Novel Insights into the Comorbidities and Mortality in Patients with Diabetes

Novel Insights into the Comorbidities and Mortality in Patients with Diabetes PDF Author: Sen Li
Publisher: Frontiers Media SA
ISBN: 2832548164
Category : Medical
Languages : en
Pages : 144

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Book Description
Diabetes is a metabolic disorder of chronic hyperglycemia that causes numerous complications. The International Diabetes Federation and World Health Organization report that approximately 537 million people worldwide have diabetes in 2021, which may increase to 700 million by 2045. Diabetes and its complications significantly lower the quality of life of patients and cause more than 4 million deaths yearly. Diabetes and its complications also increase premature mortality, increasing society's economic burden. Numerous studies reveal that the chronic multisystem injury and dysfunction can be caused by diabetes, including cardiac and cerebral vascular lesions, nephropathy, retinopathy and neuropathy. In addition, diabetes usually co-occurs with other diseases that may have certain risk factors in common. For example, patients with diabetes are more likely to have hypertension, chronic obstructive pulmonary disease, or asthma. However, there is still a lack of knowledge on the relationship between diabetes and other potential comorbidities such as hepatitis infection, hearing impairment and periodontal disease. Furthermore, common risk factors contributing to the pathogenesis of diabetes and comorbidities are far from fully understood. Several comorbidities (e.g., cardiovascular and cerebrovascular diseases) raise the extra chances of death in patients with diabetes, but the association between diabetes and mortality of other diseases, such as endometrial or kidney cancer, is inconsistent. Further research is still needed to reveal the excess mortality associated with diabetic comorbidities.

Novel Insights into the Comorbidities and Mortality in Patients with Diabetes

Novel Insights into the Comorbidities and Mortality in Patients with Diabetes PDF Author: Sen Li
Publisher: Frontiers Media SA
ISBN: 2832548164
Category : Medical
Languages : en
Pages : 144

Get Book Here

Book Description
Diabetes is a metabolic disorder of chronic hyperglycemia that causes numerous complications. The International Diabetes Federation and World Health Organization report that approximately 537 million people worldwide have diabetes in 2021, which may increase to 700 million by 2045. Diabetes and its complications significantly lower the quality of life of patients and cause more than 4 million deaths yearly. Diabetes and its complications also increase premature mortality, increasing society's economic burden. Numerous studies reveal that the chronic multisystem injury and dysfunction can be caused by diabetes, including cardiac and cerebral vascular lesions, nephropathy, retinopathy and neuropathy. In addition, diabetes usually co-occurs with other diseases that may have certain risk factors in common. For example, patients with diabetes are more likely to have hypertension, chronic obstructive pulmonary disease, or asthma. However, there is still a lack of knowledge on the relationship between diabetes and other potential comorbidities such as hepatitis infection, hearing impairment and periodontal disease. Furthermore, common risk factors contributing to the pathogenesis of diabetes and comorbidities are far from fully understood. Several comorbidities (e.g., cardiovascular and cerebrovascular diseases) raise the extra chances of death in patients with diabetes, but the association between diabetes and mortality of other diseases, such as endometrial or kidney cancer, is inconsistent. Further research is still needed to reveal the excess mortality associated with diabetic comorbidities.

Managing Diabetes and Hyperglycemia in the Hospital Setting

Managing Diabetes and Hyperglycemia in the Hospital Setting PDF Author: Boris Draznin
Publisher: American Diabetes Association
ISBN: 1580406572
Category : Medical
Languages : en
Pages : 338

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Book Description
As the number of patients with diabetes increases annually, it is not surprising that the number of patients with diabetes who are admitted to the hospital also increases. Once in the hospital, patients with diabetes or hyperglycemia may be admitted to the Intensive Care Unit, require urgent or elective surgery, enteral or parenteral nutrition, intravenous insulin infusion, or therapies that significantly impact glycemic control (e.g., steroids). Because many clinical outcomes are influenced by the degree of glycemic control, knowledge of the best practices in inpatient diabetes management is extremely important. The field of inpatient management of diabetes and hyperglycemia has grown substantially in the last several years. This body of knowledge is summarized in this book, so it can reach the audience of hospitalists, endocrinologists, nurses and other team members who take care of hospitalized patients with diabetes and hyperglycemia.

Chronic Kidney Disease - Novel Insights into Pathophysiology and Treatment

Chronic Kidney Disease - Novel Insights into Pathophysiology and Treatment PDF Author: Giovanni Palleschi
Publisher: BoD – Books on Demand
ISBN: 0854666532
Category : Medical
Languages : en
Pages : 184

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Book Description
In clinical practice, all physicians have to deal with patients suffering from chronic kidney disease. Large numbers of these patients suffer from mild conditions, but nevertheless, they deserve special attention because inappropriate management may accelerate kidney function deterioration. On the other side, patients affected by end-stage renal disease require replacement therapies and often represent a challenge for clinicians due to their complex pathophysiology. Therefore, an adequate knowledge of the most important clinical and therapeutic aspects of renal failure is an essential requirement for every doctor, especially if we consider the increasing incidence and prevalence of this condition. The book summarises the most important etiopathogenetic and pathophysiologic aspects of chronic kidney disease and focuses the attention on important emerging topics: nutritional and dietary management, renoprotective interventions, new evidence about pathophysiological mechanisms provided by base research, innovations in pharmacological treatment, and strategies to improve patient’s quality of life. Data are reported in clear and concise language, supported by graphics, tables, and pictures that facilitate the comprehension of all the arguments.

