Neurocytochemical Methods PDF Download
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Author: Andre Calas
Publisher: Springer Science & Business Media
ISBN: 3642842984
Category : Medical
Languages : en
Pages : 336
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Book Description
The great strides made in the field of morphological methods during the past decades have perhaps found their most spectacular expression in the functional exploration of the nervous system. In comparison with other tissues, nerve tissue displays three kinds of specificity : structural, because of the unique organization of the neuronal networks ; chemical as shown, for example, by the informative molecules exchanged between the nerve cells, and of course functional, thanks to the particular metabolic and electrophysiological characteristics of the neurons. Although for a long time the structural properties of the nervous system were generally considered to constitute the only field to which morphological techniques could be applied, we are to-day justified in believing that they can also explore the nerve tissue through its specific chemical and functional aspects, thanks to the development of immunocytochemistry and in situ hybridization, to the elaboration of the deoxyglucose method, to the use of voltage or ion sensitive dyes, and to the progress made in the application of in vivo techniques like PET. These methods have evolved so fast, the technical and fundamental problems they raise are so numerous and stimulating, and the importance of the complementary data they provide is so obvious, that we thought it was a good time to organize a new meeting between distinguished specialists in the neurocytochemical field.
Author: Hannsjörg Schröder
Publisher: Springer Nature
ISBN: 3030198987
Category : Medical
Languages : en
Pages : 353
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Book Description
This textbook describes the basic neuroanatomy of the laboratory mouse. The reader will be guided through the anatomy of the mouse nervous system with the help of abundant microphotographs and schemata. Learning objectives and summaries of key facts at the beginning of each chapter provide the reader with an overview on the most important information. As transgenic mice are one of the most widely used paradigms when it comes to modeling human diseases, a basic understanding of the neuroanatomy of the mouse is of considerable value for all students and researchers in the neurosciences and pharmacy, but also in human and veterinary medicine. Accordingly, the authors have included, whenever possible, comparisons of the murine and the human nervous system. The book is intended as a guide for all those who are about to embark on the structural, histochemical and functional phenotyping of the mouse’s central nervous system. It can serve as a practical handbook for students and early researchers, and as a reference book for neuroscience lectures and laboratories.
Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485
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Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Author: Jeffery A. Winer
Publisher: Springer Science & Business Media
ISBN: 0387270833
Category : Science
Languages : en
Pages : 720
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Book Description
Connecting the auditory brain stem to sensory, motor, and limbic systems, the inferior colliculus is a critical midbrain station for auditory processing. Winer and Schreiner's The Inferior Colliculus, a critical, comprehensive reference, presents the current knowledge of the inferior colliculus from a variety of perspectives, including anatomical, physiological, developmental, neurochemical, biophysical, neuroethological and clinical vantage points. Written by leading researchers in the field, the book is an ideal introduction to the inferior colliculus and central auditory processing for clinicians, otolaryngologists, graduate and postgraduate research workers in the auditory and other sensory-motor systems.
Author: John Harry Martin
Publisher: McGraw Hill Professional
ISBN: 9780071381833
Category : Medical
Languages : en
Pages : 566
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Book Description
With over 400 illustrations, this thoroughly updated edition examines how parts of the nervous system work together to regulate body systems and produce behavior.
Author: C. U. M. Smith
Publisher: John Wiley & Sons
ISBN: 047085717X
Category : Medical
Languages : en
Pages : 630
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Book Description
This edition of the popular text incorporates recent advances in neurobiology enabled by modern molecular biology techniques. Understanding how the brain works from a molecular level allows research to better understand behaviours, cognition, and neuropathologies. Since the appearance six years ago of the second edition, much more has been learned about the molecular biology of development and its relations with early evolution. This "evodevo" (as it has come to be known) framework also has a great deal of bearing on our understanding of neuropathologies as dysfunction of early onset genes can cause neurodegeneration in later life. Advances in our understanding of the genomes and proteomes of a number of organisms also greatly influence our understanding of neurobiology. * Well known and widely used as a text throughout the UK, good reviews from students and lecturers. * Good complement to Fundementals of Psychopharmacology by Brian Leonard. This book will be of particular interest to biomedical undergraduates undertaking a neuroscience unit, neuroscience postgraduates, physiologists, pharmacologists. It is also a useful basic reference for university libraries. Maurice Elphick, Queen Mary, University of London "I do like this book and it is the recommended textbook for my course in Molecular Neuroscience. The major strength of the book is the overall simplicity of the format both in terms of layout and diagrams."
