Molecular Force Sensors

Molecular Force Sensors PDF Author: Rachel Bender
Publisher: American Chemical Society
ISBN: 084129917X
Category : Science
Languages : en
Pages : 201

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Book Description
Molecular force sensors are a powerful tool for studying the mechanics of cells. These sensors not only provide information on the general mechanical behavior of cells but also can help elucidate the mechanical markers of disease formation and progression. For example, can we use cell mechanics as a biomarker to diagnose cancer? What are the mechanics associated with immune system function? Can cell mechanics be used to better understand the effect of drug treatments? The number of available questions in the field of mechanobiology is endless. After reading this e-book, you will be equipped with the information needed to begin designing your own molecular force sensors, and to begin answering the multitude of questions surrounding cell mechanobiology.

Molecular Force Sensors

Molecular Force Sensors PDF Author: Rachel Bender
Publisher: American Chemical Society
ISBN: 084129917X
Category : Science
Languages : en
Pages : 201

Get Book Here

Book Description
Molecular force sensors are a powerful tool for studying the mechanics of cells. These sensors not only provide information on the general mechanical behavior of cells but also can help elucidate the mechanical markers of disease formation and progression. For example, can we use cell mechanics as a biomarker to diagnose cancer? What are the mechanics associated with immune system function? Can cell mechanics be used to better understand the effect of drug treatments? The number of available questions in the field of mechanobiology is endless. After reading this e-book, you will be equipped with the information needed to begin designing your own molecular force sensors, and to begin answering the multitude of questions surrounding cell mechanobiology.

Molecular Force Sensors

Molecular Force Sensors PDF Author: Kerstin Blank
Publisher:
ISBN:
Category :
Languages : en
Pages : 246

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Book Description


Molecular Force Sensors

Molecular Force Sensors PDF Author: Monique J. Jacobs
Publisher:
ISBN: 9789462599666
Category :
Languages : en
Pages :

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Book Description


DNA-based Molecular Force Sensors in Cytoskeletal Networks and Cells

DNA-based Molecular Force Sensors in Cytoskeletal Networks and Cells PDF Author: Meenakshi Prabhune
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

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Book Description
Eukaryotic cells are highly active and undergo force generating processes such as cell adhesion, migration and division. The cytoskeleton, a polymer meshwork in cells, plays an important role in these cellular processes. Advances in the field of biomechanics have now made it possible to measure the cellular forces in the pN range. We have designed a DNA force sensor, based on FRET, as a tool to investigate multiple cellular processes. The following work encompasses design of the DNA force sensor and validation of its working through control experiments. The sensor was tested in vitro in cyt ...

Coiled Coils as Molecular Force Sensors for the Extracellular Matrix

Coiled Coils as Molecular Force Sensors for the Extracellular Matrix PDF Author: Melis Goktas
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
Force plays a fundamental role in the regulation of biological processes. Cells can sense the mechanical properties of the extracellular matrix (ECM) by applying forces and transmitting mechanical signals. They further use mechanical information for regulating a wide range of cellular functions, including adhesion, migration, proliferation, as well as differentiation and apoptosis. Even though it is well understood that mechanical signals play a crucial role in directing cell fate, surprisingly little is known about the range of forces that define cell-ECM interactions at the molecular level. ...

Molecular Sensors and Nanodevices

Molecular Sensors and Nanodevices PDF Author: John X. J. Zhang
Publisher: Academic Press
ISBN: 0128148632
Category : Technology & Engineering
Languages : en
Pages : 600

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Book Description
Molecular Sensors and Nanodevices: Principles, Designs and Applications in Biomedical Engineering, Second Edition is designed to be used as a foundational text, aimed at graduates, advanced undergraduates, early-career engineers and clinicians. The book presents the essential principles of molecular sensors, including theories, fabrication techniques and reviews. In addition, important devices and recently, highly-cited research outcomes are also cited. This differentiates the book from other titles on the market whose primary focus is more research-oriented and aimed at more of a niche market. Covers the fundamental principles of device engineering and molecular sensing, sensor theories and applications in biomedical science and engineering Introduces nano/micro fabrication techniques, including MEMS, bioMEMS, microTAS and nanomaterials science that are essential in the miniaturization of versatile molecular sensors Explores applications of nanomaterials and biomaterials, including proteins, DNAs, nanoparticles, quantum dots, nanotubes/wires and graphene in biomedicine

Stromal Signaling in Cancer

Stromal Signaling in Cancer PDF Author:
Publisher: Academic Press
ISBN: 0323854249
Category : Medical
Languages : en
Pages : 268

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Book Description
Stromal Signaling in Cancer, Volume 154 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics surrounding cancer research. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Cancer Research series Updated release includes the latest information on Stromal Signaling in Cancer

The Cytoskeleton in T Cell Migration and Activation

The Cytoskeleton in T Cell Migration and Activation PDF Author: Jerome Delon
Publisher: Frontiers Media SA
ISBN: 2832506259
Category : Medical
Languages : en
Pages : 140

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Book Description


Feeling the Force

Feeling the Force PDF Author: Hari Shroff
Publisher:
ISBN:
Category :
Languages : en
Pages : 304

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Book Description


Noncontact Atomic Force Microscopy

Noncontact Atomic Force Microscopy PDF Author: Seizo Morita
Publisher: Springer
ISBN: 3319155881
Category : Science
Languages : en
Pages : 539

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Book Description
This book presents the latest developments in noncontact atomic force microscopy. It deals with the following outstanding functions and applications that have been obtained with atomic resolution after the publication of volume 2: (1) Pauli repulsive force imaging of molecular structure, (2) Applications of force spectroscopy and force mapping with atomic resolution, (3) Applications of tuning forks, (4) Applications of atomic/molecular manipulation, (5) Applications of magnetic exchange force microscopy, (6) Applications of atomic and molecular imaging in liquids, (7) Applications of combined AFM/STM with atomic resolution, and (8) New technologies in dynamic force microscopy. These results and technologies are now expanding the capacity of the NC-AFM with imaging functions on an atomic scale toward making them characterization and manipulation tools of individual atoms/molecules and nanostructures, with outstanding capability at the level of molecular, atomic, and subatomic resolution. Since the publication of vol. 2 of the book Noncontact Atomic Force Microscopy in 2009 the noncontact atomic force microscope, which can image even insulators with atomic resolution, has achieved remarkable progress. The NC-AFM is now becoming crucial for nanoscience and nanotechnology.