Numerical Simulation of Airflow and Particle Deposition in Bronchial Airway Bifurcation Models PDF Download
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Author: Thomas Heistracher
Publisher:
ISBN:
Category : Air flow
Languages : en
Pages : 236
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Book Description
Author: Thomas Heistracher
Publisher:
ISBN:
Category : Air flow
Languages : en
Pages : 236
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Book Description
Author: Huawei Shi
Publisher:
ISBN:
Category :
Languages : en
Pages : 187
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Book Description
Keywords: CFD, drug delivery, airflow, particle deposition, nasal airway.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
The human nasal cavities, each with an effective length of only 10cm, feature a wide array of basic flow phenomena due to their complex geometries. Dependent on such airflow fields are the transport and deposition of micro- and nano- particles in the human nasal cavities, of interest to engineers, scientists, air-pollution regulators, and healthcare officials. By utilizing advanced CAD and reverse engineering skills, a realistic model of the human nasal cavity was constructed from MRI image data for 3-D computer simulations. Assuming laminar quasi-steady airflow, dilute micro- and nano-particle suspension flows and local deposition efficiencies were analyzed for 7.5
Author: Chiu-sen Wang
Publisher: Elsevier
ISBN: 0080455018
Category : Technology & Engineering
Languages : en
Pages : 214
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Book Description
Inhaled Particles integrates all that is known about inhaled particles in a unified treatment. It aims to provide a scientific framework essential to a reasonable understanding of inhaled particles. The emphasis is placed on demonstrating the key roles of lung morphology on airflow and particle transport as well as identifying physical and biological factors that influence deposition. Special attention is paid to maintaining consistency of treatment and a balance between theoretical modeling and experimental measurements. The book covers all important aspects of inhaled particles including inhalability, aerosol dispersion, particle deposition, and clearance. It reviews concisely the basic background of lung morphology, respiratory physiology, aerodynamics, and aerosol science pertinent to the subject. Essential aspects of health effects and applications are also included. An easy-to-read, self contained introduction to the field An excellent source of updated research information Useful for students and professionals in aerosol science, environmental health science, occupational hygiene, health physics and biomedical engineering
Author: Jiyuan Tu
Publisher: Springer Science & Business Media
ISBN: 9400744870
Category : Technology & Engineering
Languages : en
Pages : 383
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Book Description
Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.
Author: Taylor Steven Geisler
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Prolonged exposure to inhaled micron-sized airborne particles is a known public health concern. These particles impact the health of staggering numbers of residents of polluted urban areas, as well as significant portions of the third world where it is still common to burn wood or charcoal indoors for cooking or heating. An understanding of the fate of inhaled particles in the lungs is useful for assessing their associated health risks, as well as improving the effectiveness of respiratory drug delivery techniques. The transport of microparticles is inseparable from behavior of the suspending airflow and this is studied using computational fluid dynamics techniques. The anatomy of the airways seems to have evolved to encourage turbulent airflow for functions such as mixing of flow to promote the warming and humidification of inhaled air, as well as for filtration. Large eddy simulation models are employed to capture turbulent flow in extremely complex patient-specific airway geometries. These collectively comprise the oral and nasal cavities, larynx, trachea, and the bronchial tree. The flow in anatomically-accurate rhesus macaque airways is also studied. Simulations are carried out for inspiratory flow rates corresponding to nominal Reynolds numbers in the hundreds to low-thousands yet somewhat surprisingly yield unsteady flows due to local geometric factors. A computed mean flow field is compared extensively with magnetic resonance velocimetry measurements carried out in the same computed-tomography--based lung geometry, showing good agreement. Microparticle deposition predictions are also verified. Focus is placed on the dynamics of the flow in the nasal airway, trachea, and bronchial tree. After becoming unsteady at constrictions in the upper airways, the flow is found to be chaotic, exhibiting fluctuations with broad-band spectra even at the most distal simulated airways in which the Reynolds numbers are as low as 300. The unsteadiness is attributed to the convection of turbulent structures produced in the upper airways as well as to local kinetic energy production throughout the bronchial tree.
Author: René Pomeau
Publisher:
ISBN: 9780729404938
Category :
Languages : en
Pages : 876
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Book Description
Author: Efstathios Michaelides
Publisher: CRC Press
ISBN: 1315354624
Category : Science
Languages : en
Pages : 1559
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Book Description
The Multiphase Flow Handbook, Second Edition is a thoroughly updated and reorganized revision of the late Clayton Crowe’s work, and provides a detailed look at the basic concepts and the wide range of applications in this important area of thermal/fluids engineering. Revised by the new editors, Efstathios E. (Stathis) Michaelides and John D. Schwarzkopf, the new Second Edition begins with two chapters covering fundamental concepts and methods that pertain to all the types and applications of multiphase flow. The remaining chapters cover the applications and engineering systems that are relevant to all the types of multiphase flow and heat transfer. The twenty-one chapters and several sections of the book include the basic science as well as the contemporary engineering and technological applications of multiphase flow in a comprehensive way that is easy to follow and be understood. The editors created a common set of nomenclature that is used throughout the book, allowing readers to easily compare fundamental theory with currently developing concepts and applications. With contributed chapters from sixty-two leading experts around the world, the Multiphase Flow Handbook, Second Edition is an essential reference for all researchers, academics and engineers working with complex thermal and fluid systems.
Author: Peter Gehr
Publisher: CRC Press
ISBN: 1420072579
Category : Medical
Languages : en
Pages : 324
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Book Description
Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the informat
Author: Amit Gefen
Publisher: Springer Science & Business Media
ISBN: 3642246184
Category : Technology & Engineering
Languages : en
Pages : 524
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Book Description
This book reviews the frontier of research and clinical applications of Patient Specific Modeling, and provides a state-of-the-art update as well as perspectives on future directions in this exciting field. The book is useful for medical physicists, biomedical engineers and other engineers who are interested in the science and technology aspects of Patient Specific Modeling, as well as for radiologists and other medical specialists who wish to be updated about the state of implementation.