Author: Charles Watson
Publisher: Academic Press
ISBN: 0123694973
Category : Medical
Languages : en
Pages : 815
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Book Description
The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness
Author: David L. Felten
Publisher: Elsevier Health Sciences
ISBN: 0323265111
Category : Medical
Languages : en
Pages : 499
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Book Description
Ideal for students of neuroscience and neuroanatomy, the new edition of Netter's Atlas of Neuroscience combines the didactic well-loved illustrations of Dr. Frank Netter with succinct text and clinical points, providing a highly visual, clinically oriented guide to the most important topics in this subject. The logically organized content presents neuroscience from three perspectives: an overview of the nervous system, regional neuroscience, and systemic neuroscience, enabling you to review complex neural structures and systems from different contexts. You may also be interested in: A companion set of flash cards, Netter's Neuroscience Flash Cards, 3rd Edition, to which the textbook is cross-referenced. Coverage of both regional and systemic neurosciences allows you to learn structure and function in different and important contexts. Combines the precision and beauty of Netter and Netter-style illustrations to highlight key neuroanatomical concepts and clinical correlations. Reflects the current understanding of the neural components and supportive tissue, regions, and systems of the brain, spinal cord, and periphery. Uniquely informative drawings provide a quick and memorable overview of anatomy, function, and clinical relevance. Succinct and useful format utilizes tables and short text to offer easily accessible "at-a-glance" information. Provides an overview of the basic features of the spinal cord, brain, and peripheral nervous system, the vasculature, meninges and cerebrospinal fluid, and basic development. Integrates the peripheral and central aspects of the nervous system. Bridges neuroanatomy and neurology through the use of correlative radiographs. Highlights cross-sectional brain stem anatomy and side-by-side comparisons of horizontal sections, CTs and MRIs. Features video of radiograph sequences and 3D reconstructions to enhance your understanding of the nervous system. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, 14 videos, and images from the book. Expanded coverage of cellular and molecular neuroscience provides essential guidance on signaling, transcription factors, stem cells, evoked potentials, neuronal and glial function, and a number of molecular breakthroughs for a better understanding of normal and pathologic conditions of the nervous system. Micrographs, radiologic imaging, and stained cross sections supplement illustrations for a comprehensive visual understanding. Increased clinical points -- from sleep disorders and inflammation in the CNS to the biology of seizures and the mechanisms of Alzheimer's -- offer concise insights that bridge basic neuroscience and clinical application.
Author: Marco Catani
Publisher: Oxford University Press, USA
ISBN: 0199541167
Category : Medical
Languages : en
Pages : 533
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Book Description
One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour. This atlas capitalises on novel diffusion MRI tractography methods to provide a comprehensive overview of connections derived from virtual in vivo tractography dissections of the human brain.
Author: Valery Grinevich
Publisher: Springer
ISBN: 9783030866327
Category : Medical
Languages : en
Pages : 0
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Book Description
In this book, experts in the field provide comprehensive descriptions of the neuroanatomy of the hypothalamic neuroendocrine systems. The book begins with an extensive discussion on the structural components of the neuroendocrine systems. The reader will be introduced to the anatomy and biology of the hypothalamus and the pituitary. The human hypothalamus is presented in particular detail using state-of-the-art imaging techniques. In the next section, the neuroanatomy of traditional hypothalamo-hypophyseal systems is highlighted, with chapters describing magnocellular neuroendocrine cells and discussing the respective types of hypothalamic neurons that regulate various pituitary hormones. Following this detailed structural and anatomical description of the neuroendocrine system, the book’s final section focuses on the hypothalamic control of neuroendocrine functions. This includes the control of circadian rhythm, metabolism and appetite via specific peptidergic circuits. This book provides essential information on the neuroanatomy and control of neuroendocrine systems, addresses cutting-edge research questions posed by recent advances in the development of potent neuroanatomical tools, and highlights the latest technologies used in neuroendocrinology research, making it a valuable reference guide for students, trainees and established researchers alike. This is the twelfth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and to encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. Chapter 12 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com
Author: Joseph J. Warner
Publisher: Butterworth-Heinemann
ISBN:
Category : Medical
Languages : en
Pages : 702
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Book Description
* Contains one of the best collections of neural images to appear in an atlas * Included throughout are high-resolution slide images of gross brain and spinal cord anatomy and histologic preparations * Places major emphasis on functional correlations and principles of systems organizations
