Author: OECD
Publisher: OECD Publishing
ISBN: 9264015841
Category :
Languages : en
Pages : 17
Book Description
This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ...
OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 123: Partition Coefficient (1-Octanol/Water): Slow-Stirring Method
Author: OECD
Publisher: OECD Publishing
ISBN: 9264015841
Category :
Languages : en
Pages : 17
Book Description
This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ...
Publisher: OECD Publishing
ISBN: 9264015841
Category :
Languages : en
Pages : 17
Book Description
This Test Guideline describes the slow-stirring method, which permits the determination of the 1-octanol/water partition coefficient (POW) values up to a log POW of 8.2. The partition coefficient between water and 1-octanol (POW) is defined as the ...
OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 107: Partition Coefficient (n-octanol/water): Shake Flask Method
Author: OECD
Publisher: OECD Publishing
ISBN: 9264069623
Category :
Languages : en
Pages : 4
Book Description
This Test Guideline describes a method to determine experimentally Pow values in the range log Pow between -2 and 4 (occasionally up to 5). This method can not be used with surface-active materials. The partition coefficient is defined as the ratio ...
Publisher: OECD Publishing
ISBN: 9264069623
Category :
Languages : en
Pages : 4
Book Description
This Test Guideline describes a method to determine experimentally Pow values in the range log Pow between -2 and 4 (occasionally up to 5). This method can not be used with surface-active materials. The partition coefficient is defined as the ratio ...
OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 117: Partition Coefficient (n-octanol/water), HPLC Method
Author: OECD
Publisher: OECD Publishing
ISBN: 9264069828
Category :
Languages : en
Pages : 12
Book Description
This Test Guideline describes the HPLC method, which permits to determine the partition coefficient (n-octanol/water) (Pow). Reverse phase HPLC is performed on analytical columns packed with a solid phase containing long hydrocarbon chains ...
Publisher: OECD Publishing
ISBN: 9264069828
Category :
Languages : en
Pages : 12
Book Description
This Test Guideline describes the HPLC method, which permits to determine the partition coefficient (n-octanol/water) (Pow). Reverse phase HPLC is performed on analytical columns packed with a solid phase containing long hydrocarbon chains ...
OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 120: Solution/Extraction Behaviour of Polymers in Water
Author: OECD
Publisher: OECD Publishing
ISBN: 9264069887
Category :
Languages : en
Pages : 4
Book Description
This Test Guideline describes a method to analyse the solution/extraction behaviour of polymers in water, which uses the flask method with modifications. Three samples of 10 g of particles of the test substance are weighed into each of three vessels ...
Publisher: OECD Publishing
ISBN: 9264069887
Category :
Languages : en
Pages : 4
Book Description
This Test Guideline describes a method to analyse the solution/extraction behaviour of polymers in water, which uses the flask method with modifications. Three samples of 10 g of particles of the test substance are weighed into each of three vessels ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319B: Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub-cellular fraction (RT-S9)
Author: OECD
Publisher: OECD Publishing
ISBN: 9264303235
Category :
Languages : en
Pages : 36
Book Description
The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...
Publisher: OECD Publishing
ISBN: 9264303235
Category :
Languages : en
Pages : 36
Book Description
The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 305: Bioaccumulation in Fish: Aqueous and Dietary Exposure
Author: OECD
Publisher: OECD Publishing
ISBN: 9264185291
Category :
Languages : en
Pages : 72
Book Description
This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...
Publisher: OECD Publishing
ISBN: 9264185291
Category :
Languages : en
Pages : 72
Book Description
This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...
OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 105: Water Solubility
Author: OECD
Publisher: OECD Publishing
ISBN: 9264069585
Category :
Languages : en
Pages : 7
Book Description
This Test Guideline describes methods to determine the water solubility of test substances. The water solubility of a substance is the saturation mass concentration of the substance in water at a given temperature. This guideline addresses the ...
Publisher: OECD Publishing
ISBN: 9264069585
Category :
Languages : en
Pages : 7
Book Description
This Test Guideline describes methods to determine the water solubility of test substances. The water solubility of a substance is the saturation mass concentration of the substance in water at a given temperature. This guideline addresses the ...
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319A: Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP)
Author: OECD
Publisher: OECD Publishing
ISBN: 9264303219
Category :
Languages : en
Pages : 41
Book Description
The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Publisher: OECD Publishing
ISBN: 9264303219
Category :
Languages : en
Pages : 41
Book Description
The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 111: Hydrolysis as a Function of pH
Author: OECD
Publisher: OECD Publishing
ISBN: 9264069704
Category :
Languages : en
Pages : 16
Book Description
This Test Guideline describes a laboratory test method to assess abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 – 9). This Guideline is designed as a tiered approach; each tier ...
Publisher: OECD Publishing
ISBN: 9264069704
Category :
Languages : en
Pages : 16
Book Description
This Test Guideline describes a laboratory test method to assess abiotic hydrolytic transformations of chemicals in aquatic systems at pH values normally found in the environment (pH 4 – 9). This Guideline is designed as a tiered approach; each tier ...
OECD Series on Testing and Assessment Guidance Document on Good In Vitro Method Practices (GIVIMP)
Author: OECD
Publisher: OECD Publishing
ISBN: 9264304797
Category :
Languages : en
Pages : 206
Book Description
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
Publisher: OECD Publishing
ISBN: 9264304797
Category :
Languages : en
Pages : 206
Book Description
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...