Author: Richard J Cook
Publisher: CRC Press
ISBN: 1351646052
Category : Mathematics
Languages : en
Pages : 500
Book Description
Multistate Models for the Analysis of Life History Data provides the first comprehensive treatment of multistate modeling and analysis, including parametric, nonparametric and semiparametric methods applicable to many types of life history data. Special models such as illness-death, competing risks and progressive processes are considered, as well as more complex models. The book provides both theoretical development and illustrations of analysis based on data from randomized trials and observational cohort studies in health research. It features: Discusses a wide range of applications of multistate models, Presents methods for both continuously and intermittently observed life history processes, Gives a thorough discussion of conditionally independent censoring and observation processes, Discusses models with random effects and joint models for two or more multistate processes, Discusses and illustrates software for multistate analysis that is available in R, Target audience includes those engaged in research and applications involving multistate models.
Multistate Models for the Analysis of Life History Data
Author: Richard J Cook
Publisher: CRC Press
ISBN: 1351646052
Category : Mathematics
Languages : en
Pages : 500
Book Description
Multistate Models for the Analysis of Life History Data provides the first comprehensive treatment of multistate modeling and analysis, including parametric, nonparametric and semiparametric methods applicable to many types of life history data. Special models such as illness-death, competing risks and progressive processes are considered, as well as more complex models. The book provides both theoretical development and illustrations of analysis based on data from randomized trials and observational cohort studies in health research. It features: Discusses a wide range of applications of multistate models, Presents methods for both continuously and intermittently observed life history processes, Gives a thorough discussion of conditionally independent censoring and observation processes, Discusses models with random effects and joint models for two or more multistate processes, Discusses and illustrates software for multistate analysis that is available in R, Target audience includes those engaged in research and applications involving multistate models.
Publisher: CRC Press
ISBN: 1351646052
Category : Mathematics
Languages : en
Pages : 500
Book Description
Multistate Models for the Analysis of Life History Data provides the first comprehensive treatment of multistate modeling and analysis, including parametric, nonparametric and semiparametric methods applicable to many types of life history data. Special models such as illness-death, competing risks and progressive processes are considered, as well as more complex models. The book provides both theoretical development and illustrations of analysis based on data from randomized trials and observational cohort studies in health research. It features: Discusses a wide range of applications of multistate models, Presents methods for both continuously and intermittently observed life history processes, Gives a thorough discussion of conditionally independent censoring and observation processes, Discusses models with random effects and joint models for two or more multistate processes, Discusses and illustrates software for multistate analysis that is available in R, Target audience includes those engaged in research and applications involving multistate models.
Multistate Analysis of Life Histories with R
Author: Frans Willekens
Publisher: Springer
ISBN: 331908383X
Category : Mathematics
Languages : en
Pages : 323
Book Description
This book provides an introduction to multistate event history analysis. It is an extension of survival analysis, in which a single terminal event (endpoint) is considered and the time-to-event is studied. Multistate models focus on life histories or trajectories, conceptualized as sequences of states and sequences of transitions between states. Life histories are modeled as realizations of continuous-time Markov processes. The model parameters, transition rates, are estimated from data on event counts and populations at risk, using the statistical theory of counting processes. The Comprehensive R Network Archive (CRAN) includes several packages for multistate modeling. This book is about Biograph. The package is designed to (a) enhance exploratory analysis of life histories and (b) make multistate modeling accessible. The package incorporates utilities that connect to several packages for multistate modeling, including survival, eha, Epi, mvna,, mstate, msm, and TraMineR for sequence analysis. The book is a ‘hands-on’ presentation of Biograph and the packages listed. It is written from the perspective of the user. To help the user master the techniques and the software, a single data set is used to illustrate the methods and software. It is the subsample of the German Life History Survey, which was also used by Blossfeld and Rohwer in their popular textbook on event history modeling. Another data set, the Netherlands Family and Fertility Survey, is used to illustrate how Biograph can assist in answering questions on life paths of cohorts and individuals. The book is suitable as a textbook for graduate courses on event history analysis and introductory courses on competing risks and multistate models. It may also be used as a self-study book. The R code used in the book is available online. Frans Willekens is affiliated with the Max Planck Institute for Demographic Research (MPIDR) in Rostock, Germany. He is Emeritus Professor of Demography at the University of Groningen, a Honorary Fellow of the Netherlands Interdisciplinary Demographic Institute (NIDI) in the Hague, and a Research Associate of the International Institute for Applied Systems Analysis (IIASA), Laxenburg, Austria. He is a member of Royal Netherlands Academy of Arts and Sciences (KNAW). He has contributed to the modeling and simulation of life histories, mainly in the context of population forecasting.
