Of Mice, Models, and Men

Of Mice, Models, and Men PDF Author: Andrew N. Rowan
Publisher: SUNY Press
ISBN: 9780873957762
Category : Nature
Languages : en
Pages : 346

Get Book Here

Book Description
Too much emotion and insufficient fact. This paradox has long characterized the controversy surrounding animal research. Of Mice, Models, and Men is the first exhaustive treatment of all areas--empirical and conceptual--relevant to the use of animals in research. It is also the first study to combine regard for the welfare of laboratory animals with a knowledgeable acceptance of the continuing need for research involving animals. The book has another rare quality. It is virtually devoid of any of the emotional and exaggerated attacks that have characterized many of the other publications in this area. Instead, it presents, in a manner accessible to both sides, all the relevant historical, social, and scientific information required to form an opinion on the subject. The book thus achieves a most difficult goal--that of bridging the gap between researchers using animals and animal welfare advocates, while pointing out the need for a more active program to promote laboratory animal welfare.

Of Flies, Mice, and Men

Of Flies, Mice, and Men PDF Author: François Jacob
Publisher: Harvard University Press
ISBN: 9780674631113
Category : Science
Languages : en
Pages : 178

Get Book Here

Book Description
"Tells the story of how the marvelous discoveries of molecular and developmental biology are transforming our understanding of who we are and where we came from. Jacob scrutinizes the place of the scientist in society". -- Jacket.

Genetics of Human Infertility

Genetics of Human Infertility PDF Author: P.H. Vogt
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318060984
Category : Medical
Languages : en
Pages : 190

Get Book Here

Book Description
Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.

Of Mice, Models, and Men

Of Mice, Models, and Men PDF Author: Andrew N. Rowan
Publisher: State University of New York Press
ISBN: 1438418116
Category : Social Science
Languages : en
Pages : 344

Get Book Here

Book Description
Too much emotion and insufficient fact. This paradox has long characterized the controversy surrounding animal research. Of Mice, Models, and Men is the first exhaustive treatment of all areas—empirical and conceptual—relevant to the use of animals in research. It is also the first study to combine regard for the welfare of laboratory animals with a knowledgeable acceptance of the continuing need for research involving animals. The book has another rare quality. It is virtually devoid of any of the emotional and exaggerated attacks that have characterized many of the other publications in this area. Instead, it presents, in a manner accessible to both sides, all the relevant historical, social, and scientific information required to form an opinion on the subject. The book thus achieves a most difficult goal—that of bridging the gap between researchers using animals and animal welfare advocates, while pointing out the need for a more active program to promote laboratory animal welfare.

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309154006
Category : Science
Languages : en
Pages : 246

Get Book Here

Book Description
A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

A Guide to the Scientific Career

A Guide to the Scientific Career PDF Author: Mohammadali M. Shoja
Publisher: John Wiley & Sons
ISBN: 1118907426
Category : Science
Languages : en
Pages : 786

Get Book Here

Book Description
A concise, easy-to-read source of essential tips and skills for writing research papers and career management In order to be truly successful in the biomedical professions, one must have excellent communication skills and networking abilities. Of equal importance is the possession of sufficient clinical knowledge, as well as a proficiency in conducting research and writing scientific papers. This unique and important book provides medical students and residents with the most commonly encountered topics in the academic and professional lifestyle, teaching them all of the practical nuances that are often only learned through experience. Written by a team of experienced professionals to help guide younger researchers, A Guide to the Scientific Career: Virtues, Communication, Research and Academic Writing features ten sections composed of seventy-four chapters that cover: qualities of research scientists; career satisfaction and its determinants; publishing in academic medicine; assessing a researcher’s scientific productivity and scholarly impact; manners in academics; communication skills; essence of collaborative research; dealing with manipulative people; writing and scientific misconduct: ethical and legal aspects; plagiarism; research regulations, proposals, grants, and practice; publication and resources; tips on writing every type of paper and report; and much more. An easy-to-read source of essential tips and skills for scientific research Emphasizes good communication skills, sound clinical judgment, knowledge of research methodology, and good writing skills Offers comprehensive guidelines that address every aspect of the medical student/resident academic and professional lifestyle Combines elements of a career-management guide and publication guide in one comprehensive reference source Includes selected personal stories by great researchers, fascinating writers, inspiring mentors, and extraordinary clinicians/scientists A Guide to the Scientific Career: Virtues, Communication, Research and Academic Writing is an excellent interdisciplinary text that will appeal to all medical students and scientists who seek to improve their writing and communication skills in order to make the most of their chosen career.