Depression and Diabetes

Depression and Diabetes PDF Author: Wayne Katon
Publisher: John Wiley & Sons
ISBN: 1119957478
Category : Medical
Languages : en
Pages : 197

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Book Description
In recent years, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. The WPA is providing an update of currently available evidence on these interrelationships by the publication of three books, dealing with the comorbidity of depression with diabetes, heart disease and cancer. Depression is a frequent and serious comorbid condition in diabetes, which adversely affects quality of life and the long-term prognosis. Co-occurrent depression presents peculiar clinical challenges, making both conditions harder to manage. Depression and Diabetes is the first book devoted to the interaction between these common disorders. World leaders in diabetes, depression and public health synthesize current evidence, including some previously unpublished data, in a concise, easy-to-read format. They provide an overview of the epidemiology, pathogenesis, medical costs, management, and public health and cultural implications of the comorbidity between depression and diabetes. The book describes how the negative consequences of depression in diabetes could be avoided, given that effective depression treatments for diabetic patients are available. Its practical approach makes the book ideal for all those involved in the management of these patients: psychiatrists, psychologists, diabetologists, general practitioners, diabetes specialist nurses and mental health nurses.

Novel Insights into Obesity-Related Diseases

Novel Insights into Obesity-Related Diseases PDF Author: Sanyuan Hu
Publisher: Frontiers Media SA
ISBN: 2889766020
Category : Science
Languages : en
Pages : 138

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Book Description


Disease Control Priorities, Third Edition (Volume 5)

Disease Control Priorities, Third Edition (Volume 5) PDF Author: Dorairaj Prabhakaran
Publisher: World Bank Publications
ISBN: 1464805202
Category : Medical
Languages : en
Pages : 948

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Book Description
Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Advances in Patient Safety

Advances in Patient Safety PDF Author: Kerm Henriksen
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 526

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Book Description
v. 1. Research findings -- v. 2. Concepts and methodology -- v. 3. Implementation issues -- v. 4. Programs, tools and products.

Diabetes in America

Diabetes in America PDF Author:
Publisher:
ISBN:
Category : Diabetes
Languages : en
Pages : 804

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Book Description


Hypertension and Cardiovascular Disease

Hypertension and Cardiovascular Disease PDF Author: Emmanuel A. Andreadis
Publisher: Springer
ISBN: 3319395998
Category : Medical
Languages : en
Pages : 392

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Book Description
This book provides comprehensive analysis into individualized patient care, and applying evidence‐based medicine while integrating basic medical knowledge with applied medicine. The Editor and the contributors not only discuss important issues on hypertension management and its deleterious consequences if it is not well‐controlled, but also highlight the important signaling pathways involved in the pathogenesis of hypertensive heart disease and cardiac hypertrophy.

Cardiovascular and Metabolic Comorbidities in Pituitary Disorders

Cardiovascular and Metabolic Comorbidities in Pituitary Disorders PDF Author: Pawel Krzesinski
Publisher: Frontiers Media SA
ISBN: 2832550347
Category : Science
Languages : en
Pages : 108

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Book Description
Pituitary disorders may be associated with an increased risk of cardiovascular and metabolic complications and, in consequence, increased mortality. Excessive secretion of pituitary hormones provokes functional and systemic abnormalities which can be manifested by cardiovascular complications such as eg. arterial hypertension, heart failure, arrhythmia, as through metabolic disturbances, including obesity and diabetes. Subclinical effects of pituitary diseases, such as cardiac and vascular dysfunction, also modifies prognosis but due to its asymptomatic course are frequently diagnosed with significant time delay. Even successful surgery and pharmacological treatment of pituitary disorders do not guarantee that metabolic and cardiovascular comorbidities can be completely resolved after primary disease remission. This Research Topic aims to provide insights into the cross-talk between pituitary and cardiometabolic disorders in respect to effective diagnosis and targeted therapy. We also especially welcome studies that advance our knowledge on molecular mechanisms and pathogenic pathways explaining these phenomena. Another issue that still needs clarification is an effective model of interdisciplinary care focused on holistic approach to patients with pituitary disorders. We would like to turn on a light of attention towards the importance of psychological, dietary, and rehabilitation care. We aim to collect the up-to-date studies presenting novel results and future perspectives in this area. In this Research Topic, we welcome the submission of original research, reviews, and expert opinions, that include but are not limited to the following areas in pituitary disorders: • prevalence of cardiovascular and metabolic comorbidities • molecular mechanisms and pathogenic pathways of cardiovascular and metabolic complications • novel diagnostic tools and biochemical markers to detect early cardiovascular and metabolic complications • individualized treatment of cardiovascular and metabolic complications • reversibility of cardiovascular and metabolic abnormalities after biochemical control of primary endocrine dysfunction • optimal model of interdisciplinary care • diet, psychological support, rehabilitation