OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances PDF Download

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OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264079149
Category :
Languages : en
Pages : 106

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Book Description
This Detailed Review Paper (DRP) provides the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Amphibian Metamorphosis Assay for the Detection of Thyroid Active Substances PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264079149
Category :
Languages : en
Pages : 106

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Book Description
This Detailed Review Paper (DRP) provides the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates.

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 231: Amphibian Metamorphosis Assay

OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 231: Amphibian Metamorphosis Assay PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264076247
Category :
Languages : en
Pages : 33

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Book Description
This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...

OECD Series on Testing and Assessment Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors

OECD Series on Testing and Assessment Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264085491
Category :
Languages : en
Pages : 95

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Book Description
This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Paper on Fish Screening Assays for the Detection of Endocrine Active Substances PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264079157
Category :
Languages : en
Pages : 170

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Book Description
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.

OECD Series on Testing and Assessment Detailed Review Paper (DRP) on Molluscs Life-cycle Toxicity Testing

OECD Series on Testing and Assessment Detailed Review Paper (DRP) on Molluscs Life-cycle Toxicity Testing PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264221468
Category :
Languages : en
Pages : 182

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Book Description
This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals.

OECD Series on Testing and Assessment Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors

OECD Series on Testing and Assessment Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264221352
Category :
Languages : en
Pages : 213

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Book Description
This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs).

OECD Series on Testing and Assessment The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins

OECD Series on Testing and Assessment The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264221441
Category :
Languages : en
Pages : 105

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Book Description
This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to key events.

OECD Series on Testing and Assessment Current Approaches in the Statistical Analysis of Ecotoxicity Data A guidance to application (annexes to this publication exist as a separate document)

OECD Series on Testing and Assessment Current Approaches in the Statistical Analysis of Ecotoxicity Data A guidance to application (annexes to this publication exist as a separate document) PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264085270
Category :
Languages : en
Pages : 147

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Book Description
This document describes the main statistical methods used for analysis of data from ecotoxicological studies .

OECD Series on Testing and Assessment Guidance on Grouping of Chemicals

OECD Series on Testing and Assessment Guidance on Grouping of Chemicals PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264085831
Category :
Languages : en
Pages : 99

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Book Description
This guidance document provides guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely related chemicals as a group, or category, rather than as individual chemicals.

OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals

OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals PDF Author: OECD
Publisher: OECD Publishing
ISBN: 9264221484
Category :
Languages : en
Pages : 118

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Book Description
This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.