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Author: Carlos Guido Musso
Publisher: Springer Nature
ISBN: 3031367898
Category : Medical
Languages : en
Pages : 219
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Book Description
This is an original work dedicated to an important and current topic in nephrology: organ crosstalk in acute renal injury. Acute kidney injury is a prevalent and serious syndrome. The related mortality to this syndrome has not been significantly reduced in the last decades despite the advances in renal replacement therapy technology. For this reason, a new approach to obtain an effective treatment is urgently needed. The organ crosstalk perspective could be useful in order to achieve this objective since it implies a very early acute kidney injury diagnose and treatment. This book includes a comprehensive review of the organ crosstalk perspective in acute kidney injury. Organized in two parts, the chapters in the first part present general subjects as an introduction to analysing the crosstalk concept. These chapters give an overview of the concepts of biosemiotics, hormones, neurotransmitters, cytokines, signalling and adhesion molecules, organ intercommunication, and epigenetics. The second part gathers chapters on the different kidney crosstalk, such as brain, lung, heart, liver, gut, and placenta. Finally, there is a chapter dedicated to the influence of renal replacement treatment on kidney crosstalk. Since acute kidney injury is a topic of interest to many health professionals, this work will be a useful resource to general practitioners, internal medicine physicians, geriatricians, nephrologists, critical care therapists, immunologists, and also biologists and bioengineers.
Author: Carlos Guido Musso
Publisher: Springer Nature
ISBN: 3031367898
Category : Medical
Languages : en
Pages : 219
Get Book Here
Book Description
This is an original work dedicated to an important and current topic in nephrology: organ crosstalk in acute renal injury. Acute kidney injury is a prevalent and serious syndrome. The related mortality to this syndrome has not been significantly reduced in the last decades despite the advances in renal replacement therapy technology. For this reason, a new approach to obtain an effective treatment is urgently needed. The organ crosstalk perspective could be useful in order to achieve this objective since it implies a very early acute kidney injury diagnose and treatment. This book includes a comprehensive review of the organ crosstalk perspective in acute kidney injury. Organized in two parts, the chapters in the first part present general subjects as an introduction to analysing the crosstalk concept. These chapters give an overview of the concepts of biosemiotics, hormones, neurotransmitters, cytokines, signalling and adhesion molecules, organ intercommunication, and epigenetics. The second part gathers chapters on the different kidney crosstalk, such as brain, lung, heart, liver, gut, and placenta. Finally, there is a chapter dedicated to the influence of renal replacement treatment on kidney crosstalk. Since acute kidney injury is a topic of interest to many health professionals, this work will be a useful resource to general practitioners, internal medicine physicians, geriatricians, nephrologists, critical care therapists, immunologists, and also biologists and bioengineers.
Author: Derek S. Wheeler
Publisher: Springer Science & Business Media
ISBN: 9781846284632
Category : Medical
Languages : en
Pages : 1854
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Book Description
This new textbook is the definitive evidence-based resource for pediatric critical care. It is the first ostensibly evidence-based pediatric critical care textbook and will prove an invaluable resource for critical care professionals across the globe.
Author: Peter A. McCullough
Publisher: Springer Nature
ISBN: 3030574601
Category : Medical
Languages : en
Pages : 381
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Book Description
This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings together experts at the nexus between cardiovascular and renal medicine to provide an exception reference to educate in this critical area of modern medicine. It describes how the heart and kidneys are inextricably linked via hemodynamic, neural, hormonal and cellular signaling systems and, concentrating on disease-based coverage, goes on to review emerging concepts in epidemiology, pathogenesis, screening, diagnosis and the management of cardiorenal syndromes, all extensively illustrated and containing features to support scholarship in the field. Textbook of Cardiorenal Medicine provides consistent chapter organization, clear design and engaging text to define the diagnosis, treatment, intervention and surgical aspects of the full range of conditions encountered within this area of medicine. It is therefore an essential resource to all involved in the management of cardiorenal disease.
