NINDS at 50

NINDS at 50 PDF Author: Lewis P. Rowland
Publisher:
ISBN:
Category :
Languages : en
Pages : 348

Get Book Here

Book Description


Neurological, Psychiatric, and Developmental Disorders

Neurological, Psychiatric, and Developmental Disorders PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309170931
Category : Medical
Languages : en
Pages : 458

Get Book Here

Book Description
Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.

Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans

Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309486890
Category : Medical
Languages : en
Pages : 211

Get Book Here

Book Description
The Veterans Benefits Administration (VBA) provides disability compensation to veterans with a service-connected injury, and to receive disability compensation from the Department of Veterans Affairs (VA), a veteran must submit a claim or have a claim submitted on his or her behalf. Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans reviews the process by which the VA assesses impairments resulting from traumatic brain injury for purposes of awarding disability compensation. This report also provides recommendations for legislative or administrative action for improving the adjudication of veterans' claims seeking entitlement to compensation for all impairments arising from a traumatic brain injury.

Pain

Pain PDF Author:
Publisher:
ISBN:
Category : Chronically ill
Languages : en
Pages : 58

Get Book Here

Book Description


Disease Control Priorities, Third Edition (Volume 4)

Disease Control Priorities, Third Edition (Volume 4) PDF Author: Vikram Patel
Publisher: World Bank Publications
ISBN: 1464804281
Category : Medical
Languages : en
Pages : 307

Get Book Here

Book Description
Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.

Disease and Mortality in Sub-Saharan Africa

Disease and Mortality in Sub-Saharan Africa PDF Author: Dean T. Jamison
Publisher: World Bank Publications
ISBN: 0821363980
Category : Medical
Languages : en
Pages : 414

Get Book Here

Book Description
Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.

Epilepsy Across the Spectrum

Epilepsy Across the Spectrum PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309259533
Category : Medical
Languages : en
Pages : 568

Get Book Here

Book Description
Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.

Mind, Brain, Body, and Behavior

Mind, Brain, Body, and Behavior PDF Author: Ingrid G. Farreras
Publisher: IOS Press
ISBN: 9781586034719
Category : Mental health
Languages : en
Pages : 404

Get Book Here

Book Description
Provides insights not only into the work of the National Institutes of Health, but the relationship between institutional and governmental structures and the manner in which they influenced the direction taken by individual scientists. The recollections of the individuals in the intramural program juxtaposed alongside whatever primary sources have survived also provide an equally fascinating contrast. It provides a perspective that can illuminate contemporary policy debates about the nature and direction of biomedical and social science research as well as the relationships between government and science.

Improving the Utility and Translation of Animal Models for Nervous System Disorders

Improving the Utility and Translation of Animal Models for Nervous System Disorders PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309266335
Category : Medical
Languages : en
Pages : 111

Get Book Here

Book Description
Nervous system diseases and disorders are highly prevalent and substantially contribute to the overall disease burden. Despite significant information provided by the use of animal models in the understanding of the biology of nervous system disorders and the development of therapeutics; limitations have also been identified. Treatment options that are high in efficacy and low in side effects are still lacking for many diseases and, in some cases are nonexistent. A particular problem in drug development is the high rate of attrition in Phase II and III clinical trials. Why do many therapeutics show promise in preclinical animal models but then fail to elicit predicted effects when tested in humans? On March 28 and 29, 2012, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened the workshop "Improving Translation of Animal Models for Nervous System Disorders" to discuss potential opportunities for maximizing the translation of new therapies from animal models to clinical practice. The primary focus of the workshop was to examine mechanisms for increasing the efficiency of translational neuroscience research through discussions about how and when to use animal models most effectively and then best approaches for the interpretation of the data collected. Specifically, the workshop objectives were to: discuss key issues that contribute to poor translation of animal models in nervous system disorders, examine case studies that highlight successes and failures in the development and application of animal models, consider strategies to increase the scientific rigor of preclinical efficacy testing, explore the benefits and challenges to developing standardized animal and behavioral models. Improving the Utility and Translation of Animal Models for Nervous System Disorders: Workshop Summary also identifies methods to facilitate development of corresponding animal and clinical endpoints, indentifies methods that would maximize bidirectional translation between basic and clinical research and determines the next steps that will be critical for improvement of the development and testing of animal models of disorders of the nervous system.

Concussion Care Manual

Concussion Care Manual PDF Author: David L. Brody MD
Publisher: Oxford University Press
ISBN: 0190054816
Category : Medical
Languages : en
Pages : 257

Get Book Here

Book Description
It is hard to find a medical condition that has as much media attention as concussion. With growing interest in concussion care by the NFL, NHL, NBA, and many other sports organizations, the military, and by regular patients, the number of concussion care providers has rapidly increased. Concussion Care Manual, Second Edition is the perfect step-by-step concussion management guide for clinicians, coaches, and even parents of athletic children. This pocket-sized volume discusses how to manage a variety of complexities associated with concussions including proper diagnosis, management strategies, headaches, anxiety and depression, PTSD, dizziness, fatigue, and changes to mood, balance, personality, and sleep. This book also covers the essential elements on how to set up and run a concussion clinic, focusing on the administrative need-to-know. A much-needed list of references, scales, and resources are provided at the end of the book for further investigation. New to the Second Edition… -Fully revised based on the most up-to-date research in the field across disciplines - Evidence-based, this new edition summarizes what works and what doesn't from recent clinical trials and real world concussion care experience -Provides step by step guidance on how to provide appropriate active management when treating concussion