Author: Gustavo Pacheco-Lopez
Publisher: Frontiers Media SA
ISBN: 2889713482
Category : Science
Languages : en
Pages : 162

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Book Description

Author: Michael Aschner
Publisher: Academic Press
ISBN: 012800407X
Category : Technology & Engineering
Languages : en
Pages : 451

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Book Description
Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them, such as the effect of diet on attention deficit and hyperactivity disorders. Part Two tackles neurodegenerative disorders, specifically addressing their potential neurotoxic origins, and discussing the increasing interest in the effects that early exposure may have in later life. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders is an invaluable reference for those professionals working in the fields of toxicology, environmental health and neuroscience. Provides, for the first time, the cutting-edge theory of environmental impacts on both neurodegenerative and neurodevelopmental disorders Written by an international selection of the world’s foremost experts in the field of neurotoxicology Full-colour throughout, providing accurate and illustrative examples of neurotoxic effects in action An invaluable reference for those professionals working in the fields of toxicology, environmental health, and neuroscience

Author: Sanjoy Chakraborty
Publisher: CRC Press
ISBN: 1040097189
Category : Health & Fitness
Languages : en
Pages : 623

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Book Description
Obesity is a global pandemic rising beyond the status of a lifestyle disorder, and its consequences include impaired metabolism, energy disruption, and abdominal fat deposition and storage. Body Recomposition: A Comprehensive and Metabolic Alternative to Weight Loss presents information on body recomposition, which emphasizes the approach of losing fat while gaining muscle. It contains vast research on topics including factors that influence fat accumulation, strategies for weight management, healthy diet and eating patterns, physical exercise, and lifestyle strategies in healthy weight management. Features: Influence of non-alcoholic fatty liver disease (NAFLD) on stored fat accumulation and its treatment Harnessing the gut microbial arm in combating obesity Roles of leptin, ghrelin, NPY, cortisol, and diverse neurotransmitters in appetite suppression and regulation Genetic predisposition and genetic addiction obesity risk assessment and therapies Gut–brain axis role in metabolism and body recomposition Efficacy of phytochemicals in weight management and roles of drugs and natural supplements in weight management Importance of physical exercise and manageable lifestyle factors Existing commercial weight loss strategies can fail to achieve and maintain sustainable weight loss or enhance greater healthy fat loss. This book provides an improved alternative for dietitians/nutritionists, health practitioners, and clinicians, as well as food and nutrition scientists.

Author: Eugenio Barone
Publisher: Frontiers Media SA
ISBN: 2889634574
Category : Science
Languages : en
Pages : 157

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Book Description
The failure of insulin signaling – a condition known as insulin resistance – is a key pathological feature of both type 2 diabetes (T2DM, systemic insulin resistance) and Alzheimer’s disease and related dementias (ADRDs, brain insulin resistance) and greatly contribute to their development. Considerable overlap has been identified in the risk factors, comorbidities and putative pathophysiological mechanisms of ADRDs and T2DM, thus proposing AD as type 3 diabetes.

Author: Liliana Letra
Publisher: Springer
ISBN: 3319632604
Category : Medical
Languages : en
Pages : 248

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Book Description
This compendium provides a wide view covering everything from molecular mechanisms and risk factors for neurological disorders to the effects of bariatric surgery on brain function and functional neuroimaging applied to obesity research. The impact of obesity on brain function and the development of neurodegenerative and neuroinflammatory disorders has been understudied, despite the recent proliferation of obesity research. Among the topics covered are adipose biology, the adipose tissue - gut - brain axis, brain energy metabolism, dementia, cerebrovascular disease, and multiple sclerosis.

Author: Peter Gluckman
Publisher: Cambridge University Press
ISBN: 9780521847438
Category : Medical
Languages : en
Pages : 542

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Book Description
This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis has begun to be studied in depth and fully understood. The compilation, written by many of the world's leading experts in this exciting field, summarizes these scientific and clinical advances.

Author: Anna Maria Lavezzi
Publisher: Frontiers Media SA
ISBN: 2832532691
Category : Medical
Languages : en
Pages : 182

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Book Description
Neurodevelopmental disorders are generally influenced by genetic as well as intrauterine and extrauterine factors that affect the fetal-maternal environment and/or brain development that continues after birth. Specific genetic polymorphisms may increase susceptibility to environmental factors that alter the trajectory of brain development via diverse molecular mechanisms. In particular, the pre- and post-natal exposure to neurotoxic metals, pesticides, persistent organic pollutants, and other chemicals is increasingly recognized as involved in the pathogenesis of neurodevelopmental disorders, such as autism, deficiency attention/hyperactivity disorders, neurodegenerative disorders such as Parkinson's and Alzheimer's disease, chronic multiple sclerosis, and even fetal and infant death, including SIUDS (Sudden Unexplained Intrauterine Death Syndrome) and SIDS (Sudden Infant Death Syndrome).

Author:
Publisher: Academic Press
ISBN: 0128155523
Category : Science
Languages : en
Pages : 314

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Book Description
Advances in Neurotoxicology, Volume Two, addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, Mercury and Parkinson’s disease, Pesticides and PD: current evidence, Aluminum and neurodegeneration, Microglia and neurodegeneration, Dietary factors, Mitochondria in neurodegeneration, and Manganese and neurodegeneration. Edited by leading experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. It is an essential resource for researchers and graduate students alike. Includes, in one single publication, a selection of comprehensive reviews devoted to neurotoxicology Edited by high-profile, leading academics in the field, ensuring a quality publication for subscribers Aims to widen the scope for participation by international contributors, researchers and editorial board members outside North America Serves a broad audience of university faculty, researchers and students, as well as the industry, drug development companies and the government

Author: Lorenzo More
Publisher: Frontiers Media SA
ISBN: 2889749827
Category : Science
Languages : en
Pages : 146

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Book Description

Author: John Oloche Onuh
Publisher: CRC Press
ISBN: 1000935876
Category : Medical
Languages : en
Pages : 645

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Book Description
Phytochemicals are receiving increasing attention due to their observed nutritional and health-promoting effects in numerous food applications. As plant secondary metabolites with bioactive properties, they may provide desirable health benefits beyond basic nutrition to reduce chronic disease conditions. Their importance in nutrition and health cannot be overstated as it has generated so much interest and studies focused on elucidating their roles has produced so many outstanding results. Plant phytochemicals are readily used in alternative medicine in South East Asia especially, in China and India and they are becoming widely acceptable worldwide. However, very little is still known about the phytochemicals despite these intense research efforts because of their diverse biological and chemical nature. In this newest addition to the series, Nutraceuticals: Basic Research and Clinical Applications, Plant Food Phytochemicals and Bioactive Compounds in Nutrition and Health provides a comprehensive review of the current state of knowledge in the field of bioactive plant phytochemical compounds, their food sources, bioactivities, bioavailability, extraction, production, and applications. Experts in the field discuss various bioactivities of the notable and promising plant phytochemicals of significance in nutrition and health, e.g., lowering of CVD, hypertension, cholesterol, diabetes, obesity, inflammation, cancer, oxidative stress, neurodegenerative diseases and a host of other chronic disease conditions. Key Features: Describes the various nutritional and bioactive significances of notable and promising plant phytochemicals of significance in nutritional and medical research and their food and/or plant sources Includes various approaches for the quantification, extraction and production of the notable and promising phytochemical compounds in nutrition and health Examines the challenges and promises of plant phytochemical as ingredients for the development of functional foods and nutraceuticals as well as their use in alternative medicine Discusses regulatory issues regarding plant phytochemicals, especially as it pertains to their health claims and use