Molecular Genetics of Hypertension and Related Traits PDF Download
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Author: Markus Perola
Publisher:
ISBN: 9789517401241
Category :
Languages : en
Pages : 90
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Book Description
Author: Markus Perola
Publisher:
ISBN: 9789517401241
Category :
Languages : en
Pages : 90
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Book Description
Author: Anna F. Dominiczak
Publisher: Elsevier Health Sciences
ISBN: 0444514562
Category : Medical
Languages : en
Pages : 284
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Book Description
Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.
Author: Madhu Khullar
Publisher: BoD – Books on Demand
ISBN: 9535102826
Category : Medical
Languages : en
Pages : 250
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Book Description
This book, authored by renowned researchers in the field of Hypertension Research, details the state of the art knowledge in genetics, genomics and pathophysiology of Essential hypertension, specifically the genetic determinants of hypertension and role of gene variants in response to anti-hypertensive therapy. Two chapters describe mitochondrial mutations in Essential hypertension and in hypertension associated Left ventricular hypertrophy, one chapter reviews in detail the global gene expression in hypertension, and an up to date treatise on pathophysiology of resistant hypertension is detailed in another chapter. Other topics included in the book are end organ damage, baroreceptor sensitivity and role of music therapy in essential hypertension.
Author: A. F. Dominiczak
Publisher: Garland Science
ISBN: 9781859961025
Category : Medical
Languages : en
Pages : 292
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Book Description
Molecular Genetics of Hypertension is a comprehensive and up-to-date assessment of our current knowledge of this disease. Written and edited by leaders in the field, it highlights both the latest research data and the clinical implications of these findings. The book provides essential information for both clinicians and researchers in this multidisciplinary field.
Author: P. M. Frossard
Publisher: VSP
ISBN: 9789067643115
Category : Medical
Languages : en
Pages : 284
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Book Description
Author: Wybren de Jong
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 664
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Book Description
Hardbound. This volume is a worthy successor to volume 4 by virtue of its focus on the recent conceptual revolution in fundamental hypertension research. Without neglecting the heritage of earlier achievements, it highlights such brilliant breakthroughs in molecular genetics as the creation of transgenic animals as a source of a new pathogenesis of hypertension.A core of (patho)physiological mechanisms operative in experimental hypertension is provided, including several which act to maintain a normotensive state. The volume provides background and technical information on the use of different models of hypertension in a variety of animal species. A wealth of new information regarding the several different complications observed in genetic and other models of hypertension, as well as new animal models dedicated to these aspects, are also presented. Furthermore, new chapters addressing genotyping and the use of transgenics in hypertension are included.
Author: F. Soubrier
Publisher: R. G. Landes
ISBN: 9780412130816
Category : Medical
Languages : en
Pages : 250
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Book Description
Author: Ruby Ching-Yu Lin
Publisher:
ISBN:
Category : Gene expression
Languages : en
Pages : 300
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Book Description
Author: Xi Cheng
Publisher: Biota Publishing
ISBN: 161504695X
Category : Medical
Languages : en
Pages : 67
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Book Description
Hypertension, or elevated blood pressure, is a major risk factor for various cardiovascular, renal diseases, and stroke. The form of hypertension with no identifiable cause is referred to as Essential Hypertension. Familial studies indicate that Essential Hypertension is heritable and, thereby, classical genetic approaches have been applied on both human and other mammalian models of hypertension to map the locations of the allelic variants within quantitative trait loci for blood pressure. The post genome era has further elevated this area of research into large-scale genome-wide association studies of hypertension in humans. Collectively, these studies have resulted in the prioritization and cataloging of several genomic regions containing allelic variants as candidates linked or associated with essential hypertension. Further, they are providing evidence to suggest that the inheritance of hypertension is rather complex, encompassing multiple variants both within protein-coding and non-coding annotations, each of which may act independently or interactively with other genes and/or environmental factors to differentially regulate blood pressure. This book provides an overview of the various methods employed to study the genetics of hypertension and discuss the progress and prospects of this area of research that may contribute towards individualized clinical management of hypertension in the future.
Author: Norman M. Kaplan
Publisher: Lippincott Williams & Wilkins
ISBN: 1605475033
Category : Medical
Languages : en
Pages : 480
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Book Description
Listed as the #1 reference book for hypertension by the American Society for Hypertension in 2006, this new edition presents up-to-date, practical, evidence-based recommendations for treatment and prevention of all forms of hypertension.