Author: Yoshio Terada
Publisher: Springer Nature
ISBN: 981151108X
Category : Medical
Languages : en
Pages : 390
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Book Description
This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.
Author: Neil N. Turner
Publisher: Oxford University Press
ISBN: 0191017655
Category : Medical
Languages : en
Pages : 3045
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Book Description
This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.
Author: Hiromichi Suzuki
Publisher: Karger Medical and Scientific Publishers
ISBN: 380559478X
Category : Medical
Languages : en
Pages : 204
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Book Description
Acute organ damage and the ensuing multiple organ failure are the result of a pathophysiological process involving various cytokines. Once activated, these proteins cannot be eliminated even when the kidneys function at their maximum capacity. To counteract this mechanism, researchers in Japan have developed an innovative concept employing blood purification to remove the overwhelming cytokines. This book describes the use of hemodiafiltration to inhibit the cytokine storms which cause serious organ damage in patients with septic shock. Moreover, the technical construction of the blood purification system, which includes various machines, devices, membranes, fluids, etc., is explained in detail. Finally, leading experts discuss the concept of continuous renal replacement therapy as the standard care in critically ill patients with severe acute kidney injury. Describing the current state of acute blood purification, this publication provides new impulses and opens new avenues in the treatment of acute organ damage.
Author: Stefano Govoni
Publisher: Springer
ISBN: 9783030280079
Category : Medical
Languages : en
Pages : 0
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Book Description
This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the core topic: from social and philosophical to gender-related aspects. It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.
Author: Heleen M. Oudemans-van Straaten
Publisher: Springer
ISBN: 3319173898
Category : Medical
Languages : en
Pages : 280
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Book Description
This practical guide provides the reader with answers to important clinically relevant questions regarding the evaluation and management of acute kidney injury (AKI). All aspects of critical care nephrology are covered, from pathophysiology and diagnosis to prevention and treatment. The questions considered relate to a wide range of issues, such as: How do I diagnose AKI? How can I protect the kidney in clinical practice? How do I manage patients with AKI? When should I initiate and how do I perform renal replacement therapy (RTT)? Which type of RTT is most appropriate for my patient? Should I give specific nutrients? In addition to providing practical guidelines and treatment algorithms, the book includes calculators for continuous RRT and anticoagulant dosing. The authors are internationally renowned experts in the fields of Intensive Care Medicine and Nephrology and all contributions are written in a clear and concise style and have been peer reviewed. Acute Nephrology for the Critical Care Physician will serve as a very useful source for intensivist internists, anesthesiologists and nephrologists involved in the management and treatment of critically ill patients at risk of or affected by AKI.
Author: Sushrut S. Waikar
Publisher: Springer
ISBN: 9781493986262
Category : Medical
Languages : en
Pages : 0
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Book Description
This comprehensive guide covers the causes, characteristics, and presentations of acute kidney injury (AKI), as well as prevention and treatment. The first part of the book features chapters on the epidemiology and diagnosis of AKI. This is followed by sections on pathophysiology, clinical syndromes and patient management. Authored by leading clinicians, epidemiologists, basic scientists, and clinical trialists, this book captures the latest evidence and best practices for treating patients with AKI.
Author: R. Bellomo
Publisher: Karger Medical and Scientific Publishers
ISBN: 331806307X
Category : Medical
Languages : en
Pages : 184
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Book Description
Continuous renal replacement therapies (CRRT) started off as an alternative to hemo- or peritoneal dialysis. Today's machines and techniques are the result of 4 decades of developments, studies, and practices which can be divided into 4 distinct stages: exploration and development; birth of a new specialty called critical care nephrology; design of specific new devices and machines; and interaction among various specialists to adapt extracorporeal therapies for multiple organ support and sepsis. This book features contributions from prominent CRRT experts from around the world. It is an important tool for educating a new generation of nephrologists and intensivists. At the same time, it provides the most advanced CRRT users with the latest technological information, the most updated clinical evidence, and the personal opinion of key leaders who contributed to the last 40 years of history in the field.
