Paediatric research and development landscape for neglected tropical diseases

Paediatric research and development landscape for neglected tropical diseases PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240101136
Category : Medical
Languages : en
Pages : 13

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Book Description
Neglected tropical diseases (NTDs) are a diverse set of 21 diseases and disease groups that mainly affect resource-poor populations in tropical and subtropical countries. In general, due to limited financial incentives, few new drugs are being developed for NTDs. This Technical Brief provides succinct information on the current R&D situation in terms of treatments for NTDs in children and existing gaps, with a view to addressing these gaps and supporting the research agenda setting.

Paediatric research and development landscape for neglected tropical diseases

Paediatric research and development landscape for neglected tropical diseases PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240101136
Category : Medical
Languages : en
Pages : 13

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Book Description
Neglected tropical diseases (NTDs) are a diverse set of 21 diseases and disease groups that mainly affect resource-poor populations in tropical and subtropical countries. In general, due to limited financial incentives, few new drugs are being developed for NTDs. This Technical Brief provides succinct information on the current R&D situation in terms of treatments for NTDs in children and existing gaps, with a view to addressing these gaps and supporting the research agenda setting.

Shaping the global innovation and access landscape for better paediatric medicines

Shaping the global innovation and access landscape for better paediatric medicines PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240044647
Category : Medical
Languages : en
Pages : 48

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Book Description
GAP-f’s three-year strategic plan (2022-2024) builds from the work undertaken to date by the network of leading partners, both individually and collectively, through GAP-f. With this strategy, GAP-f is excited to increase its footprint into a broader set of diseases to bring it closer to its vision of all children having equitable access to the medicines they need.

Accelerating research, development and access to paediatric medicines

Accelerating research, development and access to paediatric medicines PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240102345
Category : Medical
Languages : en
Pages : 25

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Book Description
The GAP-f Phase 2 Progress Report highlights the network’s achievements and milestones from 2022 to 2024, providing a transparent overview of its impact. The report offers open, transparent, and comprehensive accountability to GAP-f’s partners, supporters, and beneficiaries, highlighting the impact of collaborative initiatives. By showcasing progress, pinpointing areas for continued focus, and sharing insights gained, the report serves as a vital tool for sustaining trust and engagement with stakeholders and guiding the planning and focus of GAP-f’s next strategic phase.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

Investing to Overcome the Global Impact of Neglected Tropical Diseases PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241564865
Category : Medical
Languages : en
Pages : 211

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Book Description
"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

Second meeting of the WHO Strategic and Technical Advisory Group working group on access to safe, efficacious and quality-assured health products for neglected tropical diseases

Second meeting of the WHO Strategic and Technical Advisory Group working group on access to safe, efficacious and quality-assured health products for neglected tropical diseases PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240083030
Category : Medical
Languages : en
Pages : 16

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Book Description
The STAG Working Group on access to safe, efficacious and quality-assured health products for neglected tropical diseases was established in 2021 to facilitate alignment of stakeholders on strategies and best practices for improving access to medicines and other health products for NTDs. The Working Group held its second technical meeting virtually on 19 September 2023. The main outcomes of the meeting were to expand the scope of drug efficacy monitoring to include other neglected tropical diseases and to seek synergy in addressing common issues and challenges across diseases for procurement and supply chain management. In addition to the Working Group’s members, observers, invited guests and the WHO secretariat attended the meeting. This publication contains the report of the meeting and its recommendations to STAG, which will be helpful as a reference and of use to the wider NTD community.

Paediatric drug optimization for neglected tropical diseases

Paediatric drug optimization for neglected tropical diseases PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240085173
Category : Business & Economics
Languages : en
Pages : 56

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Book Description
Priority-setting is the first step to enable a targeted approach to research and development. Developing a prioritized drug portfolio of the most needed formulations for children is essential to streamline researchers’ and supplier’s efforts and resources around specific dosage forms and formulations that address most urgent needs for children. In general, due to limited financial incentives, few new drugs are being developed for Neglected Tropical Diseases (NTDs). Several NTDs disproportionately affect children compared to adults and, as is the case like for most diseases affecting adults and children, the burden to children is compounded by lack of inclusion of paediatric populations in clinical trials and/or lack of age-appropriate dosing regimens and formulations. The PADO-NTD exercise concluded with a final meeting organized in September 2023 with representatives from the four prioritized disease areas to reach consensus on a final PADO-NTD priority list, watch list and research questions and discuss transversal issues for the way forward. The meeting report will include summaries of the background, discussions and deliberations of all PADO exercises, and final conclusions and outputs of the overall PADO for NTD exercises.

