Orofacial Pain Biomarkers

Orofacial Pain Biomarkers PDF Author: Jean-Paul Goulet
Publisher: Springer
ISBN: 3662539942
Category : Medical
Languages : en
Pages : 153

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Book Description
This book provides up-to-date information on all aspects of orofacial pain biomarkers. It opens by presenting background information on clinical phenotypes and the neurobiological substrates underlying chronic orofacial pain and by explaining the potential role of biomarkers in the diagnosis, prognostic evaluation, and treatment of orofacial pain. The main section of the book examines the contribution of human and animal studies to the field of biomarkers for orofacial pain and discusses biomarkers for masticatory muscle pain, temporomandibular joint pain, neuropathic face pain, and autonomic nervous system involvement in trigeminal facial pain. The potential impacts of the immune system on orofacial pain biomarkers and candidate gene phenotypes with possible links to chronic orofacial pain conditions are also addressed, and differences and similarities between saliva and serum biomarkers for pain are explained as well. The final section covers research-related issues in assessment methods and statistical analyses used in evaluating biomarkers, identifies future challenges and suggests new directions in the field.

Orofacial Pain Biomarkers

Orofacial Pain Biomarkers PDF Author: Jean-Paul Goulet
Publisher: Springer
ISBN: 3662539942
Category : Medical
Languages : en
Pages : 153

Get Book Here

Book Description
This book provides up-to-date information on all aspects of orofacial pain biomarkers. It opens by presenting background information on clinical phenotypes and the neurobiological substrates underlying chronic orofacial pain and by explaining the potential role of biomarkers in the diagnosis, prognostic evaluation, and treatment of orofacial pain. The main section of the book examines the contribution of human and animal studies to the field of biomarkers for orofacial pain and discusses biomarkers for masticatory muscle pain, temporomandibular joint pain, neuropathic face pain, and autonomic nervous system involvement in trigeminal facial pain. The potential impacts of the immune system on orofacial pain biomarkers and candidate gene phenotypes with possible links to chronic orofacial pain conditions are also addressed, and differences and similarities between saliva and serum biomarkers for pain are explained as well. The final section covers research-related issues in assessment methods and statistical analyses used in evaluating biomarkers, identifies future challenges and suggests new directions in the field.

Orofacial Pain

Orofacial Pain PDF Author: Barry J. Sessle
Publisher: Lippincott Williams & Wilkins
ISBN: 1496331885
Category : Medical
Languages : en
Pages : 573

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Book Description
When it comes to mechanisms, diagnosis, and management of acute and chronic orofacial pain, no book is more comprehensive than Orofacial Pain. With 54 leading pain specialists documenting the latest research advances and treatments, this book is the new standard resource for understanding, assessing, and managing all aspects of orofacial pain. Orofacial Pain’s 24 chapters address the epidemiologic, socioeconomic, and psychological aspects of orofacial pain conditions as well as the mechanisms underlying orofacial pain revealed in recent studies in humans and animals. Most other books on this topic focus on just one or two aspects of orofacial pain—and nearly all with only dental students or clinicians in mind. Orofacial Pain provides the most up-to-date, complete, and integrated coverage of advances in research and new evidence. It is must reading not only for dental clinicians but also for pain scientists and specialists, neurologists, and other clinicians.

Pathological Basis of Oral and Maxillofacial Diseases

Pathological Basis of Oral and Maxillofacial Diseases PDF Author: S. R. Prabhu
Publisher: John Wiley & Sons
ISBN: 1119989205
Category : Medical
Languages : en
Pages : 692