Publisher: Springer
ISBN: 331908383X
Category : Mathematics
Languages : en
Pages : 323
Book Description
This book provides an introduction to multistate event history analysis. It is an extension of survival analysis, in which a single terminal event (endpoint) is considered and the time-to-event is studied. Multistate models focus on life histories or trajectories, conceptualized as sequences of states and sequences of transitions between states. Life histories are modeled as realizations of continuous-time Markov processes. The model parameters, transition rates, are estimated from data on event counts and populations at risk, using the statistical theory of counting processes. The Comprehensive R Network Archive (CRAN) includes several packages for multistate modeling. This book is about Biograph. The package is designed to (a) enhance exploratory analysis of life histories and (b) make multistate modeling accessible. The package incorporates utilities that connect to several packages for multistate modeling, including survival, eha, Epi, mvna,, mstate, msm, and TraMineR for sequence analysis. The book is a ‘hands-on’ presentation of Biograph and the packages listed. It is written from the perspective of the user. To help the user master the techniques and the software, a single data set is used to illustrate the methods and software. It is the subsample of the German Life History Survey, which was also used by Blossfeld and Rohwer in their popular textbook on event history modeling. Another data set, the Netherlands Family and Fertility Survey, is used to illustrate how Biograph can assist in answering questions on life paths of cohorts and individuals. The book is suitable as a textbook for graduate courses on event history analysis and introductory courses on competing risks and multistate models. It may also be used as a self-study book. The R code used in the book is available online. Frans Willekens is affiliated with the Max Planck Institute for Demographic Research (MPIDR) in Rostock, Germany. He is Emeritus Professor of Demography at the University of Groningen, a Honorary Fellow of the Netherlands Interdisciplinary Demographic Institute (NIDI) in the Hague, and a Research Associate of the International Institute for Applied Systems Analysis (IIASA), Laxenburg, Austria. He is a member of Royal Netherlands Academy of Arts and Sciences (KNAW). He has contributed to the modeling and simulation of life histories, mainly in the context of population forecasting.
Competing Risks and Multistate Models with R
Author: Jan Beyersmann
Publisher: Springer Science & Business Media
ISBN: 1461420350
Category : Mathematics
Languages : en
Pages : 249
Book Description
This book covers competing risks and multistate models, sometimes summarized as event history analysis. These models generalize the analysis of time to a single event (survival analysis) to analysing the timing of distinct terminal events (competing risks) and possible intermediate events (multistate models). Both R and multistate methods are promoted with a focus on nonparametric methods.
Publisher: Springer Science & Business Media
ISBN: 1461420350
Category : Mathematics
Languages : en
Pages : 249
Book Description
This book covers competing risks and multistate models, sometimes summarized as event history analysis. These models generalize the analysis of time to a single event (survival analysis) to analysing the timing of distinct terminal events (competing risks) and possible intermediate events (multistate models). Both R and multistate methods are promoted with a focus on nonparametric methods.
Multistate Models for the Analysis of Life History Data
Author: Richard J Cook
Publisher: CRC Press
ISBN: 1498715613
Category : Mathematics
Languages : en
Pages : 441
Book Description
Multistate Models for the Analysis of Life History Data provides the first comprehensive treatment of multistate modeling and analysis, including parametric, nonparametric and semiparametric methods applicable to many types of life history data. Special models such as illness-death, competing risks and progressive processes are considered, as well as more complex models. The book provides both theoretical development and illustrations of analysis based on data from randomized trials and observational cohort studies in health research. It features: Discusses a wide range of applications of multistate models, Presents methods for both continuously and intermittently observed life history processes, Gives a thorough discussion of conditionally independent censoring and observation processes, Discusses models with random effects and joint models for two or more multistate processes, Discusses and illustrates software for multistate analysis that is available in R, Target audience includes those engaged in research and applications involving multistate models.
Publisher: CRC Press
ISBN: 1498715613
Category : Mathematics
Languages : en
Pages : 441
Book Description
Multistate Models for the Analysis of Life History Data provides the first comprehensive treatment of multistate modeling and analysis, including parametric, nonparametric and semiparametric methods applicable to many types of life history data. Special models such as illness-death, competing risks and progressive processes are considered, as well as more complex models. The book provides both theoretical development and illustrations of analysis based on data from randomized trials and observational cohort studies in health research. It features: Discusses a wide range of applications of multistate models, Presents methods for both continuously and intermittently observed life history processes, Gives a thorough discussion of conditionally independent censoring and observation processes, Discusses models with random effects and joint models for two or more multistate processes, Discusses and illustrates software for multistate analysis that is available in R, Target audience includes those engaged in research and applications involving multistate models.