World as Laboratory

World as Laboratory PDF Author: Rebecca Lemov
Publisher: Macmillan + ORM
ISBN: 0374707294
Category : Science
Languages : en
Pages : 378

Get Book Here

Book Description
Deeply researched, World as Laboratory tells a secret history that's not really a secret. The fruits of human engineering are all around us: advertising, polls, focus groups, the ubiquitous habit of "spin" practiced by marketers and politicians. What Rebecca Lemov cleverly traces for the first time is how the absurd, the practical, and the dangerous experiments of the human engineers of the first half of the twentieth century left their laboratories to become our day-to-day reality.

ILAR News

ILAR News PDF Author:
Publisher:
ISBN:
Category : Laboratory animals
Languages : en
Pages : 504

Get Book Here

Book Description


Of Mice and Men

Of Mice and Men PDF Author: John Steinbeck
Publisher: Lulu.com
ISBN: 0359199143
Category : Self-Help
Languages : en
Pages : 106

Get Book Here

Book Description
Of Mice and Men es una novela escrita por el autor John Steinbeck. Publicado en 1937, cuenta la historia de George Milton y Lennie Small, dos trabajadores desplazados del rancho migratorio, que se mudan de un lugar a otro en California en busca de nuevas oportunidades de trabajo durante la Gran Depresión en los Estados Unidos.

Studies on Men's Health and Fertility

Studies on Men's Health and Fertility PDF Author: Ashok Agarwal
Publisher: Springer Science & Business Media
ISBN: 1617797766
Category : Science
Languages : en
Pages : 671

Get Book Here

Book Description
Studies on Men’s Health and Fertility provides a comprehensive series of up-to-the-minute reviews addressing the role of oxidative stress in the aetiology of reproductive pathologies in the male. This volume represents by far the most detailed, authoritative review of the field that has been produced to date. The text encompasses the basic science of reactive oxygen species (ROS) production by mammalian spermatozoa, the way in which these highly reactive molecules are processed by the germ line and the physiological significance of this redox activity in the generation of a functional gamete. The factors responsible for perturbing the delicate balance between physiological redox signaling on the one hand and oxidative stress on the other are also extensively reviewed and some of the first clues concerning the underlying mechanisms (age, heat, infection, cryostorage, aberrant lipid metabolism), clearly identified. From a clinical perspective there are chapters setting out the methods we should be using to diagnose oxidative stress in the male germ line, a clinical perspective on the aetiology of this condition and detailed considerations of the most suitable means of ameliorating such stress from a therapeutic point of view. Studies on Men’s Health and Fertility is intended to provide clinicians and scientists with a snap shot of the current status of this exciting, rapidly moving field. The book will be of value to clinicians interested in strategies for the management of oxidative stress in their infertility patients and scientists wishing to understand the molecular mechanisms underpinning the generation of ROS by these cells and its pathophysiological significance. It was not so long ago that the ability of spermatozoa to generate ROS was a hotly disputed topic. With the publication of this book such doubts can finally be laid to rest. There is now no doubt that these cells actively generate ROS, that oxidative stress is a major contributor to defects in male reproductive health and that the successful clinical management of this condition depends on developing a deeper understanding of the underlying molecular mechanisms. In this quest, Studies on Men’s Health and Fertility will be seen as a clear and important milestone.