OECD Series on Testing and Assessment Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download OECD Series on Testing and Assessment Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors PDF full book. Access full book title OECD Series on Testing and Assessment Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors by OECD. Download full books in PDF and EPUB format.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264085491
Category :
Languages : en
Pages : 95
Get Book
Book Description
This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264085491
Category :
Languages : en
Pages : 95
Get Book
Book Description
This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264221352
Category :
Languages : en
Pages : 213
Get Book
Book Description
This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs).
Author: OECD
Publisher: OECD Publishing
ISBN: 9264079157
Category :
Languages : en
Pages : 170
Get Book
Book Description
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264274715
Category :
Languages : en
Pages : 148
Get Book
Book Description
This scoping document aims at bringing forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, to provide recommendations for their development/use, and also, to identify aspects/blocks of the thyroid signalling pathways that are not covered and would ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264221468
Category :
Languages : en
Pages : 182
Get Book
Book Description
This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264304746
Category :
Languages : en
Pages : 692
Get Book
Book Description
This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264304797
Category :
Languages : en
Pages : 206
Get Book
Book Description
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264221417
Category :
Languages : en
Pages : 524
Get Book
Book Description
This document is a tool to support regulatory authorities’ decisions on the hazard of specific chemicals when they receive test results from a Test Guideline (TG) or draft TG for the screening/testing of chemicals for endocrine disrupting properties.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264221441
Category :
Languages : en
Pages : 105
Get Book
Book Description
This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to key events.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264221433
Category :
Languages : en
Pages : 174
Get Book
Book Description
This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant.
