Molecular Mechanisms of Synaptic Vesicle Exocytosis PDF Download
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Author: K. Hu
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: K. Hu
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Zhao-Wen Wang
Publisher: Springer Science & Business Media
ISBN: 1597454818
Category : Medical
Languages : en
Pages : 354
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Book Description
Neurons in the nervous system organize into complex networks and their functions are precisely controlled. The most important means for neurons to communicate with each other is transmission through chemical synapses, where the release of neurotransmitters by the presynaptic nerve terminal of one neuron influences the function of a second neuron. Since the discovery of chemical neurotransmission by Otto Loewi in the 1920s, great progress has been made in our understanding of mol- ular mechanisms of neurotransmitter release. The last decade has seen an explosion of knowledge in this field. The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release. The contributors have made great efforts to write concisely but with sufficient background information, and to use figures/diagrams to present clearly key concepts or experiments. It is hoped that this book may serve as a learning tool for neuroscience students, a solid reference for neuroscientists, and a source of knowledge for people who have a general interest in neuroscience. I was fortunate to be able to gather contributions from a group of outstanding scientists. I thank them for their efforts. In particular, I want to thank Dr. Erik Jorgensen who offered valuable suggestions about the book in addition to contrib- ing an excellent chapter. I thank US National Science Foundation and National Institute of Health for their supports.
Author: Robby M. Weimer
Publisher:
ISBN:
Category : Caenorhabditis elegans
Languages : en
Pages : 358
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Book Description
Author: Romano Regazzi
Publisher: Springer Science & Business Media
ISBN: 0387399615
Category : Science
Languages : en
Pages : 186
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Book Description
This book examines the role of key components in the exocytotic process, not only in neuronal and endocrine cells but in a variety of other relevant cell systems. So far, because of the large number of components involved, understanding of the molecular basis of exocytosis has remained the privilege of a relatively small group of specialists. The book collects up-to-date reviews from the forefront of this fascinating and rapidly evolving field.
Author: Jiajie Diao
Publisher: Frontiers Media SA
ISBN: 2889636925
Category :
Languages : en
Pages : 252
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Book Description
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Author: Sindhuja Gowrisankaran
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Synaptic vesicle (SV) recycling at the synapse is fundamental to neurotransmission and it sustains unimpaired neuronal communication. It is a complex cell biological process, where the molecular steps are finely coordinated and intensively studied in the last three decades. The basic principles and the regulatory mechanisms underlying key steps like exocytosis and endocytosis have been broadly understood. Yet, there are several missing links in SV recycling process. Some of the open questions that are not well understood include the mechanism of how exocytosis is coupled with endocytic retr...
Author: Zhao-Wen Wang
Publisher: Springer Nature
ISBN: 3031342291
Category : Medical
Languages : en
Pages : 408
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Book Description
Neurons communicate with each other by releasing neurotransmitters. This book provides comprehensive coverage of the molecular mechanisms involved in neurotransmitter release. The topics covered in the book range from the architecture and cytomatrix proteins of presynaptic sites, to the modes of synaptic vesicle exocytosis (full-collapse and kiss-and-run), and from the key molecules mediating synaptic vesicle fusion (SNAREs) to those that closely interact with them (UNC-13/Munc13, UNC-18/Munc18, tomosyn, and complexins). The book also delves into the calcium sensors of synaptic vesicle fusion (synaptotagmins and Doc2s), the sources of calcium that trigger synaptic exocytosis (voltage-gated calcium channels and ryanodine receptors), and the regulation of neurotransmitter release by potassium channels, cell adhesion molecules, lipids, aryl hydrocarbon receptor-interacting protein (AIP), presenilins, and calstabins. To aid in understanding and illustrate key concepts, the book includes sufficient background information and a wealth of illustrations and diagrams. The new edition includes major updates to previous chapters, as well as several new chapters that reflect the recent advances in the field. Comprehensive and cutting-edge, Molecular Mechanisms of Neurotransmitter Release, 2nd edition, is a valuable learning resource for neuroscience students and a solid reference for neuroscientists.
Author: Alexander Dityatev
Publisher: Springer Science & Business Media
ISBN: 038732562X
Category : Medical
Languages : en
Pages : 504
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Book Description
This book provides a new compilation of information that link changes in the basic structure of synapses and brain diseases. The book shows that specific secreted proteins, and short peptide mimicking the function of neural cell adhesion molecules can significantly enhance the formation of synapses in the brain. It describes recent advances in research that lay necessary scientific groundwork to develop pharmacological treatments.
Author: Hugo J. Bellen
Publisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 466
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Book Description
This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.
