Navigating the Complexities of SARS-CoV-2 Immunobiology: The Science Behind the COVID-19 Pandemic

Navigating the Complexities of SARS-CoV-2 Immunobiology: The Science Behind the COVID-19 Pandemic PDF Author:
Publisher: Academic Press
ISBN: 9780443238321
Category : Science
Languages : en
Pages : 0

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Book Description
Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

Navigating the Complexities of SARS-CoV-2 Immunobiology: The Science Behind the COVID-19 Pandemic

Navigating the Complexities of SARS-CoV-2 Immunobiology: The Science Behind the COVID-19 Pandemic PDF Author:
Publisher: Academic Press
ISBN: 9780443238321
Category : Science
Languages : en
Pages : 0

Get Book Here

Book Description
Navigating Complexities of the SARS-CoV-2 Immunobiology: The Science behind the COVID-19 Pandemic offers a comprehensive exploration of the immune response to COVID-19. This volume brings together research and insights from leading experts to address key aspects of COVID-19 immunology, including T cell responses, cytokine storms, immune evasion strategies, and the impact on preexisting conditions. It also examines the long-term implications of the disease, such as long COVID and its intersection with autoimmunity, as well as the role of the microbiome. This compilation provides a deep understanding of the durability of immune responses post-infection and vaccination, presenting novel perspectives on therapeutic approaches and the path forward in combating this global pandemic.

When Corona Meets Darwin

When Corona Meets Darwin PDF Author: ZHAOBIN. WEI XU (DONGQING.)
Publisher:
ISBN: 9781036405311
Category :
Languages : en
Pages : 0

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Book Description
Delve into the intricate world of infectious diseases and viral dynamics in ' When Corona Meets Darwin: Exploring the Science Behind COVID-19.' From debunking misconceptions about herd immunity to unraveling the mysterious disappearance of SARS, this book takes readers on a compelling journey through the complexities of pandemics. Explore the inner workings of the human immune system, the evolution of viruses like SARS-CoV-2, and the challenges in developing vaccines for global health threats. With insightful discussions on the impact of viral heterogeneity and the consequences of China's dynamic-zero policies, ' When Corona Meets Darwin: Exploring the Science Behind COVID-19' offers a thought-provoking exploration of the science behind infectious diseases and the strategies for combating them. This groundbreaking book reconstructs a new theoretical framework in computational immunology in an accessible and innovative manner. This book is an essential read for anyone seeking a deeper understanding of the current and future landscape of global health.

Immunobiology of COVID-19

Immunobiology of COVID-19 PDF Author:
Publisher: Elsevier
ISBN: 0443132852
Category : Science
Languages : en
Pages : 262

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Book Description
This volume provides a comprehensive and in-depth exploration of the SARS-CoV-2 virus and its impact on human health. Written by a team of expert contributors, the book covers various aspects of the virus, including its structure, life cycle, and genomic replication. It delves into the epidemiology of COVID-19, comparing it with other related coronaviruses and discussing the concept of herd immunity. The structural biology of SARS-CoV-2 is examined, with a focus on techniques such as electron microscopy and cryo-electron tomography. The book also explores the biology of SARS-CoV-2 variants and their immune evasion strategies. Furthermore, it delves into the pathogenesis of COVID-19, examining its multiorgan manifestations and the long-term effects of the disease. The innate and adaptive immune responses to SARS-CoV-2 are discussed in detail, along with the role of B cells and T cells in the immune response. The volume concludes with a look at future insights and potential developments in the field. Accompanied by illustrative diagrams and visuals, this volume would aid in grasping complex concepts, serving as a valuable resource for researchers, healthcare professionals, and anyone interested in understanding the intricate details of SARS-CoV-2 and its impact on global health. - Comprehensive coverage of various aspects of the COVID-19 pandemic, including virus structure, variants, immune responses, disease pathogenesis including its multiorgan manifestations and long COVID - Focus on in-depth analysis of innate and adaptive immune responses to SARS-CoV-2, including B cell and T cell responses, discussing the recognition and activation mechanisms, antibody production, immunological memory as well as the role of spike proteins in immunological regulation - Richly illustrated with informative diagrams, providing visual aids to enhance understanding of complex concepts and structures related to COVID-19

Management of Legionella in Water Systems

Management of Legionella in Water Systems PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030949382X
Category : Medical
Languages : en
Pages : 291

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Book Description
Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.

Nijkamp and Parnham's Principles of Immunopharmacology

Nijkamp and Parnham's Principles of Immunopharmacology PDF Author: Michael J. Parnham
Publisher: Springer Nature
ISBN: 3030108112
Category : Medical
Languages : en
Pages : 888

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Book Description
Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks. The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests. Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions. The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.

Trained Immunity-based Vaccines

Trained Immunity-based Vaccines PDF Author: Jose Luis Subiza
Publisher: Frontiers Media SA
ISBN: 2889712311
Category : Medical
Languages : en
Pages : 195

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Book Description
Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.

The Vaccine Book

The Vaccine Book PDF Author: Barry R. Bloom
Publisher: Academic Press
ISBN: 012805400X
Category : Medical
Languages : en
Pages : 666

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Book Description
The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child's risk. - Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines - Gives new ideas about future vaccines and concepts - Introduces new vaccines and concepts - Gives ideas about challenges facing public and private industrial investors in the vaccine area - Discusses the problem of declining immunization rates and vaccine hesitancy

Multiple Sclerosis

Multiple Sclerosis PDF Author: Alireza Minagar
Publisher: Academic Press
ISBN: 0128010053
Category : Science
Languages : en
Pages : 540

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Book Description
Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS. The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS. It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study. Focuses on the pathophysiologic mechanisms of multiple sclerosis and the mechanisms of action in agents for the treatment of MS Discusses the roles of neurodegeneration and neuroregeneration in MS and related diseases Authored and edited by international leaders in the field of MS research

Coronavirus Disease 2019 (COVID-19)

Coronavirus Disease 2019 (COVID-19) PDF Author: Shailendra K. Saxena
Publisher:
ISBN: 9789811548154
Category : Coronavirus infections
Languages : en
Pages :

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Book Description
This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing various aspects of COVID-19 infection, including global epidemiology, genome organization, immunopathogenesis, transmission cycle, diagnosis, treatment, prevention, and control strategies, it highlights host-pathogen interactions, host immune response, and pathogen immune invasion strategies toward developing an immune intervention or preventive vaccine for COVID-19. An understanding of the topics covered in the book is imperative in the context of designing strategies to protect the human race from further losses and harm due to SARS-CoV-2 infection causing COVID-19.

Blood and Marrow Transplant Handbook

Blood and Marrow Transplant Handbook PDF Author: Richard T. Maziarz
Publisher: Springer
ISBN: 3319138324
Category : Medical
Languages : en
Pages : 437

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Book Description
This updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant patients. Spanning the timeline from the initial consultation throughout the transplant process, this handbook includes indications for transplantation and donor selection, treatment guidelines for addressing complications during and after transplant, and recommendations for long-term follow up care. Concise, comprehensive, and easy-to-use, Blood and Marrow Transplant Handbook, 2nd Edition presents a multidisciplinary approach to information for physicians and advanced practice medical providers who care for transplant patients, and also residents, fellows, and other trainees.