Introducing Survival and Event History Analysis
Author: Melinda Mills
Publisher: SAGE
ISBN: 1848601026
Category : Social Science
Languages : en
Pages : 301
Book Description
This book is an accessible, practical and comprehensive guide for researchers from multiple disciplines including biomedical, epidemiology, engineering and the social sciences. Written for accessibility, this book will appeal to students and researchers who want to understand the basics of survival and event history analysis and apply these methods without getting entangled in mathematical and theoretical technicalities. Inside, readers are offered a blueprint for their entire research project from data preparation to model selection and diagnostics. Engaging, easy to read, functional and packed with enlightening examples, ‘hands-on’ exercises, conversations with key scholars and resources for both students and instructors, this text allows researchers to quickly master advanced statistical techniques. It is written from the perspective of the ‘user’, making it suitable as both a self-learning tool and graduate-level textbook. Also included are up-to-date innovations in the field, including advancements in the assessment of model fit, unobserved heterogeneity, recurrent events and multilevel event history models. Practical instructions are also included for using the statistical programs of R, STATA and SPSS, enabling readers to replicate the examples described in the text.
Publisher: SAGE
ISBN: 1848601026
Category : Social Science
Languages : en
Pages : 301
Book Description
This book is an accessible, practical and comprehensive guide for researchers from multiple disciplines including biomedical, epidemiology, engineering and the social sciences. Written for accessibility, this book will appeal to students and researchers who want to understand the basics of survival and event history analysis and apply these methods without getting entangled in mathematical and theoretical technicalities. Inside, readers are offered a blueprint for their entire research project from data preparation to model selection and diagnostics. Engaging, easy to read, functional and packed with enlightening examples, ‘hands-on’ exercises, conversations with key scholars and resources for both students and instructors, this text allows researchers to quickly master advanced statistical techniques. It is written from the perspective of the ‘user’, making it suitable as both a self-learning tool and graduate-level textbook. Also included are up-to-date innovations in the field, including advancements in the assessment of model fit, unobserved heterogeneity, recurrent events and multilevel event history models. Practical instructions are also included for using the statistical programs of R, STATA and SPSS, enabling readers to replicate the examples described in the text.
Multi-State Survival Models for Interval-Censored Data
Author: Ardo van den Hout
Publisher: CRC Press
ISBN: 1315356732
Category : Mathematics
Languages : en
Pages : 323
Book Description
Multi-State Survival Models for Interval-Censored Data introduces methods to describe stochastic processes that consist of transitions between states over time. It is targeted at researchers in medical statistics, epidemiology, demography, and social statistics. One of the applications in the book is a three-state process for dementia and survival in the older population. This process is described by an illness-death model with a dementia-free state, a dementia state, and a dead state. Statistical modelling of a multi-state process can investigate potential associations between the risk of moving to the next state and variables such as age, gender, or education. A model can also be used to predict the multi-state process. The methods are for longitudinal data subject to interval censoring. Depending on the definition of a state, it is possible that the time of the transition into a state is not observed exactly. However, when longitudinal data are available the transition time may be known to lie in the time interval defined by two successive observations. Such an interval-censored observation scheme can be taken into account in the statistical inference. Multi-state modelling is an elegant combination of statistical inference and the theory of stochastic processes. Multi-State Survival Models for Interval-Censored Data shows that the statistical modelling is versatile and allows for a wide range of applications.
Publisher: CRC Press
ISBN: 1315356732
Category : Mathematics
Languages : en
Pages : 323
Book Description
Multi-State Survival Models for Interval-Censored Data introduces methods to describe stochastic processes that consist of transitions between states over time. It is targeted at researchers in medical statistics, epidemiology, demography, and social statistics. One of the applications in the book is a three-state process for dementia and survival in the older population. This process is described by an illness-death model with a dementia-free state, a dementia state, and a dead state. Statistical modelling of a multi-state process can investigate potential associations between the risk of moving to the next state and variables such as age, gender, or education. A model can also be used to predict the multi-state process. The methods are for longitudinal data subject to interval censoring. Depending on the definition of a state, it is possible that the time of the transition into a state is not observed exactly. However, when longitudinal data are available the transition time may be known to lie in the time interval defined by two successive observations. Such an interval-censored observation scheme can be taken into account in the statistical inference. Multi-state modelling is an elegant combination of statistical inference and the theory of stochastic processes. Multi-State Survival Models for Interval-Censored Data shows that the statistical modelling is versatile and allows for a wide range of applications.