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Book Description
A comprehensive guide for integrating pathology into a clinical setting. Pathological Basis of Oral and Maxillofacial Diseases presents the basic principles involved in disease mechanisms in an easy-to-understand way. By integrating recent advances in molecular, immunologic, and genetic understanding of oral disease, the book helps readers enhance their knowledge and its application in a clinical setting. This book is divided into nine sections, covering key topics such as inflammation, genetic diseases, and neoplasia, with contributions from over 50 international authors. Diagrams, clinical, radiographic, and histopathology images and tables supplement the text, and the editors have ensured a consistent approach throughout. Topics covered in Pathological Basis of Oral and Maxillofacial Diseases include: The influences of nutrition and the environment Cellular structure and function, causes and mechanisms of cellular pathology. Immunity and host defence mechanisms, immune dysfunctions affecting the oro-facial complex. Inflammation and inflammatory diseases of the oro-facial complex Human microbiome, with reference to dysbiosis in dental caries and periodontal diseases Oral manifestations of systemic diseases and the oral-systemic link and its impact on general and oral health Oral potentially malignant and malignant disorders that are a major threat to global public health. Bridging the gap in dental training programs from basic medical science in the initial years to clinical practice, Pathological Basis of Oral and Maxillofacial Diseases is an essential reference for dental students, trainees and practitioners seeking to grasp the pathological basis of disease and apply that knowledge to the oral and maxillofacial regions.

Orofacial Pain

Orofacial Pain PDF Author: Glenn T. Clark
Publisher: John Wiley & Sons
ISBN: 0813815592
Category : Medical
Languages : en
Pages : 408

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Book Description
Orofacial Pain: A Guide to Medications and Management brings together guidance and information on the rational use of medications for the treatment of chronic orofacial pain. Focusing on clinically relevant information throughout and aiming itself squarely at the needs of dentists and other clinicians working directly with orofacial pain, the book covers the use of oral, injectable and topical medications for managing neuropathic and musculoskeletal pain, headache, and uncommon orofacial pain disorders. Useful features, such as discussion of the top 60 medications prescribed for orofacial pain, are integrated with comprehensive coverage of drug types, pharmacolegal issues, and the interaction of medication management with other treatment strategies.

Temporomandibular Disorders

Temporomandibular Disorders PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309670489
Category : Medical
Languages : en
Pages : 427

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Book Description
Temporomandibular disorders (TMDs), are a set of more than 30 health disorders associated with both the temporomandibular joints and the muscles and tissues of the jaw. TMDs have a range of causes and often co-occur with a number of overlapping medical conditions, including headaches, fibromyalgia, back pain and irritable bowel syndrome. TMDs can be transient or long-lasting and may be associated with problems that range from an occasional click of the jaw to severe chronic pain involving the entire orofacial region. Everyday activities, including eating and talking, are often difficult for people with TMDs, and many of them suffer with severe chronic pain due to this condition. Common social activities that most people take for granted, such as smiling, laughing, and kissing, can become unbearable. This dysfunction and pain, and its associated suffering, take a terrible toll on affected individuals, their families, and their friends. Individuals with TMDs often feel stigmatized and invalidated in their experiences by their family, friends, and, often, the health care community. Misjudgments and a failure to understand the nature and depths of TMDs can have severe consequences - more pain and more suffering - for individuals, their families and our society. Temporomandibular Disorders: Priorities for Research and Care calls on a number of stakeholders - across medicine, dentistry, and other fields - to improve the health and well-being of individuals with a TMD. This report addresses the current state of knowledge regarding TMD research, education and training, safety and efficacy of clinical treatments of TMDs, and burden and costs associated with TMDs. The recommendations of Temporomandibular Disorders focus on the actions that many organizations and agencies should take to improve TMD research and care and improve the overall health and well-being of individuals with a TMD.

