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Author: Karime Khoukh
Publisher:
ISBN:
Category :
Languages : fr
Pages : 87
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Book Description
Author: Karime Khoukh
Publisher:
ISBN:
Category :
Languages : fr
Pages : 87
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Author: Julien Deschamps
Publisher:
ISBN:
Category :
Languages : fr
Pages : 332
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Book Description
Le cancer du sein est la forme la plus répandue de cancer chez la femme. Grâce aux programmes de dépistage, le taux de patientes présentant un cancer du sein à un stade précoce s'accroît, il est actuellement de 50 %. La chirurgie reste alors le premier traitement, avec des taux de guérison variables (environ 40%). Il n'existe pas de manière fiable pour essayer d'identifier les patientes qui seront guéries et celles qui feront une rechute. C'est pourquoi, une thérapie adjuvante est habituellement préconisée après l'acte chirurgical afin de détruire toutes les cellules cancéreuses pouvant persister sur le site primitif. Le traitement de rechutes, qui surviennent chez 60% des patientes, fait appel essentiellement à la thérapie hormonale et à la chimiothérapie. L'hormonothérapie est l'un des traitements du cancer du sein. Il s'agit d'un traitement adjuvant, c'est à dire qu'il permet d'éviter les récidives, il complète ou non un traitement chirurgical ou une chimiothérapie. En effet, la glande mammaire est tout au long de la vie soumise à l'influence des hormones sexuelles (estrogènes et progestérone). Le cancer du sein peut se développer sous l'influence de ces hormones et y être plus ou moins sensible. Les antiaromatases constituent actuellement un réel progrès à tous les stades de la maladie par rapport au tamoxifène, qui était jusqu'à présent le " gold standard " que ce soit en termes d'efficacité ou de profil de tolérance. En effet, le tamoxifène administré en traitement adjuvant pendant 5 ans chez des patientes avec un cancer du sein ayant des récepteurs hormonaux positifs a été pendant plus de 20 ans le traitement standard international. Il entraîne une réduction de risque de décès de 25 %. Plus récemment, des résultats d'essais comparant un traitement adjuvant par inhibiteurs d'aromatase et par tamoxifène ont été rapportés. Ils montrent une efficacité des inhibiteurs d'aromatases supérieure à celle du tamoxifène sur le risque de rechute, qu'il s'agisse d'études comparatives (anastrozole) ou séquentielles (anastrozole, létrozole et exémestane). Mais plusieurs questions restent aujourd'hui sans réponse. -la durée optimale de traitement. -la définition de la séquence optimale de traitement et l'intérêt d'un traitement séquentiel (antiestrogènes suivi d'inhibiteurs de l'aromatase ou la séquence inverse). -et enfin la tolérance à long terme. Il est par ailleurs important que l'évaluation des anti-aromatases se poursuive pour disposer de plusieurs essais, avec des résultats à long terme, pour répondre à chacune des questions posées.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : fr
Pages : 544
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Author: Leszek Szablewski
Publisher: BoD – Books on Demand
ISBN: 178985525X
Category : Medical
Languages : en
Pages : 140
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Book Description
The main source of energy for the body is glucose. Its low blood concentrations can cause seizures, loss of consciousness and death. Long lasting high glucose levels can cause blindness, renal failure, cardiac and peripheral vascular disease, and neuropathy. Blood glucose concentrations need to be maintained within narrow limits. The process of maintaining blood glucose at a steady state is called glucose homeostasis. This is achieved through a balance of the rate of consumption of dietary carbohydrates, utilization of glucose by peripheral tissues, and the loss of glucose through the kidney tubule. The liver and kidney also play a role in glucose homeostasis. This book aims to provide an overview of blood glucose levels in health and diseases.
Author: Alan D. Lopez
Publisher: World Bank Publications
ISBN: 0821362631
Category : Medical
Languages : en
Pages : 511
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Book Description
Strategic health planning, the cornerstone of initiatives designed to achieve health improvement goals around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors and the likely effects of invervention options. The Global Burden of Disease framework, originally published in 1990, has been widely adopted as the preferred method for health accounting and has become the standard to guide the setting of health research priorities. This publication sets out an updated assessment of the situation, with an analysis of trends observed since 1990 and a chapter on the sensitivity of GBD estimates to various sources of uncertainty in methods and data.
Author:
Publisher:
ISBN:
Category : Accidents
Languages : fr
Pages : 604
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Author: Laszlo Muszbek
Publisher: CRC Press
ISBN: 1000013308
Category : Medical
Languages : en
Pages : 278
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Book Description
First Published in 1987: The book is to give insight into the multisided relationship of hemostatic systems and malignancies and to help biomedical scientists and practicing clinicians obtain a better understanding of cancer research.
Author: Vern L. Katz
Publisher: Mosby
ISBN:
Category : Medical
Languages : en
Pages : 1138
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Book Description
Formerly edited by Drs. Droegemueller, Stenchever, Mishell & Herbst - this trusted and tested reference provides complete, timely, and easy access to vital information on the medical and surgical issues affecting today's daily gynecology practice. Featuring the fresh perspectives of four new editors, along with new contributors, the text offers practical, in-depth coverage...helpful illustrations - many new to this edition...and clinically oriented guidance...page after page! Plus, access the complete contents online, fully searchable at www.compgyn.com - so you can find quick answers from an location. Access state-of-the-art guidance on the latest minimally invasive surgical techniques...the newest applications in diagnostic and interventional ultrasound...and many other essential aspects of today's practice. Access fresh practice perspectives from four new editors and new contributors. Effectively handle the emotional aspects of the specialty with unique new chapters covering rape * incest * and domestic violence, among others. Diagnose conditions accurately with the visual aid of nearly 1,000 illustrations - including more than 100 new full-color photos. Quickly find the information you need with user-friendly features including key terms, key points, and the use of color throughout. Exponentially boost your clinical reference power with access to the complete contents online - fully searchable - as well as all of the illustrations for use in electronic presentations. Visit www.compgyn.com for details. Presents the work of four new associate editors and many new contributors who offer fresh practice perspectives. Includes unique new chapters covering rape . incest . domestic violence . and other highly emotional aspects of the specialty. Features more than 100 new full-color photos that help you identify lesions and interpret pathologic findings. Provides expanded material on menopause, reflecting the ever-increasing aging patient population.
Author: Giovanna Gatti
Publisher: Springer
ISBN: 3319163787
Category : Medical
Languages : en
Pages : 91
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Book Description
This book explains how telemedicine can offer solutions capable of improving the care and survival rates of cancer patients and can also help patients to live a normal life in spite of their condition. Different fields of application – community, hospital and home based – are examined, and detailed attention is paid to the use of tele-oncology in rural/extreme rural settings and in developing countries. The impact of new technologies and the opportunities afforded by the social web are both discussed. The concluding chapters consider eLearning in relation to cancer care and assess the scope for education to improve prevention. No medical condition can shatter people’s lives as cancer does today and the need to develop strategies to reduce the disease burden and improve quality of life is paramount. Readers will find this new volume in Springer’s TELe Health series to be a rich source of information on the important contribution that can be made by telemedicine in achieving these goals.
Author: P.J. Hauri
Publisher: Springer Science & Business Media
ISBN: 9780306437915
Category : Medical
Languages : en
Pages : 274
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Book Description
Sleep disorder experts discuss specific behavioral techniques, psychotherapeutic techniques and pharmacotherapy, comprehensive and integrated approaches, disorders of the sleep-wake schedule, and specific populations--the chronically ill and older adults. The field has seen rapid advances in recent years and has attained growing respectability--insomnia is now seen as something more than a manifestation of depression or simply an annoying nuisance to be extinguished with hyponotics. Annotation copyrighted by Book News, Inc., Portland, OR