Nonparametric Models for Longitudinal Data
Author: Colin O. Wu
Publisher: CRC Press
ISBN: 0429939086
Category : Mathematics
Languages : en
Pages : 583
Book Description
Nonparametric Models for Longitudinal Data with Implementations in R presents a comprehensive summary of major advances in nonparametric models and smoothing methods with longitudinal data. It covers methods, theories, and applications that are particularly useful for biomedical studies in the era of big data and precision medicine. It also provides flexible tools to describe the temporal trends, covariate effects and correlation structures of repeated measurements in longitudinal data. This book is intended for graduate students in statistics, data scientists and statisticians in biomedical sciences and public health. As experts in this area, the authors present extensive materials that are balanced between theoretical and practical topics. The statistical applications in real-life examples lead into meaningful interpretations and inferences. Features: • Provides an overview of parametric and semiparametric methods • Shows smoothing methods for unstructured nonparametric models • Covers structured nonparametric models with time-varying coefficients • Discusses nonparametric shared-parameter and mixed-effects models • Presents nonparametric models for conditional distributions and functionals • Illustrates implementations using R software packages • Includes datasets and code in the authors’ website • Contains asymptotic results and theoretical derivations
Publisher: CRC Press
ISBN: 0429939086
Category : Mathematics
Languages : en
Pages : 583
Book Description
Nonparametric Models for Longitudinal Data with Implementations in R presents a comprehensive summary of major advances in nonparametric models and smoothing methods with longitudinal data. It covers methods, theories, and applications that are particularly useful for biomedical studies in the era of big data and precision medicine. It also provides flexible tools to describe the temporal trends, covariate effects and correlation structures of repeated measurements in longitudinal data. This book is intended for graduate students in statistics, data scientists and statisticians in biomedical sciences and public health. As experts in this area, the authors present extensive materials that are balanced between theoretical and practical topics. The statistical applications in real-life examples lead into meaningful interpretations and inferences. Features: • Provides an overview of parametric and semiparametric methods • Shows smoothing methods for unstructured nonparametric models • Covers structured nonparametric models with time-varying coefficients • Discusses nonparametric shared-parameter and mixed-effects models • Presents nonparametric models for conditional distributions and functionals • Illustrates implementations using R software packages • Includes datasets and code in the authors’ website • Contains asymptotic results and theoretical derivations
The Statistical Analysis of Failure Time Data
Author: John D. Kalbfleisch
Publisher: John Wiley & Sons
ISBN: 1118031237
Category : Mathematics
Languages : en
Pages : 462
Book Description
Contains additional discussion and examples on left truncationas well as material on more general censoring and truncationpatterns. Introduces the martingale and counting process formulation swillbe in a new chapter. Develops multivariate failure time data in a separate chapterand extends the material on Markov and semi Markovformulations. Presents new examples and applications of data analysis.
Publisher: John Wiley & Sons
ISBN: 1118031237
Category : Mathematics
Languages : en
Pages : 462
Book Description
Contains additional discussion and examples on left truncationas well as material on more general censoring and truncationpatterns. Introduces the martingale and counting process formulation swillbe in a new chapter. Develops multivariate failure time data in a separate chapterand extends the material on Markov and semi Markovformulations. Presents new examples and applications of data analysis.
The Statistical Analysis of Recurrent Events
Author: Richard J. Cook
Publisher: Springer Science & Business Media
ISBN: 0387698094
Category : Medical
Languages : en
Pages : 415
Book Description
This book presents models and statistical methods for the analysis of recurrent event data. The authors provide broad, detailed coverage of the major approaches to analysis, while emphasizing the modeling assumptions that they are based on. More general intensity-based models are also considered, as well as simpler models that focus on rate or mean functions. Parametric, nonparametric and semiparametric methodologies are all covered, with procedures for estimation, testing and model checking.
Publisher: Springer Science & Business Media
ISBN: 0387698094
Category : Medical
Languages : en
Pages : 415
Book Description
This book presents models and statistical methods for the analysis of recurrent event data. The authors provide broad, detailed coverage of the major approaches to analysis, while emphasizing the modeling assumptions that they are based on. More general intensity-based models are also considered, as well as simpler models that focus on rate or mean functions. Parametric, nonparametric and semiparametric methodologies are all covered, with procedures for estimation, testing and model checking.
Analysis of Multivariate Survival Data
Author: Philip Hougaard
Publisher: Springer Science & Business Media
ISBN: 1461213045
Category : Mathematics
Languages : en
Pages : 559
Book Description
Survival data or more general time-to-event data occur in many areas, including medicine, biology, engineering, economics, and demography, but previously standard methods have requested that all time variables are univariate and independent. This book extends the field by allowing for multivariate times. As the field is rather new, the concepts and the possible types of data are described in detail. Four different approaches to the analysis of such data are presented from an applied point of view.
Publisher: Springer Science & Business Media
ISBN: 1461213045
Category : Mathematics
Languages : en
Pages : 559
Book Description
Survival data or more general time-to-event data occur in many areas, including medicine, biology, engineering, economics, and demography, but previously standard methods have requested that all time variables are univariate and independent. This book extends the field by allowing for multivariate times. As the field is rather new, the concepts and the possible types of data are described in detail. Four different approaches to the analysis of such data are presented from an applied point of view.