Organoselenium Compounds in Biology and Medicine

Organoselenium Compounds in Biology and Medicine PDF Author: Vimal Kumar Jain
Publisher: Royal Society of Chemistry
ISBN: 1788010299
Category : Organoselenium compounds
Languages : en
Pages : 457

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Book Description
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.

Organoselenium Compounds in Biology and Medicine

Organoselenium Compounds in Biology and Medicine PDF Author: Vimal Kumar Jain
Publisher: Royal Society of Chemistry
ISBN: 1788010299
Category : Organoselenium compounds
Languages : en
Pages : 457

Get Book

Book Description
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.

Selenium in Biology and Medicine

Selenium in Biology and Medicine PDF Author: Albrecht Wendel
Publisher: Springer Science & Business Media
ISBN: 3642744214
Category : Science
Languages : en
Pages : 339

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Book Description
In July, 1988, more than 300 scientists from 29 different countries gathered at Tiibingen, W. Germany, in order to spend 4 days discussing their favourite trace element, selenium. This meeting continued the good tradition of three previous meetings held in Corvallis/Oregon, 1976, in Lubbock/Texas, 1980, and in Beijing/China, in 1984. Incidentally, the University of Tiibingen provided a unique historical background for a Symposium devoted to recent advances in biochemistry, pharmacology, human nutrition and human health; here, the first independent depart ment of Physiological Chemistry in Germany was founded in 1845. Pro fessor H9Ppe-Seyler elucidated here the hemin structure and his student Friedrich Miescher discovered the nucleic acids. This book contains one-half of the oral or poster presentations which were selected before the meeting was held on the basis of a one page abstract. It is the reader who will have to decide whether this time consuming policy of quality assessment was warranted or not.

Organoselenium Compounds in Biology and Medicine

Organoselenium Compounds in Biology and Medicine PDF Author: Vimal Kumar Jain
Publisher: Royal Society of Chemistry
ISBN: 1788012232
Category : Science
Languages : en
Pages : 476

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Book Description
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.

New Frontiers in Organoselenium Compounds

New Frontiers in Organoselenium Compounds PDF Author: Eder João Lenardão
Publisher: Springer
ISBN: 3319924052
Category : Science
Languages : en
Pages : 189

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Book Description
This book presents recent advances in and perspectives on the use of organoselenium compounds, primarily highlighting the new frontiers in the field of Green Chemistry, their therapeutic and biological relevance and new materials. Throughout its 200 pages, readers will find an updated and comprehensive review of new aspects of organoselenium chemistry and biochemistry. Fully referenced and written in an easy to read style, it offers readers a primary resource for including organoselenium derivatives in their projects. This book will be of interest to specialists, students and researchers involved in a broad range of fields, from synthetic green chemistry to medicinal chemistry and the chemistry of natural products. The connection between organoselenium compounds and green chemistry, despite having only recently emerged, is one of the subjects of this book. The first chapter highlights the use of Se-containing molecules as reagents and catalysts in new green protocols to access important organic transformations. The book provides a wealth of examples of bioactive Se-containing molecules, especially focusing on those with potential therapeutic uses. The second chapter focuses on the state of the art concerning the role of organoselenium compounds as antioxidants, GPx mimics, and derivatives endowed with different bioactive properties. “Organoselenium in nature” is the title of the third chapter, which equips readers with essential information on the main natural organoselenium compounds and where they are found. Selected aspects of the metabolism of selenium in plants and microorganisms are also discussed. In closing, the book includes a chapter dedicated to recent advances concerning the nonbonding interactions between organochalcogen compounds. This is currently a hot topic in selenium chemistry and biochemistry, and here readers will find key insights into the chalcogen bond and its role in the biological activity of organoselenium compounds.

Selenium in biology and medicine

Selenium in biology and medicine PDF Author: Albrecht Wendel
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description


Selenium in Biology and Medicine

Selenium in Biology and Medicine PDF Author: Albrecht Wendel
Publisher:
ISBN: 9783642744228
Category :
Languages : en
Pages : 352

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Book Description
The book gives an account of the most recent development in the understanding of the essential trace element selenium with respect to its role in animals and man. It is divided into five sections covering biochemistry, metabolism, pharmacology, human nutrition and epidemiology, and the interaction of selenium with malignant diseases. Primary new information is available on the synthesis of selenoproteins, metabolic selenium-dependent modulations in animals, and brand-new results on the development of a new, selenium-containing anti-inflammatory drug. For the first time, data from China are presented on the chronic toxicity of selenium in man. A critical appraisal of the debate on the anticarcinogenic effect of selenium is given. Recommended daily intakes of selenium for man and epidemiological data on different countries of the world are reported.

