OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264242791
Category :
Languages : en
Pages : 13

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Book Description
This updated Test Guideline 435 provides an in vitro membrane barrier test method that can be used to identify corrosive chemicals. The test method utilizes an artificial membrane designed to respond to corrosive chemicals in a manner similar to animal skin in situ.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264242791
Category :
Languages : en
Pages : 13

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Book Description
This updated Test Guideline 435 provides an in vitro membrane barrier test method that can be used to identify corrosive chemicals. The test method utilizes an artificial membrane designed to respond to corrosive chemicals in a manner similar to animal skin in situ.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 431: In vitro skin corrosion: reconstructed human epidermis (RHE) test method

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 431: In vitro skin corrosion: reconstructed human epidermis (RHE) test method PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264264612
Category :
Languages : en
Pages : 29

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Book Description
The test described in this Test Guideline allows the identification of corrosive chemical substances and mixtures and it enables the identification of non-corrosive substances and mixtures when supported by a weight of evidence determination using other existing information.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER)

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER) PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264242732
Category :
Languages : en
Pages : 15

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Book Description
This Test Guideline addresses the human health endpoint skin corrosion. It is based on the rat skin transcutaneous electrical resistance (TER) test method, which utilizes skin discs to identify corrosives by their ability to produce a loss of normal stratum corneum integrity and barrier function.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 439: In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264242848
Category :
Languages : en
Pages : 28

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Book Description
This Test Guideline describes an in vitro procedure that may be used for the hazard identification of irritant chemicals (substances and mixtures) in accordance with the UN Globally Harmonized System of Classification and Labelling (GHS) Category 2.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264070605
Category :
Languages : en
Pages : 20

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Book Description
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method

OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264076034
Category :
Languages : en
Pages : 27

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Book Description
The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according to the Globally Harmonized System of ...

Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion

Test No. 435: In Vitro Membrane Barrier Test Method for Skin Corrosion PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264067310
Category :
Languages : en
Pages : 15

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Book Description
This Test Guideline is for an in vitro membrane barrier test method that can be used to identify corrosive substances. The test method utilizes an artificial membrane designed to respond to corrosive substances in a manner similar to animal skin in ...

Handbook of Cosmetic Science and Technology

Handbook of Cosmetic Science and Technology PDF Author: Frank Dreher
Publisher: CRC Press
ISBN: 1000590623
Category : Medical
Languages : en
Pages : 997

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Book Description
With chapters from experienced and internationally renowned contributors holding positions in research, industry, and clinical practice, this is the fifth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for the skin. *Offers in-depth analysis of specific topics in cosmetic science and research *Presents the latest in international research and its translation to practice *Gives an indispensable guide to a hotly competitive area for research and practice

Laboratory Animal Welfare

Laboratory Animal Welfare PDF Author: Kathryn Bayne
Publisher: Academic Press
ISBN: 0123851041
Category : Medical
Languages : en
Pages : 335

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Book Description
Laboratory Animal Welfare provides a comprehensive, up-to-date look into the new science of animal welfare within laboratory research. Animals specifically considered include rodents, cats and dogs, nonhuman primates, agricultural animals, avian animals and aquatic animals. The book examines the impact of experiment design and environment on animal welfare, as well as emergency situations and euthanasia practices. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare.

Organotypic Models in Drug Development

Organotypic Models in Drug Development PDF Author: Monika Schäfer-Korting
Publisher: Springer Nature
ISBN: 3030700631
Category : Medical
Languages : en
Pages : 325

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Book Description
This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.