Free Radicals in Biology V4 PDF Download
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Author: William Pryor
Publisher: Elsevier
ISBN: 0323153720
Category : Science
Languages : en
Pages : 371
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Book Description
Free Radicals in Biology, Volume IV reviews diverse topics in free radical biology and covers topics ranging from radiation biology to lipid peroxidation, radical-mediated liver pathology, and chemical carcinogenesis. Radical mechanisms in prostaglandin biochemistry are also discussed, along with the use of electron spin resonance and spin trap methods to probe mechanisms of radical reactions in biological systems. Comprised of 10 chapters, this volume begins with an overview of the mechanisms of lipid peroxidation, focusing on the chemistry of fluorescent products from in vivo lipid peroxidation; the production of pentane in the expired breath of animals exposed to oxidative threats; and the chemistry of the enzyme glutathione peroxidase. The next chapter is devoted to the kinetic aspects of lipid peroxidation and the multiple ways in which autoxidants can react. The reader is then introduced to the mechanisms of hepatoxicity by synthetic chemicals present in the environment, together with direct mechanisms of radiation damage to nucleic acids. Subsequent chapters deal with spin trapping in biological systems; the role of free radicals in arylamine carcinogenesis and their influence on the structure and reactivity of melanins; and the involvement of vitamin ? and lipid antioxidants in free-radical-initiated reactions. This book will be of value to chemists, biologists, and physicians.
Author: William Pryor
Publisher: Elsevier
ISBN: 0323153720
Category : Science
Languages : en
Pages : 371
Get Book Here
Book Description
Free Radicals in Biology, Volume IV reviews diverse topics in free radical biology and covers topics ranging from radiation biology to lipid peroxidation, radical-mediated liver pathology, and chemical carcinogenesis. Radical mechanisms in prostaglandin biochemistry are also discussed, along with the use of electron spin resonance and spin trap methods to probe mechanisms of radical reactions in biological systems. Comprised of 10 chapters, this volume begins with an overview of the mechanisms of lipid peroxidation, focusing on the chemistry of fluorescent products from in vivo lipid peroxidation; the production of pentane in the expired breath of animals exposed to oxidative threats; and the chemistry of the enzyme glutathione peroxidase. The next chapter is devoted to the kinetic aspects of lipid peroxidation and the multiple ways in which autoxidants can react. The reader is then introduced to the mechanisms of hepatoxicity by synthetic chemicals present in the environment, together with direct mechanisms of radiation damage to nucleic acids. Subsequent chapters deal with spin trapping in biological systems; the role of free radicals in arylamine carcinogenesis and their influence on the structure and reactivity of melanins; and the involvement of vitamin ? and lipid antioxidants in free-radical-initiated reactions. This book will be of value to chemists, biologists, and physicians.
Author: Luis Moroder
Publisher: Royal Society of Chemistry
ISBN: 0854041486
Category : Science
Languages : en
Pages : 453
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Book Description
With contributions from experts in the field, this book provides a comprehensive overview of the oxidative folding of cysteine-rich peptides.
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 84
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Book Description
Author:
Publisher:
ISBN:
Category : Chemistry
Languages : en
Pages : 1576
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Book Description
Author: JOSEPH BRENNER
Publisher: Springer Science & Business Media
ISBN: 1402083750
Category : Philosophy
Languages : en
Pages : 378
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Book Description
This book is both dif?cult and rewarding, affording a new perspective on logic and reality, basically seen in terms of change and stability, being and becoming. Most importantly it exemplifies a mode of doing philosophy of science that seems a welcome departure from the traditional focus on purely analytic arguments. The author approaches ontology, metaphysics, and logic as having offered a number of ways of constructing the description of reality, and aims at deepening their relationships in a new way. Going beyond the mere abstract and formal aspects of logical analysis, he offers a new architecture of logic that sees it as applied not only to the “reasoning processes” belonging to the first disciplinary group – ontology – but also directly concerned with en- ties, events, and phenomena studied by the second one – metaphysics. It is the task of the book to elaborate such a constructive logic, both by offering a lo- cal view of the structure of the reality in general and by proffering a wealth of models able to encompass its implications for science. In turning from the merely formal to the constructive account of logic Brenner overcomes the limitation of logic to linguistic concepts so that it can be not only a logic “of” reality but also “in” that reality which is constitutively characterized by a number of fundamental dualities (observer and observed, self and not-self, internal and external, etc.
Author: Ralf Henkel
Publisher: Academic Press
ISBN: 0128125675
Category : Medical
Languages : en
Pages : 322
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Book Description
Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included. This is a must-have reference in the area of oxidative stress and male reproductive function. - Offers comprehensive information on oxidative stress and its role in male reproduction, including new therapeutic approaches - Deals with current approaches to oxidative stress using OMICS platform - Designed for fertility practitioners, reproductive researchers, and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology
Author: Mary Lou Turgeon
Publisher: Jones & Bartlett Learning
ISBN: 1284294498
Category : Medical
Languages : en
Pages : 779
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Book Description
Clinical Hematology: Theory & Procedures, Enhanced Sixth Edition is a competency-based text with built-in study tools to help you master the theory of clinical hematology and the procedures used to diagnose and treat disorders of the blood and bone marrow.
Author: Stuart H. Orkin
Publisher: Elsevier Health Sciences
ISBN: 0323291775
Category : Medical
Languages : en
Pages : 3517
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Book Description
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
Author: Marc Damelin
Publisher: Springer
ISBN: 3319781545
Category : Medical
Languages : en
Pages : 358
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Book Description
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
Author: M. Abercrombie
Publisher: Academic Press
ISBN: 1483224511
Category : Science
Languages : en
Pages : 461
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Book Description
Advances in Morphogenesis, Volume 1 covers the significant advances in various aspects of morphogenesis. This book is composed of nine chapters that include discussion on cell growth, differentiation, and development. The opening chapter describes the complex process of embryonic organization, from the induction initiation to a number of differentiation processes, leading to formation of the essential part of the axial system of the embryo. The next chapters examine the basic aspects of embryology, the process of regeneration in vertebrate, the suppression of growth processes by morphostatic substances, and the role of proteases in tissue regeneration. These topics are followed by discussions on the factors that control plant cell growth and the morphological, physiological, and biochemical studies of normal pigment cell development and differentiation. The concluding chapters explore the development of limbs of tetrapod vertebrates, the morphogenesis of the vertebrate eye, and the particular phases of teleostean egg development. This book is directed toward developmental biologists.
