Neuroinflammation

Neuroinflammation PDF Author: Alireza Minagar
Publisher: Elsevier
ISBN: 0123849144
Category : Medical
Languages : en
Pages : 541

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Book Description
Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. - Comprehensive review of the latest developments in neuroinflammation - Includes contributions from leading authorities

Neuroinflammation

Neuroinflammation PDF Author: Alireza Minagar
Publisher: Elsevier
ISBN: 0123849144
Category : Medical
Languages : en
Pages : 541

Get Book Here

Book Description
Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. - Comprehensive review of the latest developments in neuroinflammation - Includes contributions from leading authorities

Neuroinflammation and Schizophrenia

Neuroinflammation and Schizophrenia PDF Author: Golam M. Khandaker
Publisher: Springer
ISBN: 9783030391409
Category : Medical
Languages : en
Pages : 244

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Book Description
This book provides a comprehensive summary of the cutting edge scientific evidence regarding the role of immune system in the pathogenesis and treatment of schizophrenia and related psychotic disorders. It illustrates the role of inflammation and immunity in schizophrenia drawing on both basic science and clinical research. The chapters provide up-to-date summaries of immunological risk factors for schizophrenia and related psychotic disorders, and underlying mechanisms as informed by neuroimaging, genetic, clinical and animal experimental studies. In addition, the book will illuminate the scope for immunological treatment for schizophrenia.

Mechanisms of Neuroinflammation

Mechanisms of Neuroinflammation PDF Author: Gonzalo Emiliano Aranda Abreu
Publisher: BoD – Books on Demand
ISBN: 9535134515
Category : Medical
Languages : en
Pages : 320

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Book Description
"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.

Neuroinflammation, Resolution, and Neuroprotection in the Brain

Neuroinflammation, Resolution, and Neuroprotection in the Brain PDF Author: Akhlaq A. Farooqui
Publisher: Academic Press
ISBN: 032388461X
Category : Medical
Languages : en
Pages : 334

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Book Description
Neuroinflammation, Resolution, and Neuroprotection in the Brain discusses the molecular aspects of neuroinflammation in neurological disorders. The book examines the effect of diet and exercise on neuroinflammatory diseases. Chapters focus on bioactive lipids, cytokines and chemokines, as well as the involvement of neuroinflammation, resolution and neuroprotection in neurotraumatic diseases, neurodegenerative diseases and neuropsychiatric diseases. The comprehensive information in this monograph will help readers understand molecular cross-talk among mediators of phospholipid, sphingolipid and cholesterol metabolism. The book's goal is to jumpstart more studies on molecular mechanisms and the therapeutic aspects of neurological disorders in human subjects. - Discusses the molecular aspects of neuroinflammation, resolution and neuroprotection - Examines the role of diet and exercise on neuroinflammatory diseases - Provides cutting-edge research on signal transduction processes - Explores the treatment of neurological disorders caused by neuroinflammation

Neuron-Glia Interaction in Neuroinflammation

Neuron-Glia Interaction in Neuroinflammation PDF Author: Akio Suzumura
Publisher: Springer Science & Business Media
ISBN: 1461483131
Category : Medical
Languages : en
Pages : 192

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Book Description
Accumulation on glia is an active pathological element in many neurological disorders. Gliosis produces neuroinflammation through both neurotrophic and inflammatory means, but the exact mechanism through which this happens remain unclear. It is suspected that damage to neurons activates the growth of glial cells. The proposed book focuses on the interaction between neurons and glia to help elucidate the pathophysiology of neuroinflammation in neurological disorders.​

Type 2 Diabetes and Dementia

Type 2 Diabetes and Dementia PDF Author: Velandai Srikanth
Publisher: Academic Press
ISBN: 0128096942
Category : Medical
Languages : en
Pages : 322

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Book Description
Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. - Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics - Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology - Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications

Neuro-inflammation in Neuronal Death and Repair

Neuro-inflammation in Neuronal Death and Repair PDF Author: Giacinto Bagetta
Publisher: Academic Press
ISBN: 0123739896
Category : Medical
Languages : en
Pages : 500

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Book Description
A current review of the mechanisms of neuroinflammation and their role in neurodegenerative disorders.

Animal Models of Acute Neurological Injuries

Animal Models of Acute Neurological Injuries PDF Author: Jun Chen
Publisher: Humana Press
ISBN: 9781617378775
Category : Medical
Languages : en
Pages : 0

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Book Description
Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.

Inflammatory Disorders of the Nervous System

Inflammatory Disorders of the Nervous System PDF Author: Alireza Minagar
Publisher: Humana Press
ISBN: 331951220X
Category : Medical
Languages : en
Pages : 283

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Book Description
This thoroughly updated edition covers all clinical aspects of neuroinflammation. The latest developments in pathogenesis and advances in treatment are provided, along with an understanding of the immune system's role and interactions between the activated immune cells, cerebral endothelial cells, and other main components of the immune cascade. Cutting-edge and authoritative, this volume offers practitioners a valuable resource for research and clinical practice.

The Blood Brain Barrier and Inflammation

The Blood Brain Barrier and Inflammation PDF Author: Ruth Lyck
Publisher: Springer
ISBN: 9783319833088
Category : Medical
Languages : en
Pages : 0

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Book Description
This PIR volume presents a comprehensive collection of reviews that focus on the role of the blood-brain barrier (BBB) during steady-state and inflamed conditions. Within the central nervous system (CNS) the constantly changing bloodstream is strictly separated from the CNS parenchyma by the BBB. However, viruses, bacteria, parasites and auto-aggressive immune cells can penetrate the barrier and significantly contribute to CNS inflammation. The BBB can actively contribute to neuroinflammation by presentation of chemokines, expression of cell adhesion molecules and alterations of barrier properties. As such, understanding the role of the BBB under healthy and pathological conditions is essential to the development of new drugs to efficiently combat inflammatory diseases of the CNS.