Organoselenium Chemistry

Organoselenium Chemistry PDF Author: Brindaban C. Ranu
Publisher: de Gruyter
ISBN: 9783110622249
Category : Science
Languages : en
Pages : 0

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Book Description
"Selenium plays an important role in the operation of biological processes. Thus, organoselenium compounds are of current interest in chemistry as well as in biology. This book covers a wide section of selenium chemistry. It provides an overview of the synthesis of a variety of organoselenides including selenourea, selenocarbonyls, selenoamides, selenazadienes and Se-containing heterocycles by various approaches such as coupling, C-H activation, radical reactions, and microwave induced reactions. The applications of selenides in biological processes, pharmacology and as reagents and catalysts have been illustrated"--Page 4 of cover.

Organoselenium Chemistry Between Synthesis and Biochemistry

Organoselenium Chemistry Between Synthesis and Biochemistry PDF Author: Claudio Santi
Publisher: Bentham Science Publishers
ISBN: 1608058387
Category : Science
Languages : en
Pages : 442

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Book Description
The use of organoselenium reagents as catalysts is a common thread that runs through the chapters of this book, introducing important aspects of the modern organoselenium chemistry: organocatalysis, green chemistry, bioinspiration, antioxidant activity. The eBook covers the most recent developments in the classical synthetic application of organoselenium reagents such as electrophilic, nucleophilic and free radical reagents. The volume also features a discussion on the synthesis and the synthetic applications of some emerging classes of selenium compounds such as hypervalent selenium species and selenoamides, and also addresses some biological aspects such as the antimicrobial activity of organoselenium derivatives and the biochemistry of selenoproteins. A number of eminent scientists from different research groups were involved in the preparation of the 13 chapters of the book, making Organoselenium Chemistry: Between Synthesis and Biochemistry an excellent reference about selenium chemistry for researchers and graduate students in the field of selenium chemistry.

Organochalcogen Compounds

Organochalcogen Compounds PDF Author: Eder João Lenardão
Publisher: Elsevier
ISBN: 0128194502
Category : Science
Languages : en
Pages : 341

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Book Description
Organochalcogen compounds reviews the state of the art in new green protocols involving organochalcogen compounds (Se, S, and Te), including the use of nonconventional reaction media, alternative solvents, and solvent-free protocols to prepare these important compounds. Bringing together several leading researchers in organochalcogen chemistry, it provides an authoritative overview of the current state of the field and compiles recent advances in methodologies for the application of green chemistry principles in compound development. These include the use of organochalcogen compounds as intermediates, catalysts, or target products across a range of applications. The recent developments outlined in in the book reflect the efforts of the researchers in this area to move toward a more sustainable chemistry, giving the book the dual benefit of highlighting the latest developments in the field while also showing how the principles of green chemistry can effectively be included in active research projects. Thus it is a valuable reference for chemists, particularly those working in organic, green, and synthetic chemistry across both academia and industry. Highlights green synthetic methods with potential application in the synthesis of natural compounds or other biologically active scaffolds Explores the chemical modification of natural compounds by insertion of organochalcogen groups for the preparation of boosted bioactive semisynthetic molecules Discuss how redox catalysis and catalysis in flow conditions using eco-friendly oxidant can provide new opportunities for the synthesis of linear ad cyclic derivatives

Selenium

Selenium PDF Author: Victor R. Preedy
Publisher: Royal Society of Chemistry
ISBN: 1849738912
Category : Medical
Languages : en
Pages : 666

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Book Description
Although toxic in large doses, selenium is an essential trace mineral in the animal diet and in some plants. It has a role in making antioxidant enzymes and a particular role in the functioning of the thyroid gland. This volume examines the chemical activity of selenium and its functional health effects eg towards cancers, in the heart and brain. It also covers other areas such as functional food enrichment, whole body metabolism, and the effects of selenium deficiency on health. Part of The Food and Nutritional Components in Focus series, this edited volume pools knowledge across scientific disciplines in a way that increases its applicability to a wide range of audiences. Victor Preedy’s own distinguished career in nutritional science has made him a prolific author of research articles and books in this area, and this project fills a gap in providing comprehensive synopses of food substances. Chemists, analytical scientists, forensic scientists, food scientists, as well as course lecturers will all benefit from this interdisciplinary title written by international experts in this area.