Contemporary Oral Medicine

Contemporary Oral Medicine PDF Author: Camile S. Farah
Publisher: Springer
ISBN: 9783319723013
Category : Medical
Languages : en
Pages : 0

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Book Description
This book, written by world authorities in the field, is a comprehensive, up-to-date guide to the specialty of Oral Medicine, which is concerned with the diagnosis, prevention, and predominantly non-surgical management of medically related disorders and conditions affecting the oral and maxillofacial region. The pathophysiology, clinical presentation, diagnostic evaluation, and treatment of all relevant diseases and disorders are described with the aid of a wealth of clinical cases and illustrations that enable the reader to appreciate the diversity and potential complexity of Oral Medicine. In addition to the wide-ranging coverage of oral conditions, separate sections are devoted to bone and cutaneous pathology and to orofacial pain and its management, in addition to dental sleep medicine. The clinician who treats Oral Medicine patients will find this book to be an excellent aid to optimal management grounded in a sound knowledge of basic science and the dental and medical aspects of each disorder. In addition, it will serve as an outstanding textbook for undergraduate and postgraduate students.

Machine Learning in Dentistry

Machine Learning in Dentistry PDF Author: Ching-Chang Ko
Publisher: Springer Nature
ISBN: 3030718816
Category : Medical
Languages : en
Pages : 186

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Book Description
This book reviews all aspects of the use of machine learning in contemporary dentistry, clearly explaining its significance for dental imaging, oral diagnosis and treatment, dental designs, and dental research. Machine learning is an emerging field of artificial intelligence research and practice in which computer agents are employed to improve perception, cognition, and action based on their ability to “learn”, for example through use of big data techniques. Its application within dentistry is designed to promote personalized and precision patient care, with enhancement of diagnosis and treatment planning. In this book, readers will find up-to-date information on different machine learning tools and their applicability in various dental specialties. The selected examples amply illustrate the opportunities to employ a machine learning approach within dentistry while also serving to highlight the associated challenges. Machine Learning in Dentistry will be of value for all dental practitioners and researchers who wish to learn more about the potential benefits of using machine learning techniques in their work.

Translational Systems Medicine and Oral Disease

Translational Systems Medicine and Oral Disease PDF Author: Stephen T. Sonis
Publisher: Academic Press
ISBN: 0128137630
Category : Medical
Languages : en
Pages : 460

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Book Description
Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. - Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine - Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases - Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader - Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

Oral Epidemiology

Oral Epidemiology PDF Author: Marco A. Peres
Publisher: Springer Nature
ISBN: 303050123X
Category : Medical
Languages : en
Pages : 534

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Book Description
This intermediate textbook on oral epidemiology is designed to meet the needs of advanced students in the fields of Dentistry and Oral Health and dentists in the early stages of their career. Readers will find detailed information on the epidemiology of individual diseases and disorders and on hot topics and methods in oral health research. The extensive first part of the book explores the international epidemiological literature regarding a wide range of conditions, from dental caries and periodontal diseases to halitosis and malocclusions. In each case, the prevalence, disease-specific measures, and associated factors are identified. Attention is then focused on cutting-edge research topics in oral epidemiology, such as the intriguing mechanisms linking oral diseases and chronic general diseases, life course epidemiology, and the role of socioeconomic determinants of oral health. The final part of the book is devoted to description of the epidemiological methods and tools applied in the field of oral health. Here, the coverage includes validation of questionnaires, data collection and data analyses, and systematic reviews and meta-analyses.

Genomics of Pain and Co-Morbid Symptoms

Genomics of Pain and Co-Morbid Symptoms PDF Author: Susan G. Dorsey
Publisher: Springer Nature
ISBN: 3030216578
Category : Medical
Languages : en
Pages : 254

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Book Description
This book provides an overview of the field of pain genomics and the genomics of related, or co-occuring, symptoms, the current state-of-the-science, and challenges that remain. It brings differing views in the field together and provides examples of translational science from using cellular and rodent models to human clinical trials. This book's structure leads the reader through the physiology of pain and genomics into how pain is studied, mechanisms of acute and chronic pain, various protocols that are used throughout the field along with the pros/cons of the current methods used, and project into the future of pain genomics. This work is intended for classroom teaching, for nurses, for novice researchers in symptom science and pain research as well as students and postdoctoral fellows.