OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319A: Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP) PDF Download
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Author: OECD
Publisher: OECD Publishing
ISBN: 9264303219
Category :
Languages : en
Pages : 41
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Book Description
The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264303219
Category :
Languages : en
Pages : 41
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Book Description
The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9789264303218
Category :
Languages : en
Pages : 0
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Book Description
The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264303235
Category :
Languages : en
Pages : 36
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Book Description
The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: OECD
Publisher: OECD Publishing
ISBN: 9264185291
Category :
Languages : en
Pages : 72
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Book Description
This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264070346
Category :
Languages : en
Pages : 62
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Book Description
This Test Guideline describes six methods that permit the screening of chemicals for ready biodegradability in an aerobic aqueous medium. The methods are: the DOC Die-Away, the CO2 Evolution (Modified Sturm Test), the MITI (I) (Ministry of ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264090932
Category :
Languages : en
Pages : 30
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Book Description
This Test Guideline describes procedures designed to assess bioaccumulation of chemicals in soil oligochaetes. The parameters which characterise the bioaccumulation of a substance include the bioaccumulation factor (BAF), the uptake rate constant ...
Author: OECD
Publisher: OECD Publishing
ISBN: 926406737X
Category :
Languages : en
Pages : 9
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Book Description
This Test Guideline is intended for testing the emissions from wood and wooden commodities that are not covered and are in contact with fresh water or seawater. Preservative treated wood test specimens are immersed in water. The recommended wood ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264070443
Category :
Languages : en
Pages : 11
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Book Description
The method described in this Test Guideline is designed for the evaluation of the mineralisation rate of a 14C-labelled compound in soil. The method is applicable to volatile or non-volatile, soluble or insoluble compounds which are not inhibitory ...
Author: Dennis J. Paustenbach
Publisher: John Wiley & Sons
ISBN: 111974296X
Category : Technology & Engineering
Languages : en
Pages : 1319
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Book Description
Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.
