Organophosphates, Friend and Foe

Organophosphates, Friend and Foe PDF Author: Adriane Busby
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Get Book Here

Book Description
Millions of farm workers nation-wide who load, mix and/or apply pesticides are exposed to incredible amounts of pesticides on a daily basis. Various inefficiencies and inconsistencies in the regulatory system - including insufficient illness reporting data systems, lack of regulatory compliance and enforcement, and inadequate data and information on the chronic effects of exposure and overexposure to various pesticides - increase the likelihood that these workers will continue to be exposed to dangerous amounts of pesticides. This Article assesses the existing mechanisms designed to protect farm workers from occupational exposure to pesticides and identifies and analyzes some of the shortcomings of the regulatory system. It focuses on the class of pesticides known as organophosphates and examines the impact that such pesticides can have on farm workers as well as on their families. It then evaluates the State of Washington's medical monitoring rule, and recommends implementation of a federal medical monitoring program as a means of protecting all American farm workers from the dangers of pesticide overexposure.

Organophosphates, Friend and Foe

Organophosphates, Friend and Foe PDF Author: Adriane Busby
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Get Book Here

Book Description
Millions of farm workers nation-wide who load, mix and/or apply pesticides are exposed to incredible amounts of pesticides on a daily basis. Various inefficiencies and inconsistencies in the regulatory system - including insufficient illness reporting data systems, lack of regulatory compliance and enforcement, and inadequate data and information on the chronic effects of exposure and overexposure to various pesticides - increase the likelihood that these workers will continue to be exposed to dangerous amounts of pesticides. This Article assesses the existing mechanisms designed to protect farm workers from occupational exposure to pesticides and identifies and analyzes some of the shortcomings of the regulatory system. It focuses on the class of pesticides known as organophosphates and examines the impact that such pesticides can have on farm workers as well as on their families. It then evaluates the State of Washington's medical monitoring rule, and recommends implementation of a federal medical monitoring program as a means of protecting all American farm workers from the dangers of pesticide overexposure.

Toxicology of Organophosphate and Carbamate Compounds

Toxicology of Organophosphate and Carbamate Compounds PDF Author: Ramesh C Gupta
Publisher: Academic Press
ISBN: 0080543103
Category : Technology & Engineering
Languages : en
Pages : 781

Get Book Here

Book Description
This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. - Describes everything you need to know about Organophosphates and Carbamates - Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants - Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates - Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases - Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity - Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis - Provides in vitro and in vivo models for neurotoxicity testing - Integrates knowledge of studies in lab animals and humans - Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues - Describes management of Anticholinesterase poisoning in humans

Abatement of Environmental Pollutants

Abatement of Environmental Pollutants PDF Author: Pardeep Singh
Publisher: Elsevier
ISBN: 012818096X
Category : Science
Languages : en
Pages : 380

Get Book Here

Book Description
Abatement of Environmental Pollutants: Trends and Strategies addresses new technologies and provides strategies for environmental scientists, microbiologists and biotechnologists to help solve problems associated with the treatment of industrial wastewater. The book helps readers solve pollution challenges using microorganisms in bioremediation technologies, including discussions on global technologies that have been adopted for the treatment of industrial wastewater and sections on the lack of proper management. Moreover, limited space, more stringent waste disposal regulations and public consciousness have made the present techniques expensive and impractical. Therefore, there is an urgent need to develop sustainable management technologies for industries and municipalities. To remove the damaging effect of organic pollutants on the environment, various new technologies for their degradation have been recently discovered. - Covers bioremediation of petrochemical pollutants, such as Benzene, Toluene, Xylene, Ethyl Benzene, and phenolic compound - Includes discussions on genetic engineering microbes and their potential in pollution abatement - Contains information on plant growth promoting bacteria and their role in environment management

Biology of Composts

Biology of Composts PDF Author: Mukesh K. Meghvansi
Publisher: Springer Nature
ISBN: 3030391736
Category : Science
Languages : en
Pages : 297

Get Book Here

Book Description
This book highlights the latest findings on fundamental aspects of composting, the interaction of various microorganisms, and the underlying mechanisms. In addition to addressing modern tools and techniques used for composting research, it provides an overview of potential composting applications in both agriculture and environmental reclamation. Composting is the process of organic waste decomposition, mediated by microorganisms. The end-product is called ‘compost’ and can be used as a supplement to improve soil fertility. As the municipal waste generated in most developing countries contains a substantial amount of organic matter suitable for composting, this technology offers a win-win opportunity for stakeholders in terms of disposing of organic waste and providing organic fertilizers for agriculture. In addition, using compost reduces the dependency on harmful chemical fertilizers, and represents a sustainable and environmentally friendly alternative.

The Irritable Heart

The Irritable Heart PDF Author: Jeff Wheelwright
Publisher: W. W. Norton & Company
ISBN: 9780393019568
Category : Case studies
Languages : en
Pages : 444

Get Book Here

Book Description
Wheelwright (former science editor for Life magazine) profiles five ailing Gulf War veterans from their deployment to the Gulf, through their experiences in the Gulf War, and their subsequent illnesses and attempts to discover the causes. He argues that the illnesses belong in the company of chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivity. Pointing out precedents in military history that go back as far as a Civil War malady known as "irritable heart," he argues that the illnesses are a combination of physical symptoms greatly magnified by psychological distress. Because modern medicine deals with the body and mind separately, he contends, the health investigation of the veteran's illnesses is bound to fail. Annotation copyrighted by Book News Inc., Portland, OR

Insecticide Biochemistry and Physiology

Insecticide Biochemistry and Physiology PDF Author: Christopher Foster Wilkinson
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 796

Get Book Here

Book Description
Only four short decades ago, the control of insect pests by means of chemicals was in its early infancy. The pioneers in the area consisted largely of a group of dedicated applied entomologists working to the best of their abilities with a very limited arsenal of chemicals that included inorganics (arsenicals, fluorides, etc.), some botanicals (nicotine), and a few synthetic organics (dinitro-o-cresol, organothiocyanates). Much of the early research was devoted to solving practical problems associated with the formulation and application of the few existing materials, and although the discovery of new types of insecticidal chemicals was undoubtedly a pipe dream in the minds of some, little or no basic research effort was expended in this direction. The discovery of the insecticidal properties of DDT by Paul Miiller in 1939 has to be viewed as the event which marked the birth of modern insecticide chemistry and which has served as the cornerstone for its subse quent developement. DDT clearly demonstrated for the first time the dramatic potential of synthetic organic chemicals for insect control and provided the initial stimulus which has caused insecticide chemistry to become a field not only of immense agricultural and public health importance but also one that has had remarkable and unforseeable repercussions in broad areas of the physical, biological, and social sciences. Indeed, there can be few other synthetic chemicals which will be judged in history to have had such a broad and telling impact on mankind as has DDT.

The HDL Handbook

The HDL Handbook PDF Author: Tsugikazu Komoda
Publisher: Academic Press
ISBN: 0124079245
Category : Medical
Languages : en
Pages : 355

Get Book Here

Book Description
The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol. - Provides bench-to-bedside coverage of HDL with thorough coverage of basic science, genetics, epidemiology, and treatment - Presents a complete update with six new chapters on the latest advances in HDL cholesterol research with international perspective - New chapters on proteomics, clinical impact of LCAT in HDL metabolism, and an in-depth discussion of potential targets to modify HDL provide a translational reference for clinicians

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure PDF Author: Aristidis M. Tsatsakis
Publisher: Elsevier
ISBN: 0323853587
Category : Medical
Languages : en
Pages : 684

Get Book Here

Book Description
Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. • Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field • Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease • Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research

Selectivity and Efficacy of Sulfonylurea Herbicides and Wild-proso Millet Competition in Field and Sweet Corn

Selectivity and Efficacy of Sulfonylurea Herbicides and Wild-proso Millet Competition in Field and Sweet Corn PDF Author: Cathy A. Morton
Publisher:
ISBN:
Category :
Languages : en
Pages : 352

Get Book Here

Book Description


Mechanisms of Epithelial Defense

Mechanisms of Epithelial Defense PDF Author: Dieter Kabelitz
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805578628
Category : Medical
Languages : en
Pages : 203

Get Book Here

Book Description
Annotation Epithelial defense against infectious agents relies on the recognition of microbial products by pattern recognition receptors and the local production of antimicrobial peptides. This book provides a state-of-the-art overview of the basic characteristics and clinical relevance of antimicrobial peptides, with special emphasis on their role in skin, intestinal and lung inflammation. The evolutionary significance of antimicrobial peptides is highlighted by an in-depth analysis of their structure, activity and gene regulation in Drosophila melanogaster. Toll-like receptors are an important class of pattern recognition receptors, whose roles in recognizing bacterial molecular patterns and in the intracellular signalling pathways involved in the differentiation and function of dendritic cells are discussed. Finally, this book also addresses the role of intraepithelial lympho cytes in epithelial defense, notably of T cells which form a link between innate and adaptive immune responses. The combined analysis of epithelial and lymphoid cells and effector mechanisms sheds new light on the epithelial defense system in physiological and pathophysiological conditions. Immunologists, dermatologists, microbiologists, and infectious disease specialists will greatly benefit from the wealth of new findings presented by leading investigators.