Molecular Biology of Metal Homeostasis and Detoxification PDF Download
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Author: Markus J. Tamás
Publisher: Springer Science & Business Media
ISBN: 3540317198
Category : Science
Languages : en
Pages : 519
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Book Description
One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.
Author: Markus J. Tamás
Publisher: Springer Science & Business Media
ISBN: 3540317198
Category : Science
Languages : en
Pages : 519
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Book Description
One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.
Author: Dietrich H. Nies
Publisher: Springer Science & Business Media
ISBN: 3540697713
Category : Science
Languages : en
Pages : 455
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Book Description
This book covers allocation of metals in cells, metal transporter, storage and metalloregulatory proteins, cellular responses to metal ion stress, transcription of genes involved in metal ion homeostasis, uptake of essential metals, metal efflux and other detoxification mechanisms. The book also discusses metal bioreporters for the nanomolar range of concentration and tools to address the metallome. In addition, coverage details specific metals.
Author: Jose M. Arguello
Publisher: Academic Press
ISBN: 0123943906
Category : Science
Languages : en
Pages : 478
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Book Description
This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise
Author: Rudolfs K. Zalups
Publisher: CRC Press
ISBN: 142005998X
Category : Medical
Languages : en
Pages : 442
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Book Description
With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses
Author: M. H. Fulekar
Publisher: Springer Science & Business Media
ISBN: 9048136784
Category : Technology & Engineering
Languages : en
Pages : 391
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Book Description
Environmental pollutants have become a major global concern. The modern growth of industrialization, urbanization, modern agricultural development and energy generation have resulted in indiscriminate exploitation of natural resources for fulfilling the human desires and needs, which have contributed in disturbing the ecological balance on which the quality of environment depends. The modern technological advancements in chemical processes/operations have been raised to new products and also new pollutants in abundant level which are above the self cleaning capacity of the environment. One of the major issues in present times is the threat to human lives, due to the progressive deterioration of the environment. This book discusses bioremediation technology-based remediation to restore contaminated sites and protect the environment. It studies the opportunities for more efficient biological processes in molecular biology and ecology. Notable accomplishments of these studies include the cleaning up of polluted water and contaminated land. The book includes invited papers by eminent contributors who provide cost-effective bioremediation strategies to immobilize contaminants for cleanup of environment. The book is directed towards postgraduate students in biotechnology/life sciences/environmental sciences/biosciences and researchers in universities and research institutes and industries.
Author: Parvaiz Ahmad
Publisher: Elsevier
ISBN: 0128031832
Category : Technology & Engineering
Languages : en
Pages : 654
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Book Description
Plant Metal Interaction: Emerging Remediation Techniques covers different heavy metals and their effect on soils and plants, along with the remediation techniques currently available. As cultivable land is declining day-by-day as a result of increased metals in our soil and water, there is an urgent need to remediate these effects. This multi-contributed book is divided into four sections covering the whole of plant metal interactions, including heavy metals, approaches to alleviate heavy metal stress, microbial approaches to remove heavy metals, and phytoremediation. - Provides an overview of the effect of different heavy metals on growth, biochemical reactions, and physiology of various plants - Serves as a reference guide for available techniques, challenges, and possible solutions in heavy metal remediation - Covers sustainable technologies in uptake and removal of heavy metals
Author: Robert R. Crichton
Publisher: Elsevier
ISBN: 0080556221
Category : Science
Languages : en
Pages : 383
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Book Description
The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on.Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject.Many colour illustrations. Enables easier visualization of molecular mechanismsWritten by a single author. Ensures homgeneity of style and effective cross referencing between chapters
Author: Simon Silver
Publisher: Springer Science & Business Media
ISBN: 1461559936
Category : Science
Languages : en
Pages : 479
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Book Description
This is the first volume on the role of metal ions in regulating genes to focus not only on toxicity effects of metals but also on the role of metal ions in normal metabolisms, in both prokaryotes and in eukaryotes. This book is a comprehensive treatment of the role of metal ions in gene regulation, and it will be of great utility for those doing basic biological and biomedical research.
Author: M. N. V. Prasad
Publisher: John Wiley & Sons
ISBN: 0470355093
Category : Science
Languages : en
Pages : 675
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Book Description
Access state-of-the-art research about trace element contamination and its impact on human health in Trace Elements as Contaminants and Nutrients: Consequences in Ecosystems and Human Health. In this ground-breaking guide, find exhaustive evidence of trace element contamination in the environment with topics like the functions and essentiality of trace metals, bioavailability and uptake biochemistry, membrane biochemistry and transport mechanisms, and enzymology. Find case studies that will reinforce the fundamentals of mineral nutrition in plants and animals and current information about fortified foods and nutrient deficiencies.
Author: David Stern
Publisher: Academic Press
ISBN: 0080919561
Category : Science
Languages : en
Pages : 1120
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Book Description
This second volume of The Chlamydomonas Sourcebook provides the background and techniques for using this important organism in plant research. From biogenesis of chloroplasts and mitochondria and photosynthesis to respiration and nitrogen assimilation, this volume introduces scientists to the functions of the organism. The volume then moves on to starch biosynthesis, sulfur metabolism, response to heavy metals, and hydrogen production. - Describes molecular techniques, analysis of the recently sequenced genome, and reviews of the current status of the diverse fields in which Chlamydomonas is used as a model organism - Includes contributions from leaders in particular areas of research - Provides methods for Chlamydomonas research and best practices for applications in research, including methods for culture, preservation of cultures, preparation of media, lists of inhibitors and other additives to culture media - Assists researchers with common laboratory problems such as contamination - Includes valuable student demonstrations and properties of particular strains and mutants - Edited by the leading researcher in Chlamydomonas science