Forgotten People, Forgotten Diseases

Forgotten People, Forgotten Diseases PDF Author: Peter J. Hotez
Publisher: John Wiley & Sons
ISBN: 1555818757
Category : Science
Languages : en
Pages : 275

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Book Description
Forgotten People, Forgotten Diseases Second Edition The neglected tropical diseases (NTDs) are the most common infections of the world's poor, but few people know about these diseases and why they are so important. This second edition of Forgotten People, Forgotten Diseases provides an overview of the NTDs and how they devastate the poor, essentially trapping them in a vicious cycle of extreme poverty by preventing them from working or attaining their full intellectual and cognitive development. Author Peter J. Hotez highlights a new opportunity to control and perhaps eliminate these ancient scourges, through alliances between nongovernmental development organizations and private-public partnerships to create a successful environment for mass drug administration and product development activities. Forgotten People, Forgotten Diseases also Addresses the myriad changes that have occurred in the field since the previous edition. Describes how NTDs have affected impoverished populations for centuries, changing world history. Considers the future impact of alliances between nongovernmental development organizations and private-public partnerships. Forgotten People, Forgotten Diseases is an essential resource for anyone seeking a roadmap to coordinate global advocacy and mobilization of resources to combat NTDs.

Blue Marble Health

Blue Marble Health PDF Author: Peter J. Hotez
Publisher: JHU Press
ISBN: 1421420465
Category : Law
Languages : en
Pages : 224

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Book Description
Why do diseases of poverty afflict more people in wealthy countries than in the developing world? In 2011, Dr. Peter J. Hotez relocated to Houston to launch Baylor’s National School of Tropical Medicine. He was shocked to discover that a number of neglected diseases often associated with developing countries were widespread in impoverished Texas communities. Despite the United States’ economic prowess and first-world status, an estimated 12 million Americans living at the poverty level currently suffer from at least one neglected tropical disease, or NTD. Hotez concluded that the world’s neglected diseases—which include tuberculosis, hookworm infection, lymphatic filariasis, Chagas disease, and leishmaniasis—are born first and foremost of extreme poverty. In this book, Hotez describes a new global paradigm known as “blue marble health,” through which he asserts that poor people living in wealthy countries account for most of the world’s poverty-related illness. He explores the current state of neglected diseases in such disparate countries as Mexico, South Korea, Argentina, Australia, the United States, Japan, and Nigeria. By crafting public policy and relying on global partnerships to control or eliminate some of the world’s worst poverty-related illnesses, Hotez believes, it is possible to eliminate life-threatening disease while at the same time creating unprecedented opportunities for science and diplomacy. Clear, compassionate, and timely, Blue Marble Health is a must-read for leaders in global health, tropical medicine, and international development, along with anyone committed to helping the millions of people who are caught in the desperate cycle of poverty and disease.

Rural Development Abstracts

Rural Development Abstracts PDF Author:
Publisher:
ISBN:
Category : Rural development
Languages : en
Pages : 400

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Book Description


Global Health and the Future Role of the United States

Global Health and the Future Role of the United States PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309457637
Category : Medical
Languages : en
Pages : 385

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Book Description
While much progress has been made on achieving the Millenium Development Goals over the last decade, the number and complexity of global health challenges has persisted. Growing forces for globalization have increased the interconnectedness of the world and our interdependency on other countries, economies, and cultures. Monumental growth in international travel and trade have brought improved access to goods and services for many, but also carry ongoing and ever-present threats of zoonotic spillover and infectious disease outbreaks that threaten all. Global Health and the Future Role of the United States identifies global health priorities in light of current and emerging world threats. This report assesses the current global health landscape and how challenges, actions, and players have evolved over the last decade across a wide range of issues, and provides recommendations on how to increase responsiveness, coordination, and efficiency â€" both within the U.S. government and across the global health field.