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Author: Jean Brachet
Publisher: Elsevier
ISBN: 032314716X
Category : Science
Languages : en
Pages : 527
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Book Description
Molecular Cytology, Volume 2: Cell Interactions deals with the morphology and biochemistry of the cell, with emphasis on the more dynamic aspects of cytology. It looks at gene transfer in somatic cells, nucleocytoplasmic interactions in oocytes and eggs, and cell differentiation, transformation, malignancy, aging, and death. Organized into four chapters, this volume begins with a discussion of nucleocytoplasmic interactions in somatic cells and unicellular organisms. The next chapter examines the experimental interventions at early stages in the egg cytoplasm with reference to Xenopus oocytes, as well as oogenesis, the structure and composition of the cytoplasm and the nucleus, fertilization of sea urchin eggs, and the nuclear determinants of early embryogenic development. Additionally, a chapter explains the mechanisms underlying cell senescence, arrest of cell growth, and cell death; the mechanisms of cell differentiation as the normal outcome of embryonic development; the morphological and biochemical changes that occur in cells when they become senescent; and the metastasis of cancer cells. The book concludes with a chapter that presents a few general ideas about biochemical cytology. This book is a valuable reference for cell biologists, biochemists, cytologists, advanced students, research workers, and laypersons interested in learning the fundamentals of descriptive cytology, biochemistry, embryology, genetics, and molecular biology.
Author: Jean Brachet
Publisher: Elsevier
ISBN: 032314716X
Category : Science
Languages : en
Pages : 527
Get Book Here
Book Description
Molecular Cytology, Volume 2: Cell Interactions deals with the morphology and biochemistry of the cell, with emphasis on the more dynamic aspects of cytology. It looks at gene transfer in somatic cells, nucleocytoplasmic interactions in oocytes and eggs, and cell differentiation, transformation, malignancy, aging, and death. Organized into four chapters, this volume begins with a discussion of nucleocytoplasmic interactions in somatic cells and unicellular organisms. The next chapter examines the experimental interventions at early stages in the egg cytoplasm with reference to Xenopus oocytes, as well as oogenesis, the structure and composition of the cytoplasm and the nucleus, fertilization of sea urchin eggs, and the nuclear determinants of early embryogenic development. Additionally, a chapter explains the mechanisms underlying cell senescence, arrest of cell growth, and cell death; the mechanisms of cell differentiation as the normal outcome of embryonic development; the morphological and biochemical changes that occur in cells when they become senescent; and the metastasis of cancer cells. The book concludes with a chapter that presents a few general ideas about biochemical cytology. This book is a valuable reference for cell biologists, biochemists, cytologists, advanced students, research workers, and laypersons interested in learning the fundamentals of descriptive cytology, biochemistry, embryology, genetics, and molecular biology.
Author: Fernando C. Schmitt
Publisher: Springer
ISBN: 3319749420
Category : Medical
Languages : en
Pages : 268
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Book Description
This book is intended for practicing pathologists and cytopathologists, as well as for pathology trainees and cytotechnicians. It starts with a detailed description of the extremely important pre-analytical phase for molecular testing followed by a presentation of the key tests and their application in different organs, e.g. the lung or thyroid. Step-by-step instructions for the different assays, reporting and clinical integration of the test results are discussed. The authors help the reader to benefit from their experiences by providing a valuable tool for the implementation of these techniques in daily practice. Though the use of molecular techniques is well established in surgical biopsies, to date they are not widely used in connection with cytological material. However, in some fields like lung cancer or aspirates from the pancreas and biliary tract the only available material for diagnosis is the cytological preparation a fact that has created a need for the standardization of molecular techniques on cytology.
Author: Sinchita Roy-Chowdhuri
Publisher: Springer
ISBN: 3319973975
Category : Medical
Languages : en
Pages : 534
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Book Description
Molecular diagnostics are increasingly used to help guide targeted therapy in solid organ tumors and hematologic malignancies. A large proportion of molecular testing is performed on limited-volume samples obtained via minimally invasive techniques, such as fine needle aspiration. Increasingly, cytopathologists play an essential role in this process, both in the triage of specimens during rapid on-site evaluation and in the evaluation of archival samples to determine suitability for ancillary testing. Therefore, it is imperative that practicing cytopathologists stay abreast of up-to-date diagnostic, prognostic, and predictive ancillary tests that can be used on limited cytologic material. This is a challenge since the landscape of known genomic alterations is constantly evolving and the subsequent set of testing options is ever expanding. The proposed text will provide a user-friendly quick-reference handbook to serve as a useful resource for practicing pathologists and laboratory personnel dealing with, and interested in, this evolving field of molecular cytopathology. Essential components to be presented include: 1) pre-analytic factors that affect sample selection and evaluation; 2) specimen preparation to maximize confidence in results; 3) interpretation of results; 4) potential limitations; and 5) workflow algorithms. In addition, specific disease specific molecular testing details will be outlined to provide the reader with resources for quick reference. All chapters will be written by experts in their fields and will include the most up-to-date scientific and clinical information. Molecular Diagnostics in Cytopathology will be of value to Cytopathologists, Cytotechnologists, Cytotechnology students, Cytopathology fellows, Surgical pathologists, Pathology residents and fellows, Molecular Pathologists, Molecular pathology fellows, Molecular technologists, as well as Translational researchers with an interest in molecular cytopathology.
Author: A. Lima-de-Faria
Publisher:
ISBN:
Category : Cell transformation
Languages : en
Pages : 1508
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Book Description
Author: Jean Brachet
Publisher:
ISBN: 9780121233730
Category : Cells
Languages : en
Pages : 936
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Book Description
Author: Jean Brachet
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Jean Brachet
Publisher:
ISBN:
Category : Cells
Languages : en
Pages : 536
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Book Description
Molecular Cytology, Volume 2: Cell Interactions deals with the morphology and biochemistry of the cell, with emphasis on the more dynamic aspects of cytology. It looks at gene transfer in somatic cells, nucleocytoplasmic interactions in oocytes and eggs, and cell differentiation, transformation, malignancy, aging, and death. Organized into four chapters, this volume begins with a discussion of nucleocytoplasmic interactions in somatic cells and unicellular organisms. The next chapter examines the experimental interventions at early stages in the egg cytoplasm with reference to Xenopus oocytes ...
Author: R. Paramanantham
Publisher:
ISBN:
Category :
Languages : en
Pages : 598
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Book Description
Author: Jean Brachet
Publisher:
ISBN:
Category : Cytology
Languages : en
Pages :
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Book Description
Author: Lynn Scott Glen Pierce
Publisher:
ISBN: 9781788821612
Category :
Languages : en
Pages : 288
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Book Description
