn of events and offers practical guidance for meeting meaningful use requirements in the service of improved cancer care. Anyone who wishes to take full advantage of the health information revolution in oncology to accelerate successes against cancer will find the information in this book valuable. Presents a pragmatic perspective for practitioners and allied health care professionals on how to implement Health I.T. solutions in a way that will minimize disruption while optimizing practice goals Proposes evidence-based guidelines for designers on how to create system interfaces that are easy to use, efficacious, and timesaving Offers insight for researchers into the ways in which informatics tools in oncology can be utilized to shorten the distance between discovery and practice
Sex Addiction: The Partner's Perspective
Author: Paula Hall
Publisher: Routledge
ISBN: 1317660765
Category : Psychology
Languages : en
Pages : 177
Book Description
Sex and pornography addiction are growing problems that devastate the lives of partners as well as sufferers. Sex Addiction: The Partner's Perspective has been written to help partners and those who care about them to survive the shock of discovering their partner is a sex addict and to help them make decisions about the future of their relationships and their lives. First and foremost, it is a practical book, full of facts, and self help exercises to give partners a much needed sense of stability and control. Like its sister book, Understanding and Treating Sex Addiction, it includes case examples and survey results revealing the reality of life for partners of sex addicts. Sex Addiction: The Partner's Perspective is divided into three parts. Part I explores the myths surrounding sex addiction and provides up to date information about what sex addiction is and what causes it before moving on to explain why the discovery hurts partners so much. Part II is about partners’ needs and includes self-help exercises and strategies to help partners regain stability, rebuild self-esteem and consider their future. The controversial topic of co-dependency is also explored with guidance on how to identify it, avoid it and overcome it. Part III focuses on the couple relationship starting with the difficult decision of whether to stay or leave. Whatever the decision, partners will then find help and support for rebuilding trust and reclaiming their sexuality. This book has been written to help partners not only survive, but to grow stronger and move on with their lives – whether alone, or in their relationship. Readers will find revealing statistics and real life stories shared by partners who kindly took part in the first UK survey of sex addiction partners. This book will this book be a valuable guide for partners, but also for the therapists who seek to support them on their journey of recovery.
Publisher: Routledge
ISBN: 1317660765
Category : Psychology
Languages : en
Pages : 177
Book Description
Sex and pornography addiction are growing problems that devastate the lives of partners as well as sufferers. Sex Addiction: The Partner's Perspective has been written to help partners and those who care about them to survive the shock of discovering their partner is a sex addict and to help them make decisions about the future of their relationships and their lives. First and foremost, it is a practical book, full of facts, and self help exercises to give partners a much needed sense of stability and control. Like its sister book, Understanding and Treating Sex Addiction, it includes case examples and survey results revealing the reality of life for partners of sex addicts. Sex Addiction: The Partner's Perspective is divided into three parts. Part I explores the myths surrounding sex addiction and provides up to date information about what sex addiction is and what causes it before moving on to explain why the discovery hurts partners so much. Part II is about partners’ needs and includes self-help exercises and strategies to help partners regain stability, rebuild self-esteem and consider their future. The controversial topic of co-dependency is also explored with guidance on how to identify it, avoid it and overcome it. Part III focuses on the couple relationship starting with the difficult decision of whether to stay or leave. Whatever the decision, partners will then find help and support for rebuilding trust and reclaiming their sexuality. This book has been written to help partners not only survive, but to grow stronger and move on with their lives – whether alone, or in their relationship. Readers will find revealing statistics and real life stories shared by partners who kindly took part in the first UK survey of sex addiction partners. This book will this book be a valuable guide for partners, but also for the therapists who seek to support them on their journey of recovery.
Cycles of Invention and Discovery
Author: Venkatesh Narayanamurti
Publisher: Harvard University Press
ISBN: 0674974158
Category : Science
Languages : en
Pages : 177
Book Description
Cycles of Invention and Discovery offers an in-depth look at the real-world practice of science and engineering. It shows how the standard categories of “basic” and “applied” have become a hindrance to the organization of the U.S. science and technology enterprise. Tracing the history of these problematic categories, Venkatesh Narayanamurti and Toluwalogo Odumosu document how historical views of policy makers and scientists have led to the construction of science as a pure ideal on the one hand and of engineering as a practical (and inherently less prestigious) activity on the other. Even today, this erroneous but still widespread distinction forces these two endeavors into separate silos, misdirects billions of dollars, and thwarts progress in science and engineering research. The authors contrast this outmoded perspective with the lived experiences of researchers at major research laboratories. Using such Nobel Prize–winning examples as magnetic resonance imaging, the transistor, and the laser, they explore the daily micro-practices of research, showing how distinctions between the search for knowledge and creative problem solving break down when one pays attention to the ways in which pathbreaking research actually happens. By studying key contemporary research institutions, the authors highlight the importance of integrated research practices, contrasting these with models of research in the classic but still-influential report Science the Endless Frontier. Narayanamurti and Odumosu’s new model of the research ecosystem underscores that discovery and invention are often two sides of the same coin that moves innovation forward.
Publisher: Harvard University Press
ISBN: 0674974158
Category : Science
Languages : en
Pages : 177
Book Description
Cycles of Invention and Discovery offers an in-depth look at the real-world practice of science and engineering. It shows how the standard categories of “basic” and “applied” have become a hindrance to the organization of the U.S. science and technology enterprise. Tracing the history of these problematic categories, Venkatesh Narayanamurti and Toluwalogo Odumosu document how historical views of policy makers and scientists have led to the construction of science as a pure ideal on the one hand and of engineering as a practical (and inherently less prestigious) activity on the other. Even today, this erroneous but still widespread distinction forces these two endeavors into separate silos, misdirects billions of dollars, and thwarts progress in science and engineering research. The authors contrast this outmoded perspective with the lived experiences of researchers at major research laboratories. Using such Nobel Prize–winning examples as magnetic resonance imaging, the transistor, and the laser, they explore the daily micro-practices of research, showing how distinctions between the search for knowledge and creative problem solving break down when one pays attention to the ways in which pathbreaking research actually happens. By studying key contemporary research institutions, the authors highlight the importance of integrated research practices, contrasting these with models of research in the classic but still-influential report Science the Endless Frontier. Narayanamurti and Odumosu’s new model of the research ecosystem underscores that discovery and invention are often two sides of the same coin that moves innovation forward.
Model Rules of Professional Conduct
Author: American Bar Association. House of Delegates
Publisher: American Bar Association
ISBN: 9781590318737
Category : Law
Languages : en
Pages : 216
Book Description
The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.
Publisher: American Bar Association
ISBN: 9781590318737
Category : Law
Languages : en
Pages : 216
Book Description
The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.
Abbott's Cyclopedic Digest of All the Decisions of All the Courts of New York from the Earlist Time to the Year 1900
Author: De Witt Clinton Blashfield
Publisher:
ISBN:
Category : Law reports, digests, etc
Languages : en
Pages : 1206
Book Description
Publisher:
ISBN:
Category : Law reports, digests, etc
Languages : en
Pages : 1206
Book Description