The Neuropathology of Schizophrenia PDF Download
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Author: Paul J. Harrison
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 402
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Book Description
What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.
Author: Paul J. Harrison
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 402
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Book Description
What is schizophrenia? This is one of the most controversial questions in psychiatry and mental health research; however, in the last twenty years, there have been significant advances in our understanding of the topic. This book provides a balanced, comprehensive and up-to-date overview of the neuropathology of schizophrenia and its interpretation, covering the latest evidence derived from all fields of research, from brain scans to microscopy. The authors include many of the foremost international authorities in this rapidly developing field.
Author: Ted Abel
Publisher: Academic Press
ISBN: 0128018771
Category : Psychology
Languages : en
Pages : 470
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Book Description
The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. - Provides a comprehensive overview of neurobiological aspects of schizophrenia - Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels - Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance - Elucidates connections between the various systems depicted, when possible
Author: Gareth W. Roberts
Publisher: Cambridge University Press
ISBN: 9780521425582
Category : Medical
Languages : en
Pages : 204
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Book Description
This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.
Author: Daniel Roy Weinberger
Publisher:
ISBN:
Category : Brain
Languages : en
Pages : 18
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Book Description
Author: David L. Clark
Publisher: Cambridge University Press
ISBN: 9780521840507
Category : Medical
Languages : en
Pages : 290
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Book Description
New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.
Author: Perminder S. Sachdev
Publisher: Cambridge University Press
ISBN: 1139485229
Category : Medical
Languages : en
Pages :
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Book Description
Schizophrenia may not be a single disease, but the result of a diverse set of related conditions. Modern neuroscience is beginning to reveal some of the genetic and environmental underpinnings of schizophrenia; however, an approach less well travelled is to examine the medical disorders that produce symptoms resembling schizophrenia. This book is the first major attempt to bring together the diseases that produce what has been termed 'secondary schizophrenia'. International experts from diverse backgrounds ask the questions: does this medical disorder, or drug, or condition cause psychosis? If yes, does it resemble schizophrenia? What mechanisms form the basis of this relationship? What implications does this understanding have for aetiology and treatment? The answers are a feast for clinicians and researchers of psychosis and schizophrenia. They mark the next step in trying to meet the most important challenge to modern neuroscience – understanding and conquering this most mysterious of human diseases.
Author: Stephen J. Wood
Publisher: Cambridge University Press
ISBN: 0521862892
Category : Medical
Languages : en
Pages : 465
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Book Description
Describes neuropsychological approaches to the investigation, description, measurement and management of a wide range of mental illnesses.
Author: Matthew Williams
Publisher: Springer Nature
ISBN: 3030683087
Category : Medical
Languages : en
Pages : 240
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Book Description
In the past few decades, neuropathology has witnessed a resurgence. The rise of structural and functional imaging techniques has allowed pathological studies to target regions of special interest as revealed by whole-brain techniques, and the development of comprehensive software packages has facilitated cellular and pathological measurements. Furthermore, a new generation of antibodies and improved staining methods has made the field more accessible to researchers and revealed more detail than could once have been envisaged. Perhaps most important of all has been the sourcing of high-quality tissue through modern, large-scale databases covering multiple tissue banks, removing much of the heterogeneity that had made repeat studies all but impossible. The Neuropathology of Schizophrenia reviews the field following these recent improvements in techniques and contrasting more modern methods against older studies. This book presents the current state of neuropathological knowledge in schizophrenia by means of examination of neuropathology as informed by functional systems. It starts by considering the frontal cortical region, a particularly well-examined region of the brain, before moving through other cortical regions, subcortical pathways and the deep white matter. In addition, potential new routes for investigation are considered, particularly in glial cells.
Author: Steven M. Silverstein
Publisher: MIT Press
ISBN: 0262019620
Category : Medical
Languages : en
Pages : 403
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Book Description
Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment. Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment. The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability. Contributors Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes
Author: Marek Kubicki
Publisher: Springer Nature
ISBN: 3030352064
Category : Medical
Languages : en
Pages : 432
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Book Description
This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.
