New Concepts of Psychostimulants Induced Neurotoxicity

New Concepts of Psychostimulants Induced Neurotoxicity PDF Author: Hari Shanker Sharma
Publisher: Academic Press
ISBN: 0080922902
Category : Science
Languages : en
Pages : 501

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Book Description
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. With recent advancements in new knowledge, it has become evident that psychostimulants and related drugs of abuse are influencing our central nervous system (CNS) remarkably and could alter their function for a longtime. This volume is the first to focus on substance abuse induced brain pathology in the widest sense as it covers alterations in neuronal, glial and endothelial cell functions under the influence of acute or chronic usage of substance abuse.

New Concepts of Psychostimulants Induced Neurotoxicity

New Concepts of Psychostimulants Induced Neurotoxicity PDF Author: Hari Shanker Sharma
Publisher: Academic Press
ISBN: 0080922902
Category : Science
Languages : en
Pages : 501

Get Book Here

Book Description
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. With recent advancements in new knowledge, it has become evident that psychostimulants and related drugs of abuse are influencing our central nervous system (CNS) remarkably and could alter their function for a longtime. This volume is the first to focus on substance abuse induced brain pathology in the widest sense as it covers alterations in neuronal, glial and endothelial cell functions under the influence of acute or chronic usage of substance abuse.

Environmental Neurotoxicology

Environmental Neurotoxicology PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309045312
Category : Science
Languages : en
Pages : 167

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Book Description
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Behavioral Measures of Neurotoxicity

Behavioral Measures of Neurotoxicity PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309040477
Category : Science
Languages : en
Pages : 449

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Book Description
Exposure to toxic chemicalsâ€"in the workplace and at homeâ€"is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.

Neural Circuits and Networks

Neural Circuits and Networks PDF Author: Vincent Torre
Publisher: Springer Science & Business Media
ISBN: 3642589553
Category : Computers
Languages : en
Pages : 245

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Book Description
The understanding of parallel processing and of the mechanisms underlying neural networks in the brain is certainly one of the most challenging problems of contemporary science. During the last decades significant progress has been made by the combination of different techniques, which have elucidated properties at a cellular and molecular level. However, in order to make significant progress in this field, it is necessary to gather more direct experimental data on the parallel processing occurring in the nervous system. Indeed the nervous system overcomes the limitations of its elementary components by employing a massive degree of parallelism, through the extremely rich set of synaptic interconnections between neurons. This book gathers a selection of the contributions presented during the NATO ASI School "Neuronal Circuits and Networks" held at the Ettore Majorana Center in Erice, Sicily, from June 15 to 27, 1997. The purpose of the School was to present an overview of recent results on single cell properties, the dynamics of neuronal networks and modelling of the nervous system. The School and the present book propose an interdisciplinary approach of experimental and theoretical aspects of brain functions combining different techniques and methodologies.

Methods of Behavior Analysis in Neuroscience

Methods of Behavior Analysis in Neuroscience PDF Author: Jerry J. Buccafusco
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341

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Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

The Effects of Drug Abuse on the Human Nervous System

The Effects of Drug Abuse on the Human Nervous System PDF Author: Bertha Madras
Publisher: Elsevier
ISBN: 0124186858
Category : Psychology
Languages : en
Pages : 625

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Book Description
Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. - A comprehensive reference on the effects of drug addiction on the human nervous system - Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs - Includes foundational science chapters on the biology of addiction - Details challenges in diagnosis and treatment options

Clinical Neurotoxicology E-Book

Clinical Neurotoxicology E-Book PDF Author: Michael R. Dobbs
Publisher: Elsevier Health Sciences
ISBN: 032307099X
Category : Medical
Languages : en
Pages : 729

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Book Description
Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You’ll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors—such as heavy metals and pesticides—and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. Provides a complete listing of neurotoxic agents—from manufactured to environmental—so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson’s Disease, motor neuron disease, as well as other issues that are still in question.

Caffeine in Food and Dietary Supplements

Caffeine in Food and Dietary Supplements PDF Author: Leslie A. Pray
Publisher:
ISBN: 9780309297493
Category : Health & Fitness
Languages : en
Pages : 0

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Book Description
Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.

Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts

Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts PDF Author: Arpad Szallasi
Publisher: MDPI
ISBN: 3038426385
Category : Medical
Languages : en
Pages : 247

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Book Description
This book is a printed edition of the Special Issue "Transient Receptor Potential (TRP) Channels in Drug Discovery: Old Concepts & New Thoughts" that was published in Pharmaceuticals

Behavioral Toxicology

Behavioral Toxicology PDF Author: Bernard Weiss
Publisher: Springer Science & Business Media
ISBN: 1468428594
Category : Science
Languages : en
Pages : 475

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Book Description
Behavioral toxicology is a young discipline in the United States; so young, in fact, that this is one of its first books. Behavioral questions are bound to play a major role in future scientific work and governmental decisions involving the health effects of environmental contaminants and other chemicals. This role springs from two key problems that face scientists and public agencies required to set acceptable exposure standards or to determine criteria for the toxicity of therapeutic chemicals: How do you evaluate effects that may show up only as subtle functional disturbances? And how do you de tect toxic effects early enough so that they may still be reversible, before they produce major damage? The contributions in this book come from a collection of scientists whose interests span a wide variety of problem areas. The focus is largely on me thodological issues because they represent the most immediate concern of the discipline. We expect that this collection of papers will represent a useful source book for behavioral toxicology for some time. For the past few years, the University of Rochester's Department of Radiation Biology and Biophysics has sponsored a series of international conferences on chemical toxicity, partly as a response to concern over the con sequences to health of the rich chemical soup in which we live. This book is based upon presentations made to the fifth of the series. Held in June, 1972, it was the first formal meeting devoted to behavioral toxicology in